Zobrazeno 1 - 10
of 472
pro vyhledávání: '"Chun, Ng"'
Publikováno v:
Applied Sciences, Vol 14, Iss 17, p 7707 (2024)
Skin cancer diagnosis greatly benefits from advanced machine learning techniques, particularly fine-tuned deep learning models. In our research, we explored the impact of traditional machine learning and fine-tuned deep learning approaches on predict
Externí odkaz:
https://doaj.org/article/cd4c2012cebe4790ba0104293806e6ac
Autor:
Linbin Zhou, Bo Man Ho, Hoi Ying Emily Chan, Yan Tong, Lin Du, Jing Na He, Danny Siu-Chun Ng, Clement C. Tham, Chi Pui Pang, Wai Kit Chu
Publikováno v:
Journal of Innate Immunity, Vol 15, Iss 1, Pp 739-750 (2023)
Cyclic GMP-AMP (cGAMP) synthase (cGAS), a sensor of cytosolic DNA, recognizes cytoplasmic nucleic acids to activate the innate immune responses via generation of the second messenger cGAMP and subsequent activation of the stimulator of interferon gen
Externí odkaz:
https://doaj.org/article/0653330f591d4f2c9140acf869172ca7
Autor:
Kenrie P.Y. Hui, John C.W. Ho, Ka-Chun Ng, Samuel M.S. Cheng, Ko-Yung Sit, Timmy W.K. Au, Leo L.M. Poon, John M. Nicholls, Malik Peiris, Michael C.W. Chan
Publikováno v:
Emerging Infectious Diseases, Vol 29, Iss 6, Pp 1210-1214 (2023)
Human infection with avian influenza A(H3N8) virus is uncommon but can lead to acute respiratory distress syndrome. In explant cultures of the human bronchus and lung, novel H3N8 virus showed limited replication efficiency in bronchial and lung tissu
Externí odkaz:
https://doaj.org/article/28fa9c8feae14580b4d42dc632720353
Autor:
Rui Chen, Kenrie Pui-Yan Hui, Yingmin Liang, Ka-Chun Ng, John Malcolm Nicholls, Mary Sau-Man Ip, Malik Peiris, Michael Chi-Wai Chan, Judith Choi-Wo Mak
Publikováno v:
Virology Journal, Vol 20, Iss 1, Pp 1-12 (2023)
Abstract Background The coronavirus disease 2019 (COVID-19), which is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has become a worldwide pandemic with over 627 million cases and over 6.5 million deaths. It was reported tha
Externí odkaz:
https://doaj.org/article/540268335bd646368e14a605b2ddfc05
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
The permeability barrier of the nuclear pore assembles from cohesive FG repeats. By systematic engineering and testing repeat variants, the authors pinpointed the sequence features that rule barrier assembly and transport selectivity.
Externí odkaz:
https://doaj.org/article/4e4b8add0c7b49d7906b6421c1030485
Autor:
Kai On Chu, Yolanda Wong Ying Yip, Kwok Ping Chan, Chi Chiu Wang, Danny Siu Chun Ng, Chi Pui Pang
Publikováno v:
Antioxidants, Vol 13, Iss 2, p 235 (2024)
Retinal detachment (RD) can result in the loss of photoreceptors that cause vision impairment and potential blindness. This study explores the protective effects of the oral administration of green tea extract (GTE) in a rat model of RD. Various dose
Externí odkaz:
https://doaj.org/article/f0267b3e743c4e2b8fdfca360d70be32
Autor:
Wing Lam, Kenny Dang, Cheuk Him Man, Xiao-Yuan Zeng, Lichuan Zheng, Nelson Ka-Lam Ng, Koon-Chuen Chan, Tsz-Ho Kwok, Timothy Chi-Chun Ng, Wing-Yan Leung, Michael Shing-Yan Huen, Carmen Chak-Lui Wong, Chi Wai Eric So, Zhixun Dou, Mark Robert Bray, Tak Mak, Anskar Yh Leung
Publikováno v:
HemaSphere, Vol 7, p e87320b0 (2023)
Externí odkaz:
https://doaj.org/article/95133beb511645219651e7d654e2337c
Autor:
Sheung Chun Ng, Dirk Görlich
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
The nuclear pore complex (NPC) barrier is a selective phase assembled from disordered but cohesive FG domains. The authors provide a thermodynamic description of an FG phase that is ultimately simplified and yet closely recapitulates NPC transport se
Externí odkaz:
https://doaj.org/article/0583b399176e4fb099e34328a7d681d8
Autor:
Linbin Zhou, Danny Siu-Chun Ng, Jason C. Yam, Li Jia Chen, Clement C. Tham, Chi Pui Pang, Wai Kit Chu
Publikováno v:
Journal of Biomedical Science, Vol 29, Iss 1, Pp 1-16 (2022)
Abstract The retinoblastoma protein (pRb) functions as a cell cycle regulator controlling G1 to S phase transition and plays critical roles in tumour suppression. It is frequently inactivated in various tumours. The functions of pRb are tightly regul
Externí odkaz:
https://doaj.org/article/65563937304245b09d21717b99aafc59
Autor:
María García-García, Sara Sánchez-Perales, Patricia Jarabo, Enrique Calvo, Trevor Huyton, Liran Fu, Sheung Chun Ng, Laura Sotodosos-Alonso, Jesús Vázquez, Sergio Casas-Tintó, Dirk Görlich, Asier Echarri, Miguel A. Del Pozo
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-21 (2022)
The translation of mechanical cues into gene expression changes is dependent on the nuclear import of mechanoresponsive transcriptional regulators. Here the authors identify that Importin-7 drives the nuclear import of one such regulator YAP while YA
Externí odkaz:
https://doaj.org/article/7cb59e3af2ed46b8b24506a9c27680be