Zobrazeno 1 - 10
of 251
pro vyhledávání: '"Chulhee, Choi"'
Autor:
Hae-In Lee, Min-Joo Ahn, Jae-Kwang Yoo, So-Hee Ahn, Seon Young Park, Hyangmi Seo, Moon-Ju Kim, Yu Jeong Lee, Hyun Hee Jang, Seung Cheol Shim, Eun Jeong Won, Cheolhyoung Park, Chulhee Choi, Tae-Jong Kim
Publikováno v:
Arthritis Research & Therapy, Vol 26, Iss 1, Pp 1-13 (2024)
Abstract Background This study aims to investigate the potential anti-inflammatory effects of exosomes engineered to carry super-repressor IκB (Exo-srIκB), an exosome-based NF-κB inhibitor, in the context of RA. Methods Peripheral blood mononuclea
Externí odkaz:
https://doaj.org/article/6e90f45f841845ca8162079ca99c48fa
Autor:
Sang-Won Kim, Kyung-Min Lim, Ssang-Goo Cho, Bokyeong Ryu, C-Yoon Kim, Seon Young Park, Kyungmin Jang, Jae Heon Jung, Cheolhyoung Park, Chulhee Choi, Jung-Hyun Kim
Publikováno v:
Animals, Vol 14, Iss 2, p 282 (2024)
Canine atopic dermatitis (CAD) is a genetically predisposed inflammatory pruritic skin disease. The available treatments for CAD have several adverse effects and vary in efficacy, indicating the need for the development of improved treatments. In thi
Externí odkaz:
https://doaj.org/article/c85643112799442f9ecedcd1ad50c481
Publikováno v:
Kidney Research and Clinical Practice, Vol 40, Iss 2, Pp 194-207 (2021)
Extracellular vesicles (EVs), such as exosomes and microvesicles, are cell-derived lipid bilayer membrane particles, which deliver information from host cells to recipient cells. EVs are involved in various biological processes including the modulati
Externí odkaz:
https://doaj.org/article/670d176cbce2466f8098b135dd1c1bbe
Autor:
Ji Seon Chae, Hyunju Park, So-Hee Ahn, Eun-Chong Han, Yoonjin Lee, Youn Jin Kim, Eun-Jin Ahn, Hye-Won Oh, Hyun Jung Lee, Chulhee Choi, Youn-Hee Choi, Won-joong Kim
Publikováno v:
Pharmaceutics, Vol 15, Iss 2, p 553 (2023)
Complex regional pain syndrome (CRPS) is a condition associated with neuropathic pain that causes significant impairment of daily activities and functioning. Nuclear factor kappa B (NFκB) is thought to play an important role in the mechanism of CRPS
Externí odkaz:
https://doaj.org/article/b4bc6a919f1d49558a81c90839cbb0d5
Autor:
Hee-Hoon Kim, Young-Ri Shim, Sung Eun Choi, Tolulope Esther Falana, Jae-Kwang Yoo, So-Hee Ahn, Minhye Park, Hyangmi Seo, Chulhee Choi, Won-Il Jeong
Publikováno v:
Pharmaceutics, Vol 15, Iss 2, p 636 (2023)
Activation of Kupffer cells (KCs) by gut-derived lipopolysaccharide (LPS) instigates nuclear factor-κB (NF-κB)-mediated inflammatory responses in alcohol-associated liver diseases (ALD). Here, we utilized a novel optogenetically engineered exosome
Externí odkaz:
https://doaj.org/article/bfa0bbfbf3c44aae8bfe20f78b1af6fb
Mesenchymal Stem Cell‐Derived Extracellular Vesicles as Therapeutics and as a Drug Delivery Platform
Publikováno v:
Stem Cells Translational Medicine, Vol 8, Iss 9, Pp 880-886 (2019)
Summary Mesenchymal stem cells (MSCs) are one of the most easily accessible stem cells that can be obtained from various human tissues. They have raised considerable interests for their potential applications in tissue repair, anti‐cancer therapy,
Externí odkaz:
https://doaj.org/article/b34b4ce1b6b44a85b84a5acf8728bd90
Autor:
Hojun Choi, Myung-Yoon Kim, Dae-Hwan Kim, Hanoul Yun, Byung-Koo Oh, Su-Bin Kim, In-Ho Song, Hyun-Soo Park, Sang-Eun Kim, Cheolhyoung Park, Chulhee Choi
Publikováno v:
Pharmaceutics, Vol 14, Iss 6, p 1118 (2022)
For the successful clinical advancement of exosome therapeutics, the biodistribution and pharmacokinetic profile of exogenous exosomes in various animal models must be determined. Compared with fluorescence or bioluminescence imaging, radionuclide im
Externí odkaz:
https://doaj.org/article/e034c7def49447afae14c08e646f5cb5
Publikováno v:
Pharmaceutics, Vol 14, Iss 3, p 672 (2022)
Delivering therapeutics to the central nervous system (CNS) is difficult because of the blood–brain barrier (BBB). Therapeutic delivery across the tight junctions of the BBB can be achieved through various endogenous transportation mechanisms. Rece
Externí odkaz:
https://doaj.org/article/44f8e3cd5f9743b3a3cd1deb92c38ee0
Autor:
Hojun Choi, Hwayoung Yim, Cheolhyoung Park, So-Hee Ahn, Yura Ahn, Areum Lee, Heekyoung Yang, Chulhee Choi
Publikováno v:
Membranes, Vol 12, Iss 1, p 85 (2022)
Among extracellular vesicles, exosomes have gained great attention for their role as therapeutic vehicles for delivering various active pharmaceutical ingredients (APIs). Exosomes “armed” with anti-cancer therapeutics possess great potential for
Externí odkaz:
https://doaj.org/article/8426ba85978a4196994b2af7de848621
Autor:
Yieun Jung, So-Hee Ahn, Hyunju Park, Sang Hui Park, Kyungsun Choi, Chulhee Choi, Jihee Lee Kang, Youn-Hee Choi
Publikováno v:
Cellular Physiology and Biochemistry, Vol 48, Iss 3, Pp 1332-1346 (2018)
Background/Aims: Glioblastoma multiforme (GBM) is the most common primary brain tumor in adults. The defining characteristics of GBM are diffuse infiltration of tumor cells into normal brain parenchyma, rapid growth, a high degree of infiltration of
Externí odkaz:
https://doaj.org/article/994718fe87a64848a820c1c2d389a994