Zobrazeno 1 - 10
of 99
pro vyhledávání: '"Chul-woo Pyo"'
Autor:
Hayden Brochu, Ruihan Wang, Tammy Tollison, Chul-Woo Pyo, Alexander Thomas, Elizabeth Tseng, Lynn Law, Louis J. Picker, Michael Gale, Daniel E. Geraghty, Xinxia Peng
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-13 (2022)
The alternative splicing and genetic variations across the whole MHC-E locus of Rhesus Macaques (Mamu-E) are analysed, which provides a foundation for more comprehensive research of Mamu-E and informs translational research of CMV-based vaccines.
Externí odkaz:
https://doaj.org/article/ce27b75a4ef747ec83fe39c04b0d8f01
Autor:
Lue Ping Zhao, Terry P. Lybrand, Peter B. Gilbert, Thomas H. Payne, Chul-Woo Pyo, Daniel E. Geraghty, Keith R. Jerome
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract Extensive mutations in the Omicron spike protein appear to accelerate the transmission of SARS-CoV-2, and rapid infections increase the odds that additional mutants will emerge. To build an investigative framework, we have applied an unsuper
Externí odkaz:
https://doaj.org/article/6a6535001053414e9ccd574c6a479829
Autor:
Lue Ping Zhao, Pavitra Roychoudhury, Peter Gilbert, Joshua Schiffer, Terry P. Lybrand, Thomas H. Payne, April Randhawa, Sara Thiebaud, Margaret Mills, Alex Greninger, Chul-Woo Pyo, Ruihan Wang, Renyu Li, Alexander Thomas, Brandon Norris, Wyatt C. Nelson, Keith R. Jerome, Daniel E. Geraghty
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract SARS-CoV-2 is spreading worldwide with continuously evolving variants, some of which occur in the Spike protein and appear to increase viral transmissibility. However, variants that cause severe COVID-19 or lead to other breakthroughs have n
Externí odkaz:
https://doaj.org/article/5f9985b1bb4c430b8f6f43d880140be6
Autor:
Lue Ping Zhao, George K. Papadopoulos, Antonis K. Moustakas, George P. Bondinas, Annelie Carlsson, Helena Elding Larsson, Johnny Ludvigsson, Claude Marcus, Martina Persson, Ulf Samuelsson, Ruihan Wang, Chul-Woo Pyo, Daniel E. Geraghty, Åke Lernmark
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-19 (2021)
Abstract HLA-DQ molecules account over 50% genetic risk of type 1 diabetes (T1D), but little is known about associated residues. Through next generation targeted sequencing technology and deep learning of DQ residue sequences, the aim was to uncover
Externí odkaz:
https://doaj.org/article/74813d36caef4a368c740f9032ef0809
The KAG motif of HLA-DRB1 (β71, β74, β86) predicts seroconversion and development of type 1 diabetes
Autor:
Lue Ping Zhao, George K Papadopoulos, Terry P. Lybrand, Antonis K. Moustakas, George P. Bondinas, Annelie Carlsson, Helena Elding Larsson, Johnny Ludvigsson, Claude Marcus, Martina Persson, Ulf Samuelsson, Ruihan Wang, Chul-Woo Pyo, Wyatt C. Nelson, Daniel E. Geraghty, Stephen S. Rich, Åke Lernmark
Publikováno v:
EBioMedicine, Vol 69, Iss , Pp 103431- (2021)
Background: HLA-DR4, a common antigen of HLA-DRB1, has multiple subtypes that are strongly associated with risk of type 1 diabetes (T1D); however, some are risk neutral or resistant. The pathobiological mechanism of HLA-DR4 subtypes remains to be elu
Externí odkaz:
https://doaj.org/article/298f1a40bf1e4c889622fbd1193abbd1
Autor:
David Roe, Cynthia Vierra-Green, Chul-Woo Pyo, Daniel E. Geraghty, Stephen R. Spellman, Martin Maiers, Rui Kuang
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/51f8ee94cd1e4e48876e486155b76f08
Autor:
Lue Ping Zhao, Pavitra Roychoudhury, Peter Gilbert, Joshua Schiffer, Terry P. Lybrand, Thomas H. Payne, April Randhawa, Sara Thiebaud, Margaret Mills, Alex Greninger, Chul-Woo Pyo, Ruihan Wang, Renyu Li, Alexander Thomas, Brandon Norris, Wyatt C. Nelson, Keith R. Jerome, Daniel E. Geraghty
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-2 (2022)
Externí odkaz:
https://doaj.org/article/cd4aeff26d4143ea9c400dce91964f91
Autor:
David Roe, Cynthia Vierra-Green, Chul-Woo Pyo, Daniel E. Geraghty, Stephen R. Spellman, Martin Maiers, Rui Kuang
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Human chromosome 19q13.4 contains genes encoding killer-cell immunoglobulin-like receptors (KIR). Reported haplotype lengths range from 67 to 269 kb and contain 4 to 18 genes. The region has certain properties such as single nucleotide variation, str
Externí odkaz:
https://doaj.org/article/d2b884d1e9574da58568491cb4e10979
Autor:
Chul-Woo Pyo, Lisbeth A Guethlein, Quyen Vu, Ruihan Wang, Laurent Abi-Rached, Paul J Norman, Steven G E Marsh, Jeffrey S Miller, Peter Parham, Daniel E Geraghty
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e15115 (2010)
The fast evolving human KIR gene family encodes variable lymphocyte receptors specific for polymorphic HLA class I determinants. Nucleotide sequences for 24 representative human KIR haplotypes were determined. With three previously defined haplotypes
Externí odkaz:
https://doaj.org/article/3aca62c0fd2648c0b75ef2a4b672cf08
Autor:
Cherrelle Dacon, Courtney Tucker, Linghang Peng, Chang-Chun D. Lee, Ting-Hui Lin, Meng Yuan, Yu Cong, Lingshu Wang, Lauren Purser, Jazmean K. Williams, Chul-Woo Pyo, Ivan Kosik, Zhe Hu, Ming Zhao, Divya Mohan, Andrew J. R. Cooper, Mary Peterson, Jeff Skinner, Saurabh Dixit, Erin Kollins, Louis Huzella, Donna Perry, Russell Byrum, Sanae Lembirik, David Drawbaugh, Brett Eaton, Yi Zhang, Eun Sung Yang, Man Chen, Kwanyee Leung, Rona S. Weinberg, Amarendra Pegu, Daniel E. Geraghty, Edgar Davidson, Iyadh Douagi, Susan Moir, Jonathan W. Yewdell, Connie Schmaljohn, Peter D. Crompton, Michael R. Holbrook, David Nemazee, John R. Mascola, Ian A. Wilson, Joshua Tan
Publikováno v:
Science. 377:728-735
The potential for future coronavirus outbreaks highlights the need to broadly target this group of pathogens. We used an epitope-agnostic approach to identify six monoclonal antibodies that bind to spike proteins from all seven human-infecting corona
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00be51410add1f540a8cd59d08b048c3
https://doi.org/10.1126/science.abq3773
https://doi.org/10.1126/science.abq3773