Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Chul-Hoon Lee"'
Publikováno v:
Biochemical and Biophysical Research Communications. 512:314-318
Plasmin is a potent serin protease involved in a variety of biological functions, such as fibrinolysis and tissue remodeling. On performing an in vitro control assay to measure the activity of endogenous plasmin in cell lysates, a stimulatory effect
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 26:1130-1135
Prostate cancer is the most frequently diagnosed cancer and is one of the leading causes of male cancer death in the world. Recently, in the course of our screening for a novel anticancer compound, we synthesized carbocyclic analogs of pyrrolo[2,3-d]
Publikováno v:
Anticancer research. 36(1)
Previously, we synthesized a new carbocyclic analog of pyrrolo[2,3-d]pyrimidine nucleoside, designated MCS-C3. Recently, we found that LNCaP androgen-responsive prostate cancer cells treated with MCS-C3 rapidly undergo intrinsic apoptosis through dra
Publikováno v:
Biotechnology Advances. 30:202-209
Tautomycetin (TMC) is an unusual linear polyketide compound esterified with a cyclic anhydride. It exhibits novel activated T cell-specific immunosuppressant as well as anti-cancer activities. Previously, we isolated and characterized the entire TMC
Autor:
Chul-Hoon Lee, Seon-A Jang, Ki-Hyo Jang, Hye-Jin Park, Se-Chan Kang, Eun-Hwa Sohn, Suhkneung Pyo
Publikováno v:
Journal of Ginseng Research
Atopic dermatitis (AD) is an allergic, inflammatory skin disease characterized by chronic eczema and mechanical injury to the skin, caused by scratching. Korean red ginseng (RG) has diverse biological activities, but the molecular effects of RG on al
Autor:
Hyoung Jin Kim, Chul-Hoon Lee, Sun-Young Kim, Meerim Park, Ho-Joon Im, Kyung-Nam Koh, Hee Jin Kim, Jong-Jin Seo
Publikováno v:
The Korean Journal of Hematology
BACKGROUND It has been hypothesized that genetic alteration at the cellular level may have a significant effect on cellular mechanisms controlling the proliferation and apoptosis of Langerhans cells (LCs). METHODS We examined whether p16 protein expr
Publikováno v:
Journal of microbiology and biotechnology. 25(6)
We examined the in vivo efficacy of ultra-high molecular weight poly-γ-glutamic acid (UHMW γ-PGA) for wound healing. The wound area was measured by a ruler and documented by digital photography before the animals were sacrificed at days 8 and 16 po
Publikováno v:
Journal of microbiology and biotechnology. 25(3)
We investigated the effect of ultra-high molecular weight poly-γ-glutamic acid (UHMW γ-PGA) on hair loss in vitro and in vivo. 5-Alpha reductase is an enzyme that metabolizes the male hormone testosterone into dihydrotestosterone. By performing an
Publikováno v:
European Journal of Immunology. 35:2648-2657
The approximately 20-kDa heat-labile toxin produced by enterotoxigenic Bacteroides fragilis is known to be associated with the development of enteritis. However, the molecular mechanism involved is not yet fully understood. In this study, we assessed