Zobrazeno 1 - 10
of 224
pro vyhledávání: '"Chul-Ho Yun"'
Autor:
Su-Min Yee, Harim Choi, Jeong-Eun Seon, Yu-Jin Ban, Min-Jae Kim, Jae-Eun Seo, Ja Hun Seo, Sehyeon Kim, Seo Hee Moon, Chul-Ho Yun, Hyang Burm Lee, Hyung-Sik Kang
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Axl is a tyrosine kinase receptor, a negative regulator for innate immune responses and inflammatory bowel disease (IBD). The gut microbiota regulates intestinal immune homeostasis, but the role of Axl in the pathogenesis of IBD through the
Externí odkaz:
https://doaj.org/article/44204e84899644a28a526d813c1e79b0
Autor:
Su-Min Woo, Ngoc Anh Nguyen, Jeong-Eun Seon, Jin Jang, Su-Min Yee, Ngoc Tan Cao, Harim Choi, Chul-Ho Yun, Hyung-Sik Kang
Publikováno v:
Molecules, Vol 28, Iss 4, p 1851 (2023)
Phloretin and its glycoside phlorizin have been reported to prevent obesity induced by high-fat diet (HFD), but the effect of 3-OH phloretin, a catechol metabolite of phloretin, has not been investigated. In this study, we investigated the anti-obesi
Externí odkaz:
https://doaj.org/article/ea0a244a544f4c6d8121228a159bfc41
Autor:
Thien-Kim Le, Young Jin Park, Gun Su Cha, Fikri A. R. Hardiyanti Oktavia, Dong Hyun Kim, Chul-Ho Yun
Publikováno v:
Pharmaceutics, Vol 15, Iss 1, p 23 (2022)
Tenatoprazole, a newly developed proton pump inhibitor candidate, was developed as an acid inhibitor for gastric acid hypersecretion disorders such as gastric ulcer and reflux esophagitis. It is known that tenatoprazole is metabolized to three major
Externí odkaz:
https://doaj.org/article/ffe7bafbeefe4a34886c4bb06aa53f92
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 23, p 15318 (2022)
The enzymatic transformation of various chemicals, especially using NADPH-dependent hydroxylase, into more soluble and/or high value-added products has steadily garnered increasing attention. However, the industrial application of these NADPH-depende
Externí odkaz:
https://doaj.org/article/cbf9e1687bb9480ca9ef54bdbff5624f
Autor:
Hyun Min Kim, Se Hee Park, Sang Hoon Ma, Seo Young Park, Chul-Ho Yun, Geupil Jang, Young Hee Joung
Publikováno v:
Frontiers in Plant Science, Vol 11 (2020)
Abscisic acid (ABA) is a key signaling molecule that mediates plant response to stress. Increasing evidence indicates that ABA also regulates many aspects of plant development, such as seed germination, leaf development, and ripening. ABA metabolism,
Externí odkaz:
https://doaj.org/article/b23da62d36af4358b1fadadc2c28ed39
Publikováno v:
Pharmaceuticals, Vol 14, Iss 10, p 981 (2021)
Statins inhibit the 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase (HMG-CoA reductase), which is the rate-limiting enzyme in cholesterol biosynthesis. Statin therapy reduces morbidity and mortality in those who are at high risk of cardiovascular di
Externí odkaz:
https://doaj.org/article/96fd6e864b9b493f93631bb544a85449
Autor:
Ngoc Anh Nguyen, Ngoc Tan Cao, Thi Huong Ha Nguyen, Jung-Hwan Ji, Gun Su Cha, Hyung-Sik Kang, Chul-Ho Yun
Publikováno v:
Antioxidants, Vol 10, Iss 8, p 1327 (2021)
Phlorizin is the most abundant glucoside of phloretin from the apple tree and its products. Phlorizin and its aglycone phloretin are currently considered health-beneficial polyphenols from apples useful in treating hyperglycemia and obesity. Recently
Externí odkaz:
https://doaj.org/article/92a446137b9448fbbd0a93e20c92c422
Publikováno v:
Nanomaterials, Vol 11, Iss 7, p 1725 (2021)
Bottom-up micropatterning or nanopatterning can be viewed as the localization of target molecules to the desired area of a surface. A majority of these processes rely on the physical adsorption of ink-like molecules to the paper-like surface, resulti
Externí odkaz:
https://doaj.org/article/49759efa0b0c494787dc9d89a4d1f469
Publikováno v:
Catalysts, Vol 11, Iss 2, p 267 (2021)
Oleanolic acid (OA) is a pentacyclic triterpenoid widely found in plants and foods as an aglycone of triterpenoid saponins or as a free acid. OA exhibits beneficial activities for humans, including antitumor, antivirus, and hepatoprotection propertie
Externí odkaz:
https://doaj.org/article/95b442ea98714e4c8cecca0a56f76e17
Publikováno v:
Applied Sciences, Vol 11, Iss 2, p 603 (2021)
Atorvastatin is a widely used statin drug that prevents cardiovascular disease and treats hyperlipidemia. The major metabolites in humans are 2-OH and 4-OH atorvastatin, which are active metabolites known to show highly inhibiting effects on 3-hydrox
Externí odkaz:
https://doaj.org/article/45ba4ac5cd2240d09c497330d34cfed6