Zobrazeno 1 - 10
of 143
pro vyhledávání: '"Chul Ho Jeong"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Persistent neurochemical and biological disturbances resulting from repeated cycles of drug reward, withdrawal, and relapse contribute to drug dependence. Methamphetamine (MA) is a psychostimulant with substantial abuse potential and neuroto
Externí odkaz:
https://doaj.org/article/5820fdd670f245e6a1fdeb1332838782
Publikováno v:
Frontiers in Psychiatry, Vol 14 (2024)
IntroductionMethamphetamine use disorder (MUD) is a chronic relapsing disorder characterized by compulsive Methamphetamine (MA) use despite its detrimental effects on physical, psychological, and social well-being. The development of MUD is a complex
Externí odkaz:
https://doaj.org/article/501fc284e81c4d74b3ee5377afd8dd40
Autor:
Sang-Hoon Song, Won-Jun Jang, Eun Young Jang, Oc-Hee Kim, Haesoo Kim, Taekwon Son, Dong-Young Choi, Sooyeun Lee, Chul-Ho Jeong
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
MicroRNA (miRNA)-mediated striatal gene regulation may play an important role in methamphetamine (METH) addiction. This study aimed to identify changes in novel miRNAs and their target genes during METH self-administration and investigate their roles
Externí odkaz:
https://doaj.org/article/5faed25a30e445d4b2714d7a4d4544c5
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 10, p 8672 (2023)
The current method for diagnosing methamphetamine use disorder (MUD) relies on self-reports and interviews with psychiatrists, which lack scientific rigor. This highlights the need for novel biomarkers to accurately diagnose MUD. In this study, we id
Externí odkaz:
https://doaj.org/article/170f9f39fdd94fffb0a7f36b7730f1ce
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Statins, a class of lipid-lowering drugs, are used in drug repositioning for treatment of human cancer. However, the molecular mechanisms underlying statin-induced cancer cell death and autophagy are not clearly defined. In the present study, we show
Externí odkaz:
https://doaj.org/article/941ca74b9acd4b12a50620e281bf8870
Publikováno v:
Experimental and Molecular Medicine, Vol 50, Iss 7, Pp 1-13 (2018)
Protein modification: Effect on activity Enzymes that modify proteins by adding an acetyl group have profound effects on metabolism and development, as well as disease. This process, known as acetylation, is carried out by KAT proteins, which are pre
Externí odkaz:
https://doaj.org/article/b02f128f87d345e89b285e4d1736c06d
Publikováno v:
Journal of Neuroinflammation, Vol 14, Iss 1, Pp 1-15 (2017)
Abstract Background Methamphetamine (METH) is a commonly abused drug that may result in neurotoxic effects. Recent studies have suggested that involvement of neuroinflammatory processes in brain dysfunction is induced by misuse of this drug. However,
Externí odkaz:
https://doaj.org/article/f217bf2be1414fff97c04ddfa291a29a
Publikováno v:
Korean Journal of Physiology & Pharmacology; Jan2024, Vol. 28 Issue 1, p83-91, 9p
Autor:
Zigang Dong, Ki Won Lee, Ann M. Bode, Hyong Joo Lee, Mee-Hyun Lee, Ji Young Kim, Kanamata Reddy, Semi Lim, Lee Farrand, Chul-Ho Jeong, Jihoon Lee, Sung-Young Lee, Sanguine Byun
Supplementary Figures and Legends - PDF file 2854K, Supplementary Figure 1. Effect of USP8 knockdown on cell viability Supplementary Figure 2. Effect of USP8 knockdown on EGFR wildtype cells and apoptosis of NSCLC and normal cells. Supplementary Figu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15e7fdeda2a3af750cd83e459245e985
https://doi.org/10.1158/1078-0432.22446666.v1
https://doi.org/10.1158/1078-0432.22446666.v1
Autor:
Zigang Dong, Ki Won Lee, Ann M. Bode, Hyong Joo Lee, Mee-Hyun Lee, Ji Young Kim, Kanamata Reddy, Semi Lim, Lee Farrand, Chul-Ho Jeong, Jihoon Lee, Sung-Young Lee, Sanguine Byun
Purpose: Common treatment modalities for non–small cell lung cancer (NSCLC) involve the EGF receptor-tyrosine kinase inhibitors (EGFR-TKIs) like gefitinib and erlotinib. However, the vast majority of treated patients acquire resistance to EGFR-TKIs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1ab5b1cf4a0a64f346025f31013716d
https://doi.org/10.1158/1078-0432.c.6520821.v1
https://doi.org/10.1158/1078-0432.c.6520821.v1