Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Chujie, Chen"'
Publikováno v:
Journal of Orthopaedic Surgery, Vol 32 (2024)
Background Knee osteoarthritis (KOA) is a multifactorial whole-joint disease with a high rate of disability. Considering the complexity of KOA, there is an urgent need to discover new molecular pathological markers and multi-target treatment strategi
Externí odkaz:
https://doaj.org/article/f00c88d90da94a95add5654f814d0dac
Autor:
Mingwei Yang, Miyang Yang, Lanlan Yang, Zhaochu Wang, Peiyun Ye, Chujie Chen, Liyuan Fu, Shangwen Xu
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
Rectal cancer (RC) is a globally prevalent malignant tumor, presenting significant challenges in its management and treatment. Currently, magnetic resonance imaging (MRI) offers superior soft tissue contrast and radiation-free effects for RC patients
Externí odkaz:
https://doaj.org/article/eca60f15b9844340aac4012846238732
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
The prevalence of pelvic organ prolapse (POP) has been steadily increasing over the years, rendering it a pressing global health concern that significantly impacts women’s physical and mental wellbeing as well as their overall quality of life. With
Externí odkaz:
https://doaj.org/article/b16cdd20c63d4f36842ee87dae51b563
Autor:
Dong Xu, Saina Yan, Huimin Jin, Chujie Chen, Xiangwei Tang, Xu Wang, Yonghong Li, Fang Fei, Anqi Yang
Publikováno v:
Frontiers in Genetics, Vol 14 (2024)
DNMT3A participates in de novo methylation, yet its impact on the proliferation of testicular Sertoli cells remains unclear. Development-specific methylation has been proven to be associated with cellular development. Therefore, in this study, we sim
Externí odkaz:
https://doaj.org/article/52186770de0b45659dde416491e32c7a
Publikováno v:
Biomolecules, Vol 14, Iss 6, p 607 (2024)
Normal testicular development ensures the process of spermatogenesis, which is a complex biological process. The sustained high productivity of spermatogenesis throughout life is predominantly attributable to the constant proliferation and differenti
Externí odkaz:
https://doaj.org/article/b24da59924cf44a1baa8b4e364f37c1b
Publikováno v:
Current Urology, Vol 17, Iss 1, Pp 45-51 (2023)
Abstract. Increasing evidence indicates that N6-methyladenosine (m6A) methylation modification serves important functions in biological metabolism. Dysregulation of m6A regulators is related to the progression of different malignancies, including ren
Externí odkaz:
https://doaj.org/article/5147dffd02ab42d8a80106f9bd1300b3
Autor:
Chujie Chen, Xiangwei Tang, Saina Yan, Anqi Yang, Jiaojiao Xiang, Yanhong Deng, Yulong Yin, Bin Chen, Jingjing Gu
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 19, p 14475 (2023)
RNA N6-methyladenosine (m6A) modification is one of the principal post-transcriptional modifications and plays a dynamic role in testicular development and spermatogenesis. However, the role of m6A in porcine testis is understudied. Here, we performe
Externí odkaz:
https://doaj.org/article/969f362ec8774c3793f2d9a2a9da0673
Autor:
Jun Li, Shiqiang Zhang, Dingzhun Liao, Qian Zhang, Chujie Chen, Xiangwei Yang, Donggen Jiang, Jun Pang
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-11 (2022)
Abstract Background Cancer cells prefer utilizing aerobic glycolysis in order to exacerbate tumor mass and maintain un-regulated proliferative rates. As a key glycolytic activator, phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3) has bee
Externí odkaz:
https://doaj.org/article/f00e0d1667cb451d9e1151c08ee9096b
Publikováno v:
Genes, Vol 14, Iss 6, p 1211 (2023)
In the genomes of diploid organisms, runs of homozygosity (ROH), consecutive segments of homozygosity, are extended. ROH can be applied to evaluate the inbreeding situation of individuals without pedigree data and to detect selective signatures via R
Externí odkaz:
https://doaj.org/article/87a4e67250504238931385f24c4cd39b
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 7, p 6179 (2023)
The regulatory role of non-CpG methylation in mammals has been important in whole-genome bisulfite sequencing. It has also been suggested that non-CpG methylation regulates gene expression to affect the development and health of mammals. However, the
Externí odkaz:
https://doaj.org/article/a67d4235c88643eea055a556e41c8403