Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Chufan Cai"'
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/99e1ec63ea5546d1b86cfb20a63da372
Autor:
Alan Y. Hsu, Theodore Gurol, Tiago J. P. Sobreira, Sheng Zhang, Natalie Moore, Chufan Cai, Zhong-Yin Zhang, Qing Deng
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Endotoxemia is a condition in which endotoxins enter the blood stream and cause systemic and sometimes lethal inflammation. Zebra fish provides a genetically tractable model organism for studying innate immunity, with additional advantages in live im
Externí odkaz:
https://doaj.org/article/b5bb62efcc404b5fbd73cc55f9dc442e
Autor:
Michele Ciboddo, Jonathan Dowgielewicz, George Yan, Deborah Rodriguez, Hunter Blaylock, Nicole Arellano, Chad Coen, Chufan Cai, Nia Hammond, Alex Rosencrance, Elisa Rumi, Daniela Pietra, Daniele Vanni, Silvia Catricalà, Ilaria Carola Casetti, Oscar Borsani, Brandon Faubert, Shannon Elf
Publikováno v:
Cancer Research. 83:LB256-LB256
Myeloproliferative neoplasms (MPNs) comprise a group of cancers of the bone marrow that can transform into a post-MPN acute myeloid leukemia (AML), at which point the overall survival rate is less than 6 months. JAK2 inhibitors in MPN failed to alter
Autor:
Chufan Cai, Jiayi Tu, Jeronimo Najarro, Rukang Zhang, Xue Gao, Hao Fan, Freya Zhang, Jiacheng Li, Michele Ciboddo, Shannon Elf, Rong Wu, Jing Chen
Publikováno v:
Cancer Research. 83:283-283
Cancer cells apply metabolic adaptations for proliferation and survival such as the Warburg Effect and the maintenance of redox balance, which are common for different cancer types. However, it remains elusive whether different cancer oncogenic backg
Publikováno v:
Applied Biochemistry and Microbiology. 57:481-492
Extracellular protease SptA from the halophilic archaeon Natrinema sp. J7 was successfully expressed in Bacillus subtilis SCK6 using touchdown two-step PCR and plasmid multimer. Culture optimization was conducted to increase SptA protease activity 13
Autor:
Chufan Cai
Publikováno v:
Cancer Research. 82:6197-6197
Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers, with a five-year survival rate ~10%1. PDAC is characterized by an altered/abnormal nutrient tumormicroenvironment (TME)2, and cancer cells must adapt metabolically, which expose
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
BackgroundWhile CD8 T cells are crucial for anti-tumor immunity, tumor infiltrating CD8 T cells encounter stressors which deviate their differentiation to a dysfunctional, exhausted phenotype. T cell functions are closely regulated by T cell metaboli
Autor:
Jian Qin, Wei Feng, Hans Schreiber, Yanran He, Chufan Cai, Huada Lian, Enfu Hui, Sobhan Roy, Dibyendu Kumar Sasmal, Jun Huang, Erin J. Adams, Peter Leung, Guoshuai Cao
Publikováno v:
Cellular and Molecular Immunology
A major unanswered question is how a TCR discriminates between foreign and self-peptides presented on the APC surface. Here, we used in situ fluorescence resonance energy transfer (FRET) to measure the distances of single TCR–pMHC bonds and the con
Leather making technology is undergoing a profound change from chemical process to enzyme-assisted dehairing. In this work, the SptA protease from halophilic archaeon Natrinema sp. J7 was expressed by Bacillus subtilis SCK6. The crude enzyme extract
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c182f0487708f657f7761e4f0f930a7
Publikováno v:
Archives of microbiology. 202(6)
A novel Gram-stain-positive, motile, moderate halophile, strain L9T, was isolated from hides of white goat in China. The isolate grew optimally at 30 °C, at pH 7 and with 5–10% (w/v) NaCl. The predominant menaquinone was MK-7, and the major cellul