Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Chuen Miin Leu"'
Autor:
Murali K. Mamidi, Jifeng Huang, Kazuhito Honjo, Ran Li, Edlue M. Tabengwa, Indira Neeli, Nar’asha L. Randall, Manasa V. Ponnuchetty, Marko Radic, Chuen-Miin Leu, Randall S. Davis
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Immunotherapeutic targeting of surface regulatory proteins and pharmacologic inhibition of critical signaling pathways has dramatically shifted our approach to the care of individuals with B cell malignancies. This evolution in therapy reflects the c
Externí odkaz:
https://doaj.org/article/4bd75577d0ab4e1383a1ce91c0a9a747
Autor:
Po-Chun Liu, Chih-Tai Ssu, Yen-Po Tsao, Teh-Ling Liou, Chang-Youh Tsai, Chung-Tei Chou, Ming-Han Chen, Chuen-Miin Leu
Publikováno v:
Arthritis Research & Therapy, Vol 22, Iss 1, Pp 1-14 (2020)
Abstract Background Cytotoxic T lymphocyte-associated antigen-4-Ig (CTLA-4-Ig) competes with CD28 for binding CD80/CD86 on antigen-presenting cells (APCs) to limit T cell activation. B cells are believed to be important APCs in the pathogenesis of au
Externí odkaz:
https://doaj.org/article/54411dbe04fb4ab1b44cd1a954ff2836
Autor:
Chin-Wen Wei, Chia-Ying Lee, Ding-Jin Lee, Chang-Feng Chu, Ju-Chu Wang, Tien-Chiao Wang, Wann-Neng Jane, Zee-Fen Chang, Chuen-Miin Leu, Ivan L. Dzhagalov, Chia-Lin Hsu
Publikováno v:
Cell Reports, Vol 23, Iss 8, Pp 2330-2341 (2018)
Summary: T cells are a versatile immune cell population responding to challenges by differentiation and proliferation followed by contraction and memory formation. Dynamic metabolic reprogramming is essential for T cells to meet the biosynthetic need
Externí odkaz:
https://doaj.org/article/ffb5837ad0804470ae2240b8d75de6cf
Autor:
KUO-SHYANG JENG, PO-YU CHENG, YUEH-HSIEN LIN, PO-CHUN LIU, PING-HUI TSENG, YU-CHAO WANG, CHIUNG-FANG CHANG, CHUEN-MIIN LEU
Publikováno v:
Oncology Research; 2024, Vol. 32 Issue 1, p163-174, 12p
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 6, p 3208 (2021)
Endoglin (CD105) is a type-1 integral transmembrane glycoprotein and coreceptor for transforming growth factor-β (TGF-β) ligands. The endoglin/TGF-β signaling pathway regulates hemostasis, cell proliferation/migration, extracellular matrix (ECM) s
Externí odkaz:
https://doaj.org/article/0abe261f2bd24520878626fb0d385607
Autor:
Mamidi, Murali K., Jifeng Huang, Kazuhito Honjo, Ran Li, Tabengwa, Edlue M., Neeli, Indira, Randall, Nar'asha L., Ponnuchetty, Manasa V., Radic, Marko, Chuen-Miin Leu, Davis, Randall S.
Publikováno v:
Frontiers in Immunology; 2023, p1-16, 16p
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 18, p 6863 (2020)
Smoothened (SMO) belongs to the Hedgehog (HH) signaling pathway, which regulates cell growth, migration, invasion and stem cells in cancer. The HH signaling pathway includes both canonical and noncanonical pathways. The canonical HH pathway functions
Externí odkaz:
https://doaj.org/article/940b927de1cc4f60bca4eeb00df07eec
Autor:
Chiung‑Fang Chang, Yeou Guang Tsay, I‑Shyan Sheen, Kuo Shyang Jeng, Chuen Miin Leu, Shih‑Yun Li, Wen-Juei Jeng, Chi-Juei Jeng
Publikováno v:
Oncology Letters
Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-associated mortality worldwide. Hepatocarcinogenesis involves numerous interlinked factors and processes, including the Sonic hedgehog (Shh) signaling pathway, which participates i
Autor:
Mark Shui-Yu Liu, Shinn-Shing Lee, Eileen Jea Chien, Jiann-Jong Chen, Chau-Heng Chien, Ming-Lin Huang, Chuen-Miin Leu
Publikováno v:
Adaptive Medicine. 10:155-160
Gout is characterized by the presence of monosodium urate (MSU) crystals in joints and surrounding tissues. When MSU is detected by tissue, it is treated as "danger/ damage", and there is rapid recruitment of neutrophils from the circulation into
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 6863, p 6863 (2020)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Smoothened (SMO) belongs to the Hedgehog (HH) signaling pathway, which regulates cell growth, migration, invasion and stem cells in cancer. The HH signaling pathway includes both canonical and noncanonical pathways. The canonical HH pathway functions