Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Chuck Merryman"'
Autor:
Marian Breuer, Tyler M Earnest, Chuck Merryman, Kim S Wise, Lijie Sun, Michaela R Lynott, Clyde A Hutchison, Hamilton O Smith, John D Lapek, David J Gonzalez, Valérie de Crécy-Lagard, Drago Haas, Andrew D Hanson, Piyush Labhsetwar, John I Glass, Zaida Luthey-Schulten
Publikováno v:
eLife, Vol 8 (2019)
JCVI-syn3A, a robust minimal cell with a 543 kbp genome and 493 genes, provides a versatile platform to study the basics of life. Using the vast amount of experimental information available on its precursor, Mycoplasma mycoides capri, we assembled a
Externí odkaz:
https://doaj.org/article/8a4a0da0c3184384beb1ab8154468210
Autor:
Lin Ding, Harrison D. Macdonald, Hamilton O Smith, Clyde A. Hutchison III, Chuck Merryman, Todd P. Michael, Bradley W. Abramson, Krishna Kannan, Joe Liang, John Gill, Daniel G. Gibson, John I. Glass
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 19, p 7112 (2020)
Kluyveromyces marxianus (K. marxianus) is an increasingly popular industrially relevant yeast. It is known to possess a highly efficient non-homologous end joining (NHEJ) pathway that promotes random integration of non-homologous DNA fragments into i
Externí odkaz:
https://doaj.org/article/ef0f81f287e645d69f8477effdeb094f
Publikováno v:
Open Biology, Vol 2, Iss 10 (2012)
The sequenced genome of Mycoplasma mycoides subsp. capri revealed the presence of a Type III restriction–modification system (MmyCI). The methyltransferase (modification) subunit of MmyCI (M.MmyCI) was shown to recognize the sequence 5′-TGAG-3′
Externí odkaz:
https://doaj.org/article/d4e8a15ae4c0454cb4ec38408e9d86d4
Autor:
Clyde A. Hutchison, Andrew D. Hanson, Hamilton O. Smith, David Gonzalez, Marian Breuer, John D. Lapek, Tyler M. Earnest, Drago Haas, Chuck Merryman, Piyush Labhsetwar, Valérie de Crécy-Lagard, Lijie Sun, Kim S. Wise, John I. Glass, Michaela R Lynott, Zaida Luthey-Schulten
Publikováno v:
Elife, 8:36842. eLife Sciences Publications, Ltd
eLife
eLife, Vol 8 (2019)
eLife
eLife, Vol 8 (2019)
JCVI-syn3A, a robust minimal cell with a 543 kbp genome and 493 genes, provides a versatile platform to study the basics of life. Using the vast amount of experimental information available on its precursor, Mycoplasma mycoides capri, we assembled a
Autor:
Tyler M. Earnest, Lijie Sun, John D. Lapek, John I. Glass, Hamilton O. Smith, Chuck Merryman, Marian Breuer, Piyush Labhsetwar, Zaida Luthey-Schulten, Andrew D. Hanson, David Gonzalez, Valérie de Crécy-Lagard, Drago Haas, Clyde A. Hutchison, Michaela R Lynott, Kim S. Wise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bee24c5acf35c50724d099f6f7800ce
https://doi.org/10.7554/elife.36842.sa2
https://doi.org/10.7554/elife.36842.sa2
Autor:
Adam J. Moore, Yo Suzuki, Jaume Piñol, J. Craig Venter, Lijie Sun, Kazuki Tanaka, Alicia Broto, Carlos Piñero-Lambea, Gavin Tse, Clyde A. Hutchison, Enrique Querol, Luis González-González, Maria Lluch-Senar, Chuck Merryman, John I. Glass, Hamilton O. Smith, Shigeyuki Kakizawa, Masaru Tomita, Kim S. Wise, Ana M. Mariscal, Philip D. Weyman, Jonathan Y. Hsu
Publikováno v:
Recercat. Dipósit de la Recerca de Catalunya
instname
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
ACS Synthetic Biology
Recercat: Dipósit de la Recerca de Catalunya
Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
instname
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
ACS Synthetic Biology
Recercat: Dipósit de la Recerca de Catalunya
Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Functional genomics studies in minimal mycoplasma cells enable unobstructed access to some of the most fundamental processes in biology. Conventional transposon bombardment and gene knockout approaches often fail to reveal functions of genes that are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::968d4b854f5a31da7542f3c785472b96
https://ddd.uab.cat/record/225194
https://ddd.uab.cat/record/225194
Autor:
Jiqiang Ling, Jesse Rinehart, John I. Glass, Laure Prat, Radha Krishnakumar, Hans R. Aerni, Dieter Söll, Chuck Merryman
Publikováno v:
ChemBioChem. 14:1967-1972
Sense codon recoding is the basis for genetic code expansion with more than two different noncanonical amino acids. It requires an unused (or rarely used) codon, and an orthogonal tRNA synthetase:tRNA pair with the complementary anticodon. The Mycopl
Autor:
Nacyra Assad-Garcia, Ray-Yuan Chuang, Hamilton O. Smith, Clyde A. Hutchison, Li Ma, Billyana Tsvetanova, Daniel G. Gibson, J. Craig Venter, Chuck Merryman, Krishna Kannan, John I. Glass, Vladimir N. Noskov
Publikováno v:
Scientific Reports
Bacteria are indispensable for the study of fundamental molecular biology processes due to their relatively simple gene and genome architecture. The ability to engineer bacterial chromosomes is quintessential for understanding gene functions. Here we
Autor:
James F. Pelletier, Vladimir N. Noskov, Krishna Kannan, Billyana Tsvetanova, John I. Glass, Hamilton O. Smith, Bogumil J. Karas, Kim S. Wise, John Gill, J. Craig Venter, Yo Suzuki, Chuck Merryman, Daniel G. Gibson, Clyde A. Hutchison, Lijie Sun, R. Alexander Richter, Zhi Qing Qi, Nacyra Assad-Garcia, Ray-Yuan Chuang, Mark H. Ellisman, Elizabeth A. Strychalski, Thomas J. Deerinck, Li Ma
Publikováno v:
Science. 351
Designing and building a minimal genome A goal in biology is to understand the molecular and biological function of every gene in a cell. One way to approach this is to build a minimal genome that includes only the genes essential for life. In 2010,
Autor:
Chuck Merryman, Daniel G. Gibson
Publikováno v:
Metabolic Engineering. 14:196-204
The construction of large DNA molecules that encode pathways, biological machinery, and entire genomes has been limited to the reproduction of natural sequences. However, now that robust methods for assembling hundreds of DNA fragments into construct