Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Chuck Haggerty"'
Autor:
Raha Weigert, Sara Hetzel, Nina Bailly, Chuck Haggerty, Ibrahim A. Ilik, Philip Yuk Kwong Yung, Carmen Navarro, Adriano Bolondi, Abhishek Sampath Kumar, Chiara Anania, Björn Brändl, David Meierhofer, Darío G. Lupiáñez, Franz-Josef Müller, Tugce Aktas, Simon J. Elsässer, Helene Kretzmer, Zachary D. Smith, Alexander Meissner
Publikováno v:
Nature Cell Biology
DNA and Histone 3 Lysine 27 methylation typically function as repressive modifications and operate within distinct genomic compartments. In mammals, the majority of the genome is kept in a DNA methylated state, whereas the Polycomb repressive complex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d193c70d47a07e4ccd7fa7838357e2d0
https://hdl.handle.net/21.11116/0000-000D-1F8D-321.11116/0000-000D-1F8F-1
https://hdl.handle.net/21.11116/0000-000D-1F8D-321.11116/0000-000D-1F8F-1
Autor:
David Meierhofer, Raha Weigert, Nina Bailly, Claudia Giesecke-Thiel, Judith Gottfreund, Chuck Haggerty, Alexander Meissner, Jörn Walter, Christina Galonska, Abhishek Sampath Kumar, Thorsten Mielke, Franz-Josef Müller, Björn Brändl, Pascal Giehr, Helene Kretzmer, Bernd Timmermann, Lars Wittler, Ferdinand von Meyenn, René Buschow, Christina Riemenschneider, Alexandra L. Mattei, Melissa B. Pappalardi, Pay Giesselmann, Michael T. McCabe
Publikováno v:
Nature Structural and Molecular Biology
Nature Structural & Molecular Biology
Nature Structural & Molecular Biology, 28 (7)
Nature Structural & Molecular Biology
Nature Structural & Molecular Biology, 28 (7)
DNA methylation plays a critical role during development, particularly in repressing retrotransposons. The mammalian methylation landscape is dependent on the combined activities of the canonical maintenance enzyme Dnmt1 and the de novo Dnmts, 3a and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88e4b7af8005f3f8745559b53e7b4eaa
Autor:
Kendell Clement, Chuck Haggerty, Stefan Aigner, Hongcang Gu, Alexander Meissner, Inna Lipchina, Anthony Anselmo, Steven P. Gygi, Justin Brumbaugh, Fei Ji, John L. Pulice, Mattia F. M. Gerli, Katie J. Clowers, Aaron J. Huebner, Inés Rabano Jiménez, En-Ching Luo, Ruslan I. Sadreyev, Bruno Di Stefano, Konrad Hochedlinger, Jocelyn Charlton, Marit A.C. de Kort, Gene W. Yeo
Publikováno v:
Cell Stem Cell
Cell stem cell, vol 25, iss 5
Cell stem cell, vol 25, iss 5
Post-transcriptional mechanisms have the potential to influence complex changes in gene expression, yet their role in cell fate transitions remains largely unexplored. Here, we show that suppression of the RNA helicase DDX6 endows human and mouse pri