Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Chuanzeng Cao"'
Autor:
Irene Tang, Lauren Schwimmer, Shenda Gu, Wei Wei Prior, Hieu Van Tran, Allan Chan, Anna McClain, Christopher C. Fraser, Chunyan Sun, Meimei Si, Guijiang Wang, Yunxia Zhao, Ning Zhang, Jiayu Fu, Mengxin Liu, Chuanzeng Cao, Shihao Chen
Publikováno v:
Frontiers in Drug Discovery, Vol 3 (2023)
Cell surface molecules PD-L1 and CD47 are potent inhibitors of adaptive and innate anti-cancer immunity. We sought to generate a safe, therapeutic, bispecific antibody specifically targeting, and blocking both PD-L1 and CD47 inhibitory activity. Nove
Externí odkaz:
https://doaj.org/article/ea6e81876bdd4c2797c21b733c8f5700
Autor:
Irene Tang, Lauren Schwimmer, Monica Jin, Shenda Gu, Wei Wei Prior, Arianne Capacio, Hieu V. Tran, Allan Chan, Anna McClain, Shihao Chen, Chuanzeng Cao, Xiaoran Wu, Yanling Xu, Dongmei Guan, Xi Chen, Xianli Su
Publikováno v:
Cancer Research. 82:3504-3504
Cytokines are potent stimulators of the immune system and have long been investigated and used as therapeutics to treat cancer. However, free cytokines have short half-life and the lack of tumor targeting often results in systemic toxicity. IL-15 is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b9c2894a3cec74b66d166369a3a2f80
https://doi.org/10.1158/1538-7445.am2022-3504
https://doi.org/10.1158/1538-7445.am2022-3504
Autor:
Irene Tang, Lauren Schwimmer, Shenda Gu, Wei Wei Prior, Hieu V. Tran, Allan Chan, Anna McClain, Shihao Chen, Chuanzeng Cao, Chunyan Sun, Meimei Si, Guijiang Wang
Publikováno v:
Cancer Research. 82:2894-2894
Upregulation of CD47, a “Do Not Eat Me” signal, is observed in nearly all solid and hematological malignancies. Engagement of CD47 on tumor cells with SIRPα on macrophages inhibits phagocytosis of tumor cells. Anti-CD47 antibodies block the CD47
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43fa706132a8d75f31d0b35fc5f16a20
https://doi.org/10.1158/1538-7445.am2022-2894
https://doi.org/10.1158/1538-7445.am2022-2894
Autor:
Junjie, Yang, Wenchao, Fan, Han, Xiao, Chunhong, Guan, Chuanzeng, Cao, Haifeng, Shao, Weihong, Jiang, Sheng, Yang
Publikováno v:
Sheng wu gong cheng xue bao = Chinese journal of biotechnology. 26(10)
Genome shuffling methods were explored for Bacillus subtilis strain molecular breeding. Recycling protoplast fusion, recycling transformation and recycling universal transduction were used for genome shuffling in B. subtilis. Four strains with differ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d19efd9bf851ee10476e961540556050
https://pubmed.ncbi.nlm.nih.gov/21218626
https://pubmed.ncbi.nlm.nih.gov/21218626