Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Chuanyun Luo"'
Publikováno v:
Biochemistry. 48:8976-8984
Bacterial type I signal peptidase (SPase I), an essential membrane-bound endopeptidase with a unique Ser/Lys dyad mechanism, is being investigated as a potential novel antibiotic target. We present here binding and inhibition assays along with crysta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a48d9dd22ab0cd6544a282d1beb1703
https://doi.org/10.1021/bi9009538
https://doi.org/10.1021/bi9009538
Autor:
Bart Scherens, Ning Lan, Steeve Veronneau, Anna Astromoff, Matt Curtiss, Ronald W. Davis, Jeffrey N. Strathern, Marleen Voet, Johannes H. Hegemann, Ankuta Lucau-Danila, Petra Ross-Macdonald, Adam M. Deutschbauer, Françoise Foury, Greg Schimmack, Daniel D. Shoemaker, Karen Davis, Rhonda Bangham, Darlene LaBonte, Christopher J. Roberts, Zelek S. Herman, Patrick Flaherty, Stefano Campanaro, Patrice Menard, Michael Snyder, Teresa R. Ward, Adam P. Arkin, Howard Bussey, Linda Riles, Yonghong Yang, Grace Yen, Guri Giaever, K. D. Entian, Kexin Yu, Elaine M. Youngman, Sharon Sookhai-Mahadeo, Jef D. Boeke, Reginald Storms, Daniel F. Jaramillo, Giorgio Valle, José L. Revuelta, Sally Dow, Mark Johnston, Matthias Rose, Mohamed El Bakkoury, Deanna Gotte, Hong Liao, Elizabeth A. Winzeler, Brenda Shafer, Marc Lussier, Chuanyun Luo, Siew Loon Ooi, Peter Philippsen, Angela M. Chu, Guido Volckaert, Rong Mao, Peter Kötter, Keith Anderson, Ching Yun Wang, Julie Wilhelmy, Ulrich Güldener, Li Ni, Lucy Y. Liu, Mark Gerstein, David C. Lamb, Steven L. Kelly, Carla Connelly, Diane E. Kelly, Svenja Hempel, Rocío Benito, David J. Garfinkel, Bruno André, Hong Liang, Sophie Brachat
Publikováno v:
Nature. 418:387-391
Determining the effect of gene deletion is a fundamental approach to understanding gene function. Conventional genetic screens exhibit biases, and genes contributing to a phenotype are often missed. We systematically constructed a nearly complete col
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57bc06ae739927da5c4b01c8dabd24f4
https://doi.org/10.1038/nature00935
https://doi.org/10.1038/nature00935
Autor:
Jian Liu, Malcolm G. P. Page, Peter A. S. Smith, Jodie K. Chin, Floyd E. Romesberg, Chuanyun Luo, Mark Paetzel
Publikováno v:
Journal of the American Chemical Society. 133(44)
Glycosylation of natural products, including antibiotics, often plays an important role in determining their physical properties and their biological activity, and thus their potential as drug candidates. The arylomycin class of antibiotics inhibits
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae9ffee003cc053dd0532e4f77a83c2d
https://pubmed.ncbi.nlm.nih.gov/21999324
https://pubmed.ncbi.nlm.nih.gov/21999324
Publikováno v:
Biochemistry; 9/29/2009, Vol. 48 Issue 38, p8976-8984, 9p