Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Chuantao Tu"'
Publikováno v:
Frontiers in Nutrition, Vol 11 (2024)
BackgroundMetabolic dysfunction-associated fatty liver disease (MAFLD) is presently the most prevalent chronic liver disorder globally that is closely linked to obesity, dyslipidemia metabolic syndrome, and type 2 diabetes mellitus (T2DM). Its pathog
Externí odkaz:
https://doaj.org/article/93524106eed8433c8de489f6b73d0c88
Autor:
Philip A. Waghorn, Diego S. Ferreira, Derek J. Erstad, Nicholas J. Rotile, Ricard Masia, Chloe M. Jones, Chuantao Tu, Mozhdeh Sojoodi, Yin-ching I. Chen, Franklin Schlerman, Jeremy Wellen, Robert V. P. Martinez, Kenneth K. Tanabe, Bryan C. Fuchs, Peter Caravan
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Non-alcoholic steatohepatitis (NASH) is an increasing cause of chronic liver disease characterized by steatosis, inflammation, and fibrosis which can lead to cirrhosis, hepatocellular carcinoma, and mortality. Quantitative, noninvasive metho
Externí odkaz:
https://doaj.org/article/327b39d031bd46df9de3f4c4aba0cf0e
Autor:
Philip A. Waghorn, Diego S. Ferreira, Derek J. Erstad, Nicholas J. Rotile, Ricard Masia, Chloe M. Jones, Chuantao Tu, Mozhdeh Sojoodi, Yin-ching I. Chen, Franklin Schlerman, Jeremy Wellen, Robert V. P. Martinez, Kenneth K. Tanabe, Bryan C. Fuchs, Peter Caravan
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-2 (2021)
Externí odkaz:
https://doaj.org/article/5dff62519d184cbbbad8e11434fc02ef
Publikováno v:
Frontiers in Medicine, Vol 7 (2020)
This study aimed to investigate the beneficial effects of myricetin in a diet-induced nonalcoholic steatohepatitis (NASH) model and the underlying mechanism. C57BL/6J mice were fed a standard chow or the choline-deficient, L-amino acid-defined, high-
Externí odkaz:
https://doaj.org/article/c5ee6189cb0c46e2bebf6b96ffd71cee
Autor:
Derek J. Erstad, Christian T. Farrar, Sarani Ghoshal, Ricard Masia, Diego S. Ferreira, Yin‐Ching Iris Chen, Ji‐Kyung Choi, Lan Wei, Phillip A. Waghorn, Nicholas J. Rotile, Chuantao Tu, Katherine A. Graham‐O'Regan, Mozhdeh Sojoodi, Shen Li, Yang Li, Guogiang Wang, Kathleen E. Corey, Yat Sun Or, Lijuan Jiang, Kenneth K. Tanabe, Peter Caravan, Bryan C. Fuchs
Publikováno v:
Hepatology Communications, Vol 2, Iss 7, Pp 821-835 (2018)
We examined a novel farnesoid X receptor agonist, EDP‐305, for its antifibrotic effect in bile duct ligation (BDL) and choline‐deficient, L‐amino acid‐defined, high‐fat diet (CDAHFD) models of hepatic injury. We used molecular magnetic reso
Externí odkaz:
https://doaj.org/article/3b4760b0fefd4d1697564907fb1c9f1f
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
This study aims to investigate the protective effects of morin hydrate (MH) against acute liver injury induced by carbon tetrachloride (CCl4) in mice and to elucidate the possible molecular mechanism of action. Mice were pretreated with MH (50 mg/kg
Externí odkaz:
https://doaj.org/article/25c97b28214b421798055f7aca679756
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
At present, there are no effective antifibrotic drugs for patients with chronic liver disease; hence, the development of antifibrotic therapies is urgently needed. Here, we performed an experimental and translational study to investigate the potentia
Externí odkaz:
https://doaj.org/article/26a7bc68b52546fb8ab9039308afe81c
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Placental growth factor (PlGF), a member of the vascular endothelial growth factor (VEGF) family, mediates wound healing and inflammatory responses, exerting an effect on liver fibrosis and angiogenesis; however, the precise mechanism remains unclear
Externí odkaz:
https://doaj.org/article/0dd57dd6b27f4460b364e88eef7520ec
Autor:
Mozhdeh Sojoodi, Derek J. Erstad, Franklin J. Schlerman, Peter Caravan, Chuantao Tu, Nicholas J. Rotile, Kenneth K. Tanabe, Bryan C. Fuchs, Ricard Masia, Diego dos Santos Ferreira, Jeremy W. Wellen, Philip A. Waghorn, Yin-ching I. Chen, Chloe M. Jones, Robert V. Martinez
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports
Scientific Reports
Non-alcoholic steatohepatitis (NASH) is an increasing cause of chronic liver disease characterized by steatosis, inflammation, and fibrosis which can lead to cirrhosis, hepatocellular carcinoma, and mortality. Quantitative, noninvasive methods for ch
Autor:
Peter Caravan, Nicholas J. Rotile, Franklin J. Schlerman, Chuantao Tu, Yin-ching I. Chen, Ricard Masia, Derek J. Erstad, Diego dos Santos Ferreira, Jeremy W. Wellen, Philip A. Waghorn, Bryan C. Fuchs, Kenneth K. Tanabe, Chloe M. Jones, Mozhdeh Sojoodi, Robert V. Martinez
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-2 (2021)