Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Chuanrui Ma"'
Autor:
Zhihao Liu, Xiyun Bian, Lan Li, Li Liu, Chao Feng, Ying Wang, Jingyu Ni, Sheng Li, Dading Lu, Yanxia Li, Chuanrui Ma, Tian Yu, Xiaolin Xiao, Na Xue, Yuxiang Wang, Chunyan Zhang, Xiaofang Ma, Xiumei Gao, Xiaohui Fan, Xiaozhi Liu, Guanwei Fan
Publikováno v:
Advanced Science, Vol 11, Iss 34, Pp n/a-n/a (2024)
Abstract Myocardial infarction (MI) triggers a poor ventricular remodeling response, but the underlying mechanisms remain unclear. Here, the authors show that sentrin‐specific protease 1 (SENP1) is downregulated in post‐MI mice and in patients wi
Externí odkaz:
https://doaj.org/article/01008cc38a86416785ef581069395e74
Autor:
Zhihao Liu, Xiaozhi Liu, Li Liu, Ying Wang, Jie Zheng, Lan Li, Sheng Li, Han Zhang, Jingyu Ni, Chuanrui Ma, Xiumei Gao, Xiyun Bian, Guanwei Fan
Publikováno v:
Journal of Pharmaceutical Analysis, Vol 13, Iss 2, Pp 170-186 (2023)
Small ubiquitin-related modifier (SUMOylation) is a dynamic post-translational modification that maintains cardiac function and can protect against a hypertrophic response to cardiac pressure overload. However, the function of SUMOylation after myoca
Externí odkaz:
https://doaj.org/article/c7bcf14449bc4efb9f532ee1232e2d78
Autor:
Jingyu Ni, Hao Zhang, Xiaodan Wang, Zhihao Liu, Tong Nie, Lan Li, Jing Su, Yan Zhu, Chuanrui Ma, Yuting Huang, Jingyuan Mao, Xiumei Gao, Guanwei Fan
Publikováno v:
Cell Death and Disease, Vol 13, Iss 12, Pp 1-12 (2022)
Abstract The failing heart is characterized by an increase in glucose uptake and glycolytic rates that is not accompanied by a concomitant increase in glucose oxidation. Lower coupling of glucose oxidation to glycolysis possibly owes to unchanged or
Externí odkaz:
https://doaj.org/article/ff3b455594ed4c14af3ca200a49b107b
Autor:
Shu Yang, Jiaqing Xiang, Chuanrui Ma, Guangyan Yang, Xinyu Wang, Hanyong Liu, Guanwei Fan, Lin Kang, Zhen Liang
Publikováno v:
Cell Reports, Vol 42, Iss 4, Pp 112367- (2023)
Summary: Transforming growth factor β (TGF-β) is the primary factor that drives fibrosis in most forms of chronic kidney disease. The aim of this study was to identify endogenous regulators of TGF-β signaling and fibrosis. Here, we show that tubul
Externí odkaz:
https://doaj.org/article/21b743ff816b4518860d90c994cdbac3
Autor:
Chuanrui Ma, Xinyu Wang, Jing Zhang, Yun Zhao, Yunqing Hua, Chao Zhang, Guobin Zheng, Guangyan Yang, Jianli Guan, Huahuan Li, Meng Li, Lin Kang, Jiaqing Xiang, Guanwei Fan, Shu Yang
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Nonalcoholic fatty liver disease (NAFLD) is defined as liver disease in which more than 5% of hepatocytes are steatotic with little or no alcohol consumption. NAFLD includes benign nonalcoholic fatty liver (NAFL) and nonalcoholic steatohepatitis (NAS
Externí odkaz:
https://doaj.org/article/2fb34f33a647460d913b1e20d205e14b
Autor:
Yunqing Hua, Jing Zhang, Qianqian Liu, Jing Su, Yun Zhao, Guobin Zheng, Zhihui Yang, Danping Zhuo, Chuanrui Ma, Guanwei Fan
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
Increasing attention is now being paid to the important role played by autophagic flux in maintaining normal blood vessel walls. Endothelial cell dysfunction initiates the development of atherosclerosis. In the endothelium, a variety of critical trig
Externí odkaz:
https://doaj.org/article/310e46453d67454da161315b3bb1ba3a
Autor:
Chuanrui Ma, Jiaqing Xiang, Guixiao Huang, Yaxi Zhao, Xinyu Wang, Han Wu, Kewei Jiang, Zhen Liang, Lin Kang, Guangyan Yang, Shu Yang
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Background and purpose: FXR is a promising target for the treatment of human cholestatic liver disease (CLD). SIRT1 is a deacetylase which promotes FXR activity through deacetylating FXR. Pterostilbene (PTE) is an activator of SIRT1. However, the rol
Externí odkaz:
https://doaj.org/article/2f6b7998610b4b7dbe7599cf68119b5f
Autor:
Juntao Zhang, Chao Zhang, Aifeng Liu, Qiang Ji, Lixia Ren, Chuanrui Ma, Hengyu Zhang, Chaochao Wu, Donglin Zhang, Man Shang, Feng He
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Background: Icariin, a traditional Chinese medicine, plays a protective role in the treatment of exercise fatigue. Zinc, a trace element, plays an important role in the reproductive system. Therefore, we aimed to synthesize an Icariin-Zinc complex (b
Externí odkaz:
https://doaj.org/article/5be99904b35f4fb5a772007b2b8e7091
Autor:
Chuanrui Ma, Zhongyan Wang, Ronglin Xia, Lingling Wei, Chao Zhang, Jing Zhang, Linna Zhao, Han Wu, Lin Kang, Shu Yang
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 137, Iss , Pp 111344- (2021)
Obesity and associated metabolic associated fatty liver diseases (MAFLD) are strongly associated with dysfunction of glucose and lipid metabolism. AMPKα and PPARα are key regulators in the lipid and glucose homeostasis, indicating that novel agents
Externí odkaz:
https://doaj.org/article/4301d77195e84dccb2bd97c3c5f98002
Autor:
Ying Liu, Zhuo Wei, Ye Zhang, Xingzhe Ma, Yuanli Chen, Miao Yu, Chuanrui Ma, Xiaoju Li, Youjia Cao, Jian Liu, Jihong Han, Xiaoxiao Yang, Yajun Duan
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 12, Pp 2287-2296 (2018)
Production of 25-hydroxycholesterol (25HC), a potent inhibitor of viral infection, is catalyzed by cholesterol 25-hydroxylase (CH25H). We previously reported that 25HC induced CH25H expression in a liver X receptor (LXR)-dependent manner, implying th
Externí odkaz:
https://doaj.org/article/cd46c12aee2d4f6db24c0568fca24b30