Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Chuanling Zhang"'
Autor:
Francesco Puzzo, Chuanling Zhang, Bethany Powell Gray, Feijie Zhang, Bruce A. Sullenger, Mark A. Kay
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 31, Iss , Pp 383-397 (2023)
Adeno-associated viruses (AAVs) are commonly used for in vivo gene therapy. Nevertheless, the wide tropism that characterizes these vectors limits specific targeting to a particular cell type or tissue. Here, we developed new chemically modified AAV
Externí odkaz:
https://doaj.org/article/2cb14785ab9043a29a90dad688519651
Autor:
Wenjing Chen, Chunyan He, Han Yang, Wen Shu, Zelin Cui, Rong Tang, Chuanling Zhang, Qingzhong Liu
Publikováno v:
BMC Microbiology, Vol 20, Iss 1, Pp 1-12 (2020)
Abstract Background The data on the prevalence of resistance to mupirocin (MUP), fusidic acid (FA) and retapamulin (RET) in methicillin-resistant Staphylococcus aureus (MRSA) from China are still limited. This study aimed to examine these three antib
Externí odkaz:
https://doaj.org/article/f42ead42cae14512986bce82104e75b8
Publikováno v:
Agronomy, Vol 12, Iss 3, p 566 (2022)
Grain quality is a critical component of high-yielding varieties to ensure acceptance by an ever-increasing population and living standards. During the past years, several photorespiration bypasses have been introduced into C3 plants, among which our
Externí odkaz:
https://doaj.org/article/6279a47fb1ff46469223de2291d9e9ac
Autor:
Han Yang, Su Xu, Kaifeng Huang, Xiaogang Xu, Fupin Hu, Chunyan He, Wen Shu, Zhiyan Wang, Fang Gong, Chuanling Zhang, Qingzhong Liu
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Antibiotics have been described to modulate bacterial virulence gene expression. This study aimed to assess the changes caused by anti-Staphylococcus agents in the transcription of leucocidin ED (lukED) gene of Staphylococcus aureus strain Newman in
Externí odkaz:
https://doaj.org/article/33ecc8021e264654bfd39b144176f538
Autor:
Huanqiang Zhao, Su Xu, Han Yang, Chunyan He, Xiaogang Xu, Fupin Hu, Wen Shu, Fang Gong, Chuanling Zhang, Qingzhong Liu
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
The toxic shock syndrome toxin-1 (TSST-1), encoded by tst gene, has been proposed to cause staphylococcal toxic shock syndrome (TSS) in a susceptible host, which highlights the need to evaluate the level of tst gene expression and molecular genetic c
Externí odkaz:
https://doaj.org/article/0bc1d7b825dd4d93b4436b9bc41cf5b4
Publikováno v:
Data in Brief, Vol 7, Iss , Pp 77-80 (2016)
RGD tripeptide is a specific, high-affinity ligand for integrin, which is highly expressed in cancer cells. We previously reported that cRGD chemically modified AAV2 (AAV2N587+1/azido+RGD) showed significantly enhanced infectivity compared to RGD gen
Externí odkaz:
https://doaj.org/article/20e5740aa92d427f8fb01483df725d03
Publikováno v:
Polymers, Vol 11, Iss 5, p 820 (2019)
Gambogenic acid (GNA) has been demonstrated with outstanding antitumor activity as a potential antitumor drug in recent years. However, the low solubility and deficient bioavailability of GNA seriously hinder its practical application in the clinic a
Externí odkaz:
https://doaj.org/article/6091ce3fd228470b905b49e21c925646
Autor:
Chuanling Zhang, Liang Guo, Xu Chu, Limeng Shen, Yuanyu Guo, Huali Dong, Jianfeng Mao, Stijn van der Veen
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0156704 (2016)
The Panton-Valentine leukocidin (PVL) genes of methicillin-resistant Staphylococcus aureus (MRSA) have previously been associated with severe infections. Here, the impact of the PVL genes on severity of disease and clinical outcome of patients with h
Externí odkaz:
https://doaj.org/article/ba1069f445534ff681a98a3cc866b454
Autor:
Tianzhuo Yao, Xueying Zhou, Chuanling Zhang, Xiaojuan Yu, Zhenyu Tian, Lihe Zhang, Demin Zhou
Publikováno v:
Molecules, Vol 22, Iss 7, p 1155 (2017)
Adeno-associated virus (AAV) is one of the most extensively studied and utilized viral vectors in clinical gene transfer research. However, the serum instability and immunogenicity of AAV vectors significantly limit their application. Here, we endeav
Externí odkaz:
https://doaj.org/article/ba31bd77f0334110848b9a9ac90c43ac
Autor:
Yingbo Li, Jinxi Wang, Xing Gao, Weihua Han, Yongxiang Zheng, Huan Xu, Chuanling Zhang, Qiuchen He, Lihe Zhang, Zhongxin Li, Demin Zhou
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e113186 (2014)
Although EGFR-targeted therapy has been beneficial to colorectal cancer patients, several studies have showed this clinical benefit was restricted to patients with wild-type KRAS exon 2 colorectal cancer. Therefore, it is crucial to explore efficient
Externí odkaz:
https://doaj.org/article/e3debbcc1cff460f88773af6521da54e