Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Chuankai Chen"'
Publikováno v:
Cells, Vol 13, Iss 12, p 1061 (2024)
Serine/threonine kinase AKT isoforms play a well-established role in cell metabolism and growth. Most pancreatic adenocarcinomas (PDACs) harbor activation mutations of KRAS, which activates the PI3K/AKT signaling pathway. However, AKT inhibitors are
Externí odkaz:
https://doaj.org/article/97da35a4a422476ebc5694cf615867be
Autor:
Yulong He, Fujing Zhang, Xuelian Liu, Ralf H. Adams, Junhao Hu, Zhihai Qin, Qi Xiao, Zhongzhou Yang, Wencan Han, Luqing Zhang, Zhiliang Sun, Taotao Li, Wei Sun, Xiao Li, Katsuhiro Kato, Chuankai Chen, Haijuan Jiang, Xiang Gao
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 40:958-972
Objective: Angiocrine factors, mediating the endothelial-mural cell interaction in vascular wall construction as well as maintenance, are incompletely characterized. This study aims to investigate the role of endothelial cell–derived FSTL1 (follist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a276a47f6279fce176b1d91a77bcf0f
https://doi.org/10.1161/atvbaha.119.313901
https://doi.org/10.1161/atvbaha.119.313901
Autor:
Fujing Zhang, Zhihai Qin, Zhongzhou Yang, Wencan Han, Chuankai Chen, Luqing Zhang, Ralf H. Adams, Yulong He, Xuelian Liu, Xiao Li, Xiang Gao, Haijuan Jiang, Wei Sun, Qi Xiao, Katsuhiro Kato
Angiocrine factors, mediating the endothelial-mural cell interaction in vascular wall construction as well as maintenance, are incompletely characterized. Here we show that loss of follistatin-like protein 1 (FSTL1) in endothelial cells (Fstl1ECKO) l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::593169370f0c74a6c4febd1ff3da577b
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Quantifying the contribution of individual molecular components to complex cellular processes is a grand challenge in systems biology. Here we establish a general theoretical framework (Functional Decomposition of Metabolism, FDM) to quantif
Externí odkaz:
https://doaj.org/article/b4dc6275337448f4af01f13cbc5a41b6
Autor:
Eric W. Getz, V. Celeste Lanclos, Conner Y. Kojima, Chuankai Cheng, Michael W. Henson, Max Emil Schön, Thijs J. G. Ettema, Brant C. Faircloth, J. Cameron Thrash
Publikováno v:
mSystems, Vol 8, Iss 3 (2023)
ABSTRACT Bacterioplankton of the SAR11 clade are the most abundant marine microorganisms and consist of numerous subclades spanning order-level divergence (Pelagibacterales). The assignment of the earliest diverging subclade V (a.k.a. HIMB59) to the
Externí odkaz:
https://doaj.org/article/2187e11a17a1498db470b521e566a768
Autor:
Emily R. Savoie, V. Celeste Lanclos, Michael W. Henson, Chuankai Cheng, Eric W. Getz, Shelby J. Barnes, Douglas E. LaRowe, Michael S. Rappé, J. Cameron Thrash
Publikováno v:
mSystems, Vol 6, Iss 3 (2021)
Marine microbial communities are teeming with understudied taxa due to the sheer numbers of species in any given sample of seawater. One group, the OM252 clade of Gammaproteobacteria
Externí odkaz:
https://doaj.org/article/a2e37de97edb4fb998d3df725e8532e6
Autor:
Chuankai Cheng, Edward J O'Brien, Douglas McCloskey, Jose Utrilla, Connor Olson, Ryan A LaCroix, Troy E Sandberg, Adam M Feist, Bernhard O Palsson, Zachary A King
Publikováno v:
PLoS Computational Biology, Vol 15, Iss 6, p e1007066 (2019)
Growth rate and yield are fundamental features of microbial growth. However, we lack a mechanistic and quantitative understanding of the rate-yield relationship. Studies pairing computational predictions with experiments have shown the importance of
Externí odkaz:
https://doaj.org/article/4a2feab96b1348f18230f23cfb01b673