Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Chuangpeng Shen"'
Autor:
Lei Zhang, Jiabing Chen, Xiaoying Yang, Chuangpeng Shen, Jiawen Huang, Dong Zhang, Naihua Liu, Chaonan Liu, Yadi Zhong, Yingjian Chen, Kaijia Tang, Jingyi Guo, Tianqi Cui, Siwei Duan, Jiayu Li, Shangyi Huang, Huafeng Pan, Huabing Zhang, Xiaoqiang Tang, Yongsheng Chang, Yong Gao
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-16 (2024)
Abstract A lasting imbalance between fatty acid synthesis and consumption leads to non-alcoholic fatty liver disease (NAFLD), coupled with hepatitis and insulin resistance. Yet the details of the underlying mechanisms are not fully understood. Here,
Externí odkaz:
https://doaj.org/article/d8de1c3c1c394317ae7c9862f20a043f
Autor:
Yi Zheng, Jian Zhao, Deyu Miao, Tingting Xu, Liziniu Wang, Changhui Liu, Yong Gao, Lili Yu, Chuangpeng Shen
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 164, Iss , Pp 114957- (2023)
Non-alcoholic fatty liver disease (NAFLD) is one of the most frequent health issues. The improvement of NAFLD is related to the activation of the farnesoid X receptor (FXR). Typhaneoside (TYP) is the main component of Typha orientalis Presl, which pl
Externí odkaz:
https://doaj.org/article/564002b65d5a43528e67e55d915de4da
Autor:
Meng Song, Zijun Chen, Ruian Qiu, Tingwei Zhi, Wenmin Xie, Yingya Zhou, Nachuan Luo, Fuqian Chen, Fang Liu, Chuangpeng Shen, Sheng Lin, Fengxue Zhang, Yong Gao, Changhui Liu
Publikováno v:
Redox Biology, Vol 55, Iss , Pp 102404- (2022)
The excessive accumulation of bile acids (BA) in hepatocytes can trigger inflammatory response and recruit macrophages, thereby accelerating cholestatic liver injury. The crosstalk between hepatocytes and macrophages has been recently implicated in t
Externí odkaz:
https://doaj.org/article/fe1db590517d45359fcee2c55854e7b0
Autor:
Zhisen Pan, Jingyi Guo, Kaijia Tang, Yanling Chen, Xun Gong, Yingjian Chen, Yadi Zhong, Xiaoxia Xiao, Siwei Duan, Tianqi Cui, Xiumei Wu, Yanhua Zhong, Xiaoying Yang, Chuangpeng Shen, Yong Gao
Publikováno v:
Journal of Agricultural and Food Chemistry. 70:14220-14234
Alcoholic liver disease (ALD) is a serious worldwide health problem. Ginsenoside Rc is a major active ingredient isolated from
Autor:
Chuangpeng Shen, Zhisen Pan, Xiaojie Wu, Chong Zhong, Qiao Li, Yuqi Si, Changhui Liu, Haitao Tu, Zhijun Deng, Zhangzhi Zhu, Jiewen Guo, Xiaoyi Xin, Min Liu
Publikováno v:
Journal of Chromatographic Science. 60:478-485
A simple, rapid and sensitive analytical method was developed for the determination of toosendanin in rat plasma using liquid chromatography tandem mass spectrometry (LC–MS/MS). Andrographolide was selected as the internal standard, and the plasma
Publikováno v:
International journal of clinical pharmacology and therapeutics. 60(11)
Anti-thyroid drugs (ATDs), such as methimazole (MMI) and propylthiouracil (PTU), are the most common treatment options for hyperthyroidism. Although effective, well-known adverse effects include agranulocytosis, toxic hepatitis, vasculitis, and arthr
Autor:
Gangyi Chen, Liangliang Wang, Yuanyuan Luo, Shuifu Tang, Xun Zhuang, Chuangpeng Shen, Duanhua Ma, Liangyou Zhang, Ying Li, Haitao Tu, Zhengkun Hou, Huan Lu
Publikováno v:
Bioengineered, Vol 12, Iss 1, Pp 6538-6558 (2021)
Bioengineered
article-version (VoR) Version of Record
Bioengineered
article-version (VoR) Version of Record
Chronic renal failure (CRF) threatens human health greatly and attracts worldwide concerns of health professionals in the public health sector. In our preliminary study, we found that Compound capsule (Shengqing Jiangzhuo Capsule, SQJZJN) had a signi
Autor:
Zehong Yang, Chen Yang, Zhao Gao, Ling Hu, Nannan Sun, Yuanyuan Yu, Chuangpeng Shen, Wei Miao, Kevin W. Williams, Yongsheng Chang, Xiaojie Wu, Yong Gao, Chong Zhong, Lei Zhang, Weihang Gao, Changhui Liu, Xiaoying Yang
Publikováno v:
Gut
ObjectiveImpaired hepatic fatty acids oxidation results in lipid accumulation and redox imbalance, promoting the development of fatty liver diseases and insulin resistance. However, the underlying pathogenic mechanism is poorly understood. Krüppel-l
Autor:
Xiaoyi Xin, Meijing Liu, Haoxiang Wu, Zhangzhi Zhu, Zehong Yang, Huixuan Li, Changhui Liu, Li Saimei, Junmei Zhang, Chuangpeng Shen, Shaoxiang Xian, Wen Luo, Min Liu, Wentao Duan, Xueying Liu
Publikováno v:
Oxidative Medicine and Cellular Longevity, Vol 2020 (2020)
Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity
Chrysophanol, a primary active ingredient of Cassia mimosoides Linn or Rhei radix et rhizoma, has various pharmacological properties, including anticancer, antidiabetic, and anti-inflammatory, as well as blood lipid regulation. However, whether chrys
Autor:
Chuangpeng Shen, Jueyu Wang, Chen-Chen Zhu, Xingan Huang, Guohui Zhang, Meng Song, Zhao Chen, Changhui Liu, Suiqing Mi, Chao-Zhan Lin, Meijing Liu, Yong Gao
Publikováno v:
Antioxidantsredox signaling. 33(2)
Aims: Acetaminophen (APAP) overdose leads to acute liver injury by inducing hepatic mitochondrial oxidative stress and inflammation. However, the molecular mechanisms involved are still unclear. Farnesoid X receptor (FXR) serves as a therapeutic targ