Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Chuangeng Zhang"'
Autor:
Thomas W. Comollo, Xinle Zou, Chuangeng Zhang, Divya Kesters, Thomas Hof, Kevin J. Sampson, Robert S. Kass
Publikováno v:
Channels, Vol 16, Iss 1, Pp 173-184 (2022)
The congenital long QT syndrome (LQTS), one of the most common cardiac channelopathies, is characterized by delayed ventricular repolarization underlying prolongation of the QT interval of the surface electrocardiogram. LQTS is caused by mutations in
Externí odkaz:
https://doaj.org/article/58436b77c67d45cc9fb45c2f86705f5e
Publikováno v:
Neuroscience. 514:25-37
Cellular morphology and synaptic configuration are key determinants of neuronal function and are often modified under pathological conditions. In the first nucleus of the central auditory system, the cochlear nucleus (CN), principal bushy neurons spe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65ad558d7e83e275057cd337d5c528b9
https://doi.org/10.1016/j.neuroscience.2023.01.037
https://doi.org/10.1016/j.neuroscience.2023.01.037
Publikováno v:
J Neurosci
Calretinin (CR) is a major calcium binding protein widely expressed in the CNS. However, its synaptic function remains largely elusive. At the auditory synapse of the endbulb of Held, CR is selectively expressed in different subtypes. Combining elect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e530817239b0c4d1398f59b5128372d1
https://doi.org/10.1523/jneurosci.1773-21.2022
https://doi.org/10.1523/jneurosci.1773-21.2022
Autor:
Yong Wang, Chuangeng Zhang, Shengyin Lin, Benjamin J. Seicol, Meijian Wang, Ruili Xie, Robert W. Ariss
Publikováno v:
The Journal of physiology. 599(6)
Key points Sound information is transmitted by different subtypes of spiral ganglion neurons (SGN) from the ear to the brain. Selective damage of SGN peripheral synapses (cochlear synaptopathy) is widely recognized as one of the primary mechanisms of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e060fafa06885ca9f327b2b09f66215
https://pubmed.ncbi.nlm.nih.gov/33517580
https://pubmed.ncbi.nlm.nih.gov/33517580
Autor:
Robert W. Ariss, Benjamin J. Seicol, Chuangeng Zhang, Meijian Wang, Shengyin Lin, Yong Wang, Ruili Xie
SUMMARYSound information is transmitted from the cochlea to the brain by different subtypes of spiral ganglion neurons (SGN), which show varying degrees of vulnerbility under pathological conditions. It remains unclear how information from these SGNs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b6fb56eb0cfd84d81774a44a2212332
https://doi.org/10.1101/2020.06.09.142737
https://doi.org/10.1101/2020.06.09.142737
Publikováno v:
Cardiac Repolarization ISBN: 9783030226718
The physiology of the heart is controlled by an indigenous electrical system that regulates heart rhythm and contractile activity. The timing of cardiac electrical events is critical to proper heart function, and key to this activity is duration of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7093d9117ae15c10abf03d8bdd95d467
https://doi.org/10.1007/978-3-030-22672-5_1
https://doi.org/10.1007/978-3-030-22672-5_1
Autor:
Zongyun Chen, Zhijian Cao, Weishan Yang, Jing Yao, Chuangeng Zhang, Xinxin Li, Yingliang Wu, Yange Lang, Zili Xie, Wenxin Li, Jing Feng, Jing Chen
Publikováno v:
Biochemical Journal. 473:1257-1266
Scorpions are insensitive to their own venoms, which contain various neurotoxins specific for mammalian or insect ion channels, whose molecular mechanism remains unsolved. Using MmKv1, a potassium channel identified from the genome of the scorpion Me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae53388b515f3eb2e28922ce24197a4b
https://doi.org/10.1042/bcj20160178
https://doi.org/10.1042/bcj20160178
Publikováno v:
International Journal of Biological Macromolecules. 79:504-510
Peptides with Ascaris-type fold are a new kind of toxins founded from venomous animals recently. Functionally, these unique toxin peptides had been identified as potent protease inhibitors, which was similar to other known Ascaris-type peptides from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a673bc6baa024ab813fd011b3803a16b
https://doi.org/10.1016/j.ijbiomac.2015.05.027
https://doi.org/10.1016/j.ijbiomac.2015.05.027
Autor:
Zongyun Chen, Zhijian Cao, Bin Wang, Chuangeng Zhang, Weishan Yang, Yingliang Wu, Jun Hu, Wenxin Li, Zili Xie, Jing Chen, Youtian Hu
Publikováno v:
Peptides. 71
The KCNQ1/KCNE1 channel (IKs) plays important roles in the physiological and pathological process of heart, but no potent peptide acting on this channel has been reported. In this work, we found that the natural scorpion venom hardly inhibited KCNQ1/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b09ead95c9e4d4df1701dc36a2593dff
https://pubmed.ncbi.nlm.nih.gov/26188173
https://pubmed.ncbi.nlm.nih.gov/26188173
Autor:
Chuangeng Zhang, Zili Xie, Xinxin Li, Jing Chen, Jing Feng, Yange Lang, Weishan Yang, Wenxin Li, Zongyun Chen, Jing Yao, Zhijian Cao, Yingliang Wu
Publikováno v:
Biochemical Journal; 5/1/2016, Vol. 473 Issue 9, p1257-1266, 10p