Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Chuangao Xie"'
Autor:
Dario Garcia-Carracedo, Chih-Chieh Yu, Nathan Akhavan, Stuart A Fine, Frank Schönleben, Naoki Maehara, Dillon C Karg, Chuangao Xie, Wanglong Qiu, Robert L Fine, Helen E Remotti, Gloria H Su
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0120851 (2015)
While overexpression of TGFα has been reported in human pancreatic ductal adenocarcinoma (PDAC), mice with overexpressed TGFα develop premalignant pancreatic acinar-to-ductal metaplasia (ADM) but not PDAC. TGF-β signaling pathway is pivotal to the
Externí odkaz:
https://doaj.org/article/f791ae4c2ba44ad49e0d2c3bff6cef35
Autor:
Xuanfu Xu, Bin Su, Chuangao Xie, Shumei Wei, Yingqun Zhou, Hua Liu, Weiqi Dai, Ping Cheng, Fan Wang, Xiaorong Xu, Chuanyong Guo
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e96441 (2014)
The hedgehog signaling pathway plays an important role in EMT of pancreatic cancer cells, but the precise mechanisms remain elusive. Because S100A4 as a key EMT moleculer marker was found to be upregulated upon Gli1 in pancreatic cancer cells, we foc
Externí odkaz:
https://doaj.org/article/a69c0d1656834959818b501b093652f0
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e58637 (2013)
Dysregulated miRNAs play critical roles during carcinogenesis and cancer progression. In the present study, the function of miR-1228* in regulating cancer progression was investigated in gastric cancer. Decreased expression of miR-1228* was observed
Externí odkaz:
https://doaj.org/article/da10f987cbdd4ef4a9f388602731aa54
Autor:
Xuanfu Xu, Yingqun Zhou, Chuangao Xie, Shu-mei Wei, Huizhong Gan, Shengli He, Fan Wang, Ling Xu, Jie Lu, Weiqi Dai, Lei He, Ping Chen, Xingpeng Wang, Chuanyong Guo
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43119 (2012)
The role of sonic hedgehog (SHH) in epithelial mesenchymal transition (EMT) of pancreatic cancer (PC) is known, however, its mechanism is unclear. Because SHH promotes tumor development predominantly through Gli1, we sought to understand its mechanis
Externí odkaz:
https://doaj.org/article/3db0d66cd2964e5a8e8465d943f7866c
Autor:
Xiaorong Xu, Xuan-Fu Xu, Weiqi Dai, Shumei Wei, Hui Zhang, Hua Liu, Shengli He, Chuanyong Guo, Chuangao Xie
Publikováno v:
Pancreas. 44:1252-1258
OBJECTIVES The Hh (hedgehog) signaling pathway is still waiting for further studies because its downstream molecular mechanism remains elusive. Because EIF5A2 (eukaryotic translation initiation factor 5A2) gene was up-regulated upon Gli1 (GLI family
Publikováno v:
Pancreas. 47(6)
Objective The epidermal growth factor receptor is overexpressed in the majority of pancreatic cancer. Epidermal growth factor receptor tyrosine kinase inhibitor erlotinib was approved to treat patients combining with gemcitabine. However, the sensiti
Autor:
Liming Shao, Xuan-Fu Xu, Litao Jia, Jiamin Chen, Jianting Cai, Chuangao Xie, Shumei Wei, Xingpeng Wang
Publikováno v:
Oncology Letters
The purpose of the present study was to elucidate the effects of cyclooxygenase 2 (COX-2) on the expression of vascular endothelial growth factor (VEGF) and prostaglandin E2 (PGE2) in pancreatic cancer in vitro and in vivo, and to clarify the potenti
Publikováno v:
Life sciences. 180
Our previous study has shown that microRNA-1228
Autor:
Nathan Akhavan, Gloria H. Su, Wanglong Qiu, Stuart A. Fine, Chuangao Xie, Naoki Maehara, Dario Garcia-Carracedo, Dillon C. Karg, Chih Chieh Yu, Frank Schönleben, Robert L. Fine, Helen Remotti
Publikováno v:
PLoS ONE
PLoS ONE, Vol 10, Iss 3, p e0120851 (2015)
PLoS ONE, Vol 10, Iss 3, p e0120851 (2015)
Aims While overexpression of TGF alpha has been reported in human pancreatic ductal adenocarcinoma (PDAC), mice with overexpressed TGF alpha develop premalignant pancreatic acinar-to-ductal metaplasia (ADM) but not PDAC. TGF-beta signaling pathway is
Autor:
Bin Su, Weiqi Dai, Xuan-Fu Xu, Yingqun Zhou, Fan Wang, Hua Liu, Ping Cheng, Xiaorong Xu, Chuangao Xie, Shumei Wei, Chuanyong Guo
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e96441 (2014)
PLoS ONE
PLoS ONE
Aims The hedgehog signaling pathway plays an important role in EMT of pancreatic cancer cells, but the precise mechanisms remain elusive. Because S100A4 as a key EMT moleculer marker was found to be upregulated upon Gli1 in pancreatic cancer cells, w