Zobrazeno 1 - 10
of 257
pro vyhledávání: '"Chuanfa Ni"'
Autor:
Dingben Chen, Ling Huang, Mingyu Liang, Xiaojing Chen, Dongdong Cao, Pan Xiao, Chuanfa Ni, Jinbo Hu
Publikováno v:
Molecules, Vol 29, Iss 12, p 2905 (2024)
The direct 1,6-nucleophilic difluoromethylation, trifluoromethylation, and difluoroalkylation of para-quinone methides (p-QMs) with Me3SiRf (Rf = CF2H, CF3, CF2CF3, CF2COOEt, and CF2SPh) under mild conditions are described. Although Me3SiCF2H shows l
Externí odkaz:
https://doaj.org/article/070b5fb724e44b36909f962e7e864f75
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-8 (2022)
Azides are common moieties in chemical synthesis. Here the authors present a methodology to synthesize alkyl azides in one step from simple alcohols under mild conditions.
Externí odkaz:
https://doaj.org/article/893505ed6540425e8bef6a56aebaa614
Publikováno v:
Molecules, Vol 27, Iss 20, p 7076 (2022)
A reagent-controlled highly stereoselective reaction between (S)-difluoromethyl phenyl sulfoximine 1 and imines is reported, and this synthetic method provides a variety of enantiomerically enriched α-difluoromethyl amines. The main pros of this app
Externí odkaz:
https://doaj.org/article/59e3f1ead10e470497c423dfaaa27dce
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
Fluorination of organic molecules can dramatically change the properties and is commonly used for the synthesis of bioactive molecules. Here, the authors report the deoxyfluorination of alcohols and the selective monofluorination of diols using bench
Externí odkaz:
https://doaj.org/article/a543bfff6b39429489f2280db98b4d64
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 10, Iss 1, Pp 344-351 (2014)
Background: 1,1-Difluoroalkenes cannot only be used as valuable precursors for organic synthesis, but also act as bioisosteres for enzyme inhibitors. Among various methods for their preparation, the carbonyl olefination with difluoromethylene phospho
Externí odkaz:
https://doaj.org/article/6634ba7affb24527a054ed8e3049772d
Publikováno v:
CHIMIA, Vol 68, Iss 6 (2014)
Fluorinated compounds are of significant importance in various fields due to their unique chemical, physical, and biological properties. Accordingly, the incorporation of fluorine atom(s) or fluorine-containing functionalities into organic molecules
Externí odkaz:
https://doaj.org/article/a4105dfe01f34b6ea698888e051af42f
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 4, Iss 1, p 21 (2008)
BackgroundAlthough the nucleophilic difluoromethylation of aldehydes, ketones, and imines has been realized with PhSO2CF2H and related reagents, there are still no reports on the enantioselective nucleophilic reactions.ResultsWith a chiral quaternary
Externí odkaz:
https://doaj.org/article/7b7f303622ae457e8c5de9b5baa8dd3a
Publikováno v:
SCIENTIA SINICA Chimica. 53:375-387
Publikováno v:
CCS Chemistry. 4:3648-3659
Publikováno v:
Organic Letters. 24:5982-5987
β-Fluorinated amine is highly desirable for biological and pharmaceutical science, because replacing a C-H bond with a C-F bond can change the physical and chemical properties of the parent molecule to a large extent but not significantly alter its