Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Chuan-xu Liu"'
Autor:
Hu Lei, Han-Zhang Xu, Hui-Zhuang Shan, Meng Liu, Ying Lu, Zhi-Xiao Fang, Jin Jin, Bo Jing, Xin-Hua Xiao, Shen-Meng Gao, Feng-Hou Gao, Li Xia, Li Yang, Li-Gen Liu, Wei-Wei Wang, Chuan-Xu Liu, Yin Tong, Yun-Zhao Wu, Jun-Ke Zheng, Guo-Qiang Chen, Li Zhou, Ying-Li Wu
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Resistance to tyrosine kinase inhibitors (TKI) is a limitation to their use in treating chronic myelogenous leukemia (CML). Here, the authors show that targeting the ubiquitin peptidase USP47 overcomes TKI resistance and eliminates leukaemia stem/pro
Externí odkaz:
https://doaj.org/article/ef7347958ad8427eacd75d192110f022
Autor:
Yang Zhu, Shu Tian, Hua Zhong, Wenhao Zhang, Lifeng Wang, Rong Tao, Zhi-Chao Li, Hao Ding, Lina Jin, Chuanying Zhu, Yu-Jie Ma, Chuan-xu Liu, Siguo Hao, Lan Xu
Publikováno v:
British Journal of Haematology. 196:939-946
Early-stage natural killer/T-cell lymphoma (NK/TCL) patients usually receive a combination of chemotherapy and radiotherapy, but the optimal treatment approach has not yet been established. This study aimed to investigate the efficacy and safety prof
Autor:
Li Yang, Feng-Hou Gao, Guo-Qiang Chen, Hu Lei, Li Xia, Yin Tong, Zhixiao Fang, Xinhua Xiao, Bo Jing, Huizhuang Shan, Ying-Li Wu, Ligen Liu, Junke Zheng, Jin Jin, Li Zhou, Ying Lu, Chuan-Xu Liu, Meng Liu, Shen-Meng Gao, Weiwei Wang, Hanzhang Xu, Yunzhao Wu
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Nature Communications
Nature Communications
Identifying novel drug targets to overcome resistance to tyrosine kinase inhibitors (TKIs) and eradicating leukemia stem/progenitor cells are required for the treatment of chronic myelogenous leukemia (CML). Here, we show that ubiquitin-specific pept
Autor:
Biao Jiang, Ting Luo, Zhang Yongqiang, Youping Zhang, YungTing Chang, Chuan-Xu Liu, Siguo Hao, Xinyu Ding, Qianqian Yin
Publikováno v:
Biochemical and biophysical research communications. 547
Although acute myeloid leukemia (AML) is a highly heterogeneous disease with diverse genetic subsets, one hallmark of AML blasts is myeloid differentiation blockade. Extensive evidence has indicated that differentiation induction therapy represents a
Autor:
Huizhuang Shan, Yanjie Ji, Ying-Li Wu, Jiong Zhang, Zhihui Zou, Huchen Zhou, Chunmin Ma, Meng Liu, Yunzhao Wu, Li Yang, Hanzhang Xu, Ying Zhang, Li Zhou, Ligen Liu, Yang Cao, Hu Lei, Haiyan Cai, Chuan-Xu Liu
Publikováno v:
Chemico-biological interactions. 351
Introduction Despite the rapid progress in the diagnosis and treatment, the prognosis of some types of non-Hodgkin's lymphoma (NHL), especially those with double-hit or double-expressor genotypes, remains poor. Novel targets and compounds are needed
Autor:
Yin Tong, Li Yang, Yugen Zhang, Li Zhou, Bo Jing, Ying-Li Wu, Yu Xia, Haiyan Cai, Meng Hu, Hanzhang Xu, Hao Luo, Hu Lei, Junmei Yang, Chuan-Xu Liu
Publikováno v:
Cancer Cell International
Cancer Cell International, Vol 19, Iss 1, Pp 1-14 (2019)
Cancer Cell International, Vol 19, Iss 1, Pp 1-14 (2019)
Background T-cell acute lymphoblastic leukemia (T-ALL) is a lymphoid malignancy caused by the oncogenic transformation of immature T-cell progenitors with poor outcomes. WP1130 has shown potent activity against a variety of cancer but whether WP1130
Autor:
Yun Yu, Lili Song, Ying-Li Wu, Jian-Xin Pu, Hanzhang Xu, Li Xia, Wei Wei, Han-Dong Sun, Hu Lei, Dongjun Qin, Chuan-Xu Liu, Weiwei Wang, Siguo Hao
Publikováno v:
Molecular Medicine Reports. 13:2201-2207
Although 1,25‑dihydroxyvitamin D3 (VD3) is regarded as a promising inducing agent for leukemia cell differentiation, it is not as effective an agent as all‑trans‑retinoic acid, and its usefulness is also limited by the adverse effects of hyperc
Autor:
Ying-Li Wu, Dongjun Qin, Chunmin Ma, Li Xia, Wei Wei, Zhimin Huang, Feng-Hou Gao, Chuan-Xu Liu, Yun Yu, Jian Zhang, Min Huang, Hu Lei, Yang Cao, Yin Tong, Yingyi Chen, Hanzhang Xu, Tong-Dan Wang, Li Yang
Publikováno v:
Oncotarget
Identifying novel targets to enhance leukemia-cell differentiation is an urgent requirement. We have recently proposed that inhibiting the antioxidant enzyme peroxiredoxin I (Prdx I) may induce leukemia-cell differentiation. However, this concept rem
Publikováno v:
Applied Mechanics and Materials. 709:485-490
Reasonable number of direction finding station is examined in multi-station bearing-crossing location. Though it is believed that increasing the number of station is helpful to improve the location accuracy, In the paper, the maximum likelihood estim
Publikováno v:
Applied Mechanics and Materials. :3096-3099
In this paper, the data mining technology and the mining process was explained; and several common methods of data mining were described. Based on the characteristics of the target value, application of text classification and textual association in