Helicobacter pylori–Induced Rev-erbα Fosters Gastric Bacteria Colonization by Impairing Host Innate and Adaptive Defense

Autor: Rui Xie, Jingyu Xu, Yong-sheng Teng, Chuan-jie Hao, Shi-Ming Yang, Weisan Chen, Tao Liu, Yi-pin Lv, Yuan Zhuang, Quanming Zou, Fang-yuan Mao, Ping Cheng, Yu-gang Liu

Publikováno v: Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 2, Pp 395-425 (2021)
Cellular and Molecular Gastroenterology and Hepatology

Background & Aims Rev-erbα represents a powerful transcriptional repressor involved in immunity. However, the regulation, function, and clinical relevance of Rev-erbα in Helicobacter pylori infection are presently unknown. Methods Rev-erbα was exa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1709675849435bdb7635457d1ff336db
https://doi.org/10.1016/j.jcmgh.2021.02.013

Decreased IL-17RB expression impairs CD11b+CD11c− myeloid cell accumulation in gastric mucosa and host defense during the early-phase of Helicobacter pylori infection

Autor: Yuan Zhuang, Xian-hua Chen, Yong-sheng Teng, Ting-ting Wang, Jia Han, Quanming Zou, Shi-Ming Yang, Jin-yu Zhang, Fang-yuan Mao, Hui Kong, Yu-gang Liu, Chuan-jie Hao, Weisan Chen, Bin Han, Yi-pin Lv, Liu-sheng Peng, Ping Cheng, Qiang Ma

Publikováno v: Cell Death and Disease, Vol 10, Iss 2, Pp 1-14 (2019)

Interleukin-17 receptor B (IL-17RB), a member of the IL-17 receptor family activated by IL-17B/IL-17E, has been shown to be involved in inflammatory diseases. However, the regulation and function of IL-17RB in Helicobacter pylori (H. pylori) infectio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f0c91a15fc76675b665e325277b0c09
http://link.springer.com/article/10.1038/s41419-019-1312-z

Abrogation of cathepsin C by Helicobacter pylori impairs neutrophil activation to promote gastric infection

Autor: Xiao-long Wu, Yong Sheng Teng, Ting-ting Wang, Yang Sm, Liu Sheng Peng, Yuan Zhuang, Jin Yu Zhang, Weisan Chen, Ping Cheng, Bin Han, Yi Pin Lv, Hui Kong, Chuan Jie Hao, Quan Ming Zou, Qiang Ma, Fang Yuan Mao, Yu-gang Liu

Publikováno v: The FASEB Journal. 33:5018-5033

Cathepsin C (CtsC) functions as a central coordinator for activation of many serine proteases in immune cells. However, CtsC expression in gastric epithelial cells and its role in Helicobacter pylori infection remain unclear. Real-time PCR, Western b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::900f3d82ca65bfc489c2e9ab20ccaf7a
https://doi.org/10.1096/fj.201802016rr

Increased intratumoral mast cells foster immune suppression and gastric cancer progression through TNF-α-PD-L1 pathway

Autor: Yu-gang Liu, Yong-liang Zhao, Fang-yuan Mao, Jin-yu Zhang, Na Chen, Bin Han, Chuan-jie Hao, Jun Chen, Yi-pin Lv, Xianhua Wang, Yong-sheng Teng, Liu-sheng Peng, Hui Kong, Weisan Chen, Qiang Ma, Ping Cheng, Yuan Zhuang, Ting-ting Wang, Quanming Zou

Publikováno v: Journal for Immunotherapy of Cancer
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-15 (2019)

Background Mast cells are prominent components of solid tumors and exhibit distinct phenotypes in different tumor microenvironments. However, the nature, regulation, function, and clinical relevance of mast cells in human gastric cancer (GC) are pres

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fb698fcc0fa2745246227b6604275ca
http://europepmc.org/articles/PMC6390584

Decreased IL-17RB expression impairs CD11b

Autor: Yong-Sheng, Teng, Yu-Gang, Liu, Xian-Hua, Chen, Ting-Ting, Wang, Ping, Cheng, Yi-Pin, Lv, Hui, Kong, Fang-Yuan, Mao, Chuan-Jie, Hao, Shi-Ming, Yang, Weisan, Chen, Jin-Yu, Zhang, Liu-Sheng, Peng, Bin, Han, Qiang, Ma, Jia, Han, Quan-Ming, Zou, Yuan, Zhuang

Publikováno v: Cell Death & Disease

Interleukin-17 receptor B (IL-17RB), a member of the IL-17 receptor family activated by IL-17B/IL-17E, has been shown to be involved in inflammatory diseases. However, the regulation and function of IL-17RB in Helicobacter pylori (H. pylori) infectio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8fe8a4b12a1325e1709c703804ad088c
https://pubmed.ncbi.nlm.nih.gov/30692510