Zobrazeno 1 - 10
of 1 899
pro vyhledávání: '"Chuan Qin"'
Autor:
Yue Tang, Ming-Hao Dong, Xiao-Wei Pang, Hang Zhang, Yun-Hui Chu, Luo-Qi Zhou, Sheng Yang, Lu-Yang Zhang, Yun-Fan You, Li-Fang Zhu, Wei Wang, Chuan Qin, Dai-Shi Tian
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-17 (2024)
Abstract Circulating miR-30c-2-3p has been closely related to vascular diseases, however, its role and underlying mechanisms in ischemic stroke remained unclear. Our study addressed this gap by observing elevated levels of exosomal miR-30c-2-3p in pa
Externí odkaz:
https://doaj.org/article/1ef79620e5954a4292516fb148491c7b
Autor:
Leonie G. Graf, Carlos Moreno-Yruela, Chuan Qin, Sabrina Schulze, Gottfried J. Palm, Ole Schmöker, Nancy Wang, Dianna M. Hocking, Leila Jebeli, Britta Girbardt, Leona Berndt, Babett Dörre, Daniel M. Weis, Markus Janetzky, Dirk Albrecht, Daniela Zühlke, Susanne Sievers, Richard A. Strugnell, Christian A. Olsen, Kay Hofmann, Michael Lammers
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-31 (2024)
Abstract Classical Zn2+-dependent deac(et)ylases play fundamental regulatory roles in life and are well characterized in eukaryotes regarding their structures, substrates and physiological roles. In bacteria, however, classical deacylases are less we
Externí odkaz:
https://doaj.org/article/ccf2c27a6704404393014ebb3e735864
Autor:
Min Liu, Jirong Pan, Xiaomeng Li, Xueling Zhang, Fan Tian, Mingfeng Li, Xinghan Wu, Ling Zhang, Chuan Qin
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-21 (2024)
Abstract Background The Interleukin-6 (IL-6)-signal transducer and activator of transcription 3 (STAT3) pathway, along with the cyclic GMP-AMP synthase (cGAS)-stimulator of interferon genes (STING) pathway, are critical contributors to neuroinflammat
Externí odkaz:
https://doaj.org/article/fe78d0f2ba754738b7507cb2695b4015
Autor:
Boyi Cong, Xuan Dong, Zongheng Yang, Pin Yu, Yangyang Chai, Jiaqi Liu, Meihan Zhang, Yupeng Zang, Jingmin Kang, Yu Feng, Yi Liu, Weimin Feng, Dehe Wang, Wei Deng, Fengdi Li, Zhiqi Song, Ziqiao Wang, Xiaosu Chen, Hua Qin, Qinyi Yu, Zhiqing Li, Shuxun Liu, Xun Xu, Nanshan Zhong, Xianwen Ren, Chuan Qin, Longqi Liu, Jian Wang, Xuetao Cao
Publikováno v:
Cell Discovery, Vol 10, Iss 1, Pp 1-13 (2024)
Abstract How the lung achieves immune homeostasis after a pulmonary infection is not fully understood. Here, we analyzed the spatiotemporal changes in the lungs over a 2-week natural recovery from severe pneumonia in a Syrian hamster model of SARS-Co
Externí odkaz:
https://doaj.org/article/733967fd5aa649879b1739b6ee8d6284
Autor:
Boyi Cong, Xuan Dong, Zongheng Yang, Pin Yu, Yangyang Chai, Jiaqi Liu, Meihan Zhang, Yupeng Zang, Jingmin Kang, Yu Feng, Yi Liu, Weimin Feng, Dehe Wang, Wei Deng, Fengdi Li, Zhiqi Song, Ziqiao Wang, Xiaosu Chen, Hua Qin, Qinyi Yu, Zhiqing Li, Shuxun Liu, Xun Xu, Nanshan Zhong, Xianwen Ren, Chuan Qin, Longqi Liu, Jian Wang, Xuetao Cao
Publikováno v:
Cell Discovery, Vol 10, Iss 1, Pp 1-12 (2024)
Abstract How immune cells are spatiotemporally coordinated in the lung to effectively monitor, respond to, and resolve infection and inflammation in primed form needs to be fully illustrated. Here we apply immunocartography, a high-resolution techniq
Externí odkaz:
https://doaj.org/article/015bcc60a9774d3ca16d3606646e4482
Autor:
Lu-Lu Xu, Sheng Yang, Luo-Qi Zhou, Yun-Hui Chu, Xiao-Wei Pang, Yun-Fan You, Hang Zhang, Lu-Yang Zhang, Li-Fang Zhu, Lian Chen, Ke Shang, Jun Xiao, Wei Wang, Dai-Shi Tian, Chuan Qin
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-15 (2024)
Abstract Chronic cerebral hypoperfusion (CCH), a disease afflicting numerous individuals worldwide, is a primary cause of cognitive deficits, the pathogenesis of which remains poorly understood. Bruton’s tyrosine kinase inhibition (BTKi) is conside
Externí odkaz:
https://doaj.org/article/116ae8d96fbb4adba3e3cbc90badd584
Autor:
Jianjun Wang, Han Li, Junchao Hu, Ruizi Shi, Chuan Qin, Xi Chen, Sirui Chen, Xintao Zeng, Hua Luo, Huiwen Luo, Yulong Zhou, Pei Yang, Decai Wang
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract The triglyceride-glucose (TyG) index is a novel marker of insulin resistance that has been strongly associated with many diseases related to metabolic disorders, such as diabetes, coronary heart disease, myocardial infarction, obesity, nonal
Externí odkaz:
https://doaj.org/article/1b6e536aeff44db4a55b1f6055913682
Autor:
Chuan Qin, Leonie G. Graf, Kilian Striska, Markus Janetzky, Norman Geist, Robin Specht, Sabrina Schulze, Gottfried J. Palm, Britta Girbardt, Babett Dörre, Leona Berndt, Stefan Kemnitz, Mark Doerr, Uwe T. Bornscheuer, Mihaela Delcea, Michael Lammers
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-22 (2024)
Abstract The AMP-forming acetyl-CoA synthetase is regulated by lysine acetylation both in bacteria and eukaryotes. However, the underlying mechanism is poorly understood. The Bacillus subtilis acetyltransferase AcuA and the AMP-forming acetyl-CoA syn
Externí odkaz:
https://doaj.org/article/dc277252131d4568afb2aac51547d6c8
Publikováno v:
Animal Models and Experimental Medicine, Vol 7, Iss 3, Pp 347-361 (2024)
Abstract Background Apolipoprotein E4 (ApoE4) allele is the strongest genetic risk factor for late‐onset Alzheimer's disease, and it can aggravate depressive symptoms in non‐AD patients. However, the impact of ApoE4 on AD‐associated depression
Externí odkaz:
https://doaj.org/article/aafee32291554212bbe8b373ecb6376c
Autor:
Jianjun Wang, Sirui Chen, Xi Chen, Chuan Qin, Junchao Hu, Xintao Zeng, Hua Luo, Pei Yang, Huiwen Luo, Chuanpeng Yuan, Ruizi Shi, Decai Wang
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
BackgroundThe aim of this study is to evaluate the association between triglyceride glucose-waist height ratio (TyG-WHtR) index and the prevalence of gallstone disease (GSD), alongside the age at first gallstone surgery among adult populations within
Externí odkaz:
https://doaj.org/article/78531d63caf2423e8251d528d1bb7f9d