Zobrazeno 1 - 10
of 1 890
pro vyhledávání: '"Chuan QIN"'
Autor:
Lu-Lu Xu, Sheng Yang, Luo-Qi Zhou, Yun-Hui Chu, Xiao-Wei Pang, Yun-Fan You, Hang Zhang, Lu-Yang Zhang, Li-Fang Zhu, Lian Chen, Ke Shang, Jun Xiao, Wei Wang, Dai-Shi Tian, Chuan Qin
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-15 (2024)
Abstract Chronic cerebral hypoperfusion (CCH), a disease afflicting numerous individuals worldwide, is a primary cause of cognitive deficits, the pathogenesis of which remains poorly understood. Bruton’s tyrosine kinase inhibition (BTKi) is conside
Externí odkaz:
https://doaj.org/article/116ae8d96fbb4adba3e3cbc90badd584
Autor:
Jianjun Wang, Han Li, Junchao Hu, Ruizi Shi, Chuan Qin, Xi Chen, Sirui Chen, Xintao Zeng, Hua Luo, Huiwen Luo, Yulong Zhou, Pei Yang, Decai Wang
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract The triglyceride-glucose (TyG) index is a novel marker of insulin resistance that has been strongly associated with many diseases related to metabolic disorders, such as diabetes, coronary heart disease, myocardial infarction, obesity, nonal
Externí odkaz:
https://doaj.org/article/1b6e536aeff44db4a55b1f6055913682
Autor:
Chuan Qin, Leonie G. Graf, Kilian Striska, Markus Janetzky, Norman Geist, Robin Specht, Sabrina Schulze, Gottfried J. Palm, Britta Girbardt, Babett Dörre, Leona Berndt, Stefan Kemnitz, Mark Doerr, Uwe T. Bornscheuer, Mihaela Delcea, Michael Lammers
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-22 (2024)
Abstract The AMP-forming acetyl-CoA synthetase is regulated by lysine acetylation both in bacteria and eukaryotes. However, the underlying mechanism is poorly understood. The Bacillus subtilis acetyltransferase AcuA and the AMP-forming acetyl-CoA syn
Externí odkaz:
https://doaj.org/article/dc277252131d4568afb2aac51547d6c8
Publikováno v:
Animal Models and Experimental Medicine, Vol 7, Iss 3, Pp 347-361 (2024)
Abstract Background Apolipoprotein E4 (ApoE4) allele is the strongest genetic risk factor for late‐onset Alzheimer's disease, and it can aggravate depressive symptoms in non‐AD patients. However, the impact of ApoE4 on AD‐associated depression
Externí odkaz:
https://doaj.org/article/aafee32291554212bbe8b373ecb6376c
Autor:
Yuxin Liu, Minghao Dong, Yunhui Chu, Luoqi Zhou, Yunfan You, Xiaowei Pang, Sheng Yang, Luyang Zhang, Lian Chen, Lifang Zhu, Jun Xiao, Wei Wang, Chuan Qin, Daishi Tian, Ting Gao
Publikováno v:
Chinese Medical Journal, Vol 137, Iss 10, Pp 1140-1150 (2024)
Abstract. Chimeric antigen receptor (CAR)-T cell therapy has achieved remarkable success in the treatment of hematological malignancies. Based on the immunomodulatory capability of CAR-T cells, efforts have turned toward exploring their potential in
Externí odkaz:
https://doaj.org/article/e3e571adddf0477cafcd608c82ec9be6
Autor:
Wei Deng, Linlin Bao, Zhiqi Song, Ling Zhang, Pin Yu, Yanfeng Xu, Jue Wang, Wenjie Zhao, Xiuqin Zhang, Yunlin Han, Yanhong Li, Jiangning Liu, Qi Lv, Xujian Liang, Fengdi Li, Feifei Qi, Ran Deng, Siyuan Wang, Yibai Xiong, Ruiping Xiao, Hongyang Wang, Chuan Qin
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-18 (2024)
Abstract Evidence suggests associations between COVID-19 patients or vaccines and glycometabolic dysfunction and an even higher risk of the occurrence of diabetes. Herein, we retrospectively analyzed pancreatic lesions in autopsy tissues from 67 SARS
Externí odkaz:
https://doaj.org/article/2244ca96f4904928b835e640c27826a0
Autor:
Ruizi Shi, Pei Yang, Yangjie Guo, Yiping Tang, Hua Luo, Chuan Qin, Ting Jiang, Yu Huang, Ziqing Gao, Xintao Zeng, Jianjun Wang
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
BackgroundBenign tumors of the spleen are rare compared to those of other parenchymal organs, accounting for less than 0.007% of all tumors, and are often found incidentally. Splenolymphangiomas are much rarer, commonly occur in children, and tend to
Externí odkaz:
https://doaj.org/article/cf35debee98d4200b43f600061cd2f05
Autor:
Dai-Shi Tian, Chuan Qin, Ming-Hao Dong, Michael Heming, Luo-Qi Zhou, Wen Wang, Song-Bai Cai, Yun-Fan You, Ke Shang, Jun Xiao, Di Wang, Chun-Rui Li, Min Zhang, Bi-Tao Bu, Gerd Meyer zu Hörste, Wei Wang
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 4, Pp 966-987 (2024)
Abstract B-cell maturation antigen (BCMA), expressed in plasmablasts and plasma cells, could serve as a promising therapeutic target for autoimmune diseases. We reported here chimeric antigen receptor (CAR) T cells targeting BCMA in two patients with
Externí odkaz:
https://doaj.org/article/bbc6bbd3f3864e94abcc50e72aa7cf93
Autor:
Tse-Chun Chen, Meghana Ramesh, Chuan Qin, Bharat Vyakaranam, Zhangshuan Hou, Travis C. Douville, Nader A. Samaan
Publikováno v:
IEEE Access, Vol 12, Pp 115319-115328 (2024)
The increasing penetration of renewable energy sources and energy storage in the power grid has led to an exponentially large number of possible power generation scenarios. This makes it difficult to analyze, plan, and operate the power system, and n
Externí odkaz:
https://doaj.org/article/dc17ba43e0424eeb981e9fa64af69b16
Autor:
Xinxing Wang, Wei Su, Chuan Qin, Ruxin Gao, Shuai Shao, Xianwen Xu, Zhenhai Zhang, Junlin Gao
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 29, Iss 7, p 269 (2024)
Background: The TGF-β gene is a gemcitabine (GEM) resistance gene; however, the mechanism by which it regulates GEM resistance in pancreatic cancer remains unclear. Methods: The PANC-1 cell line was treated with GEM and then stimulated with TGF-β.
Externí odkaz:
https://doaj.org/article/e0a7d2a44e484fdf9d8c9e0bc10a6c85