Zobrazeno 1 - 10
of 1 245
pro vyhledávání: '"Chuan, Xu"'
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors (TKIs) are the most applied targeted therapy for EGFR-mutant lung adenocarcinoma (LUAD). The third-generation EGFR-TKI, osimertinib, is widely used throughout lung cancer tre
Externí odkaz:
https://doaj.org/article/39ee13eba0734f14901c11e5583b3e95
Autor:
Hao Geng, Dongdong Tang, Kuokuo Li, Chuan Xu, Chao Wang, Xiansheng Zhang, Xiaojin He, Yunxia Cao
Publikováno v:
BMC Medical Genomics, Vol 17, Iss 1, Pp 1-8 (2024)
Abstract Background Androgen insensitivity syndrome (AIS) is a rare genetic disorder characterized by resistance to androgens, mainly due to mutations in the androgen receptor (AR) gene. It can manifest as complete AIS, partial AIS and mild AIS. Whil
Externí odkaz:
https://doaj.org/article/30961503f16841548db1f507c01b820a
Publikováno v:
BMC Gastroenterology, Vol 24, Iss 1, Pp 1-20 (2024)
Abstract Background Positive regulators of T-cell function (PTFRs), integral to T-cell proliferation and activation, have been identified as potential prognostic markers in colorectal cancer (CRC). Despite this, their role within the tumor microenvir
Externí odkaz:
https://doaj.org/article/0cfad842140c46f0bcfa3d534a77cae3
Autor:
Senzhao Guo, Dongdong Tang, Yuge Chen, Hui Yu, Meng Gu, Hao Geng, Jiajun Fang, Baoyan Wu, Lewen Ruan, Kuokuo Li, Chuan Xu, Yang Gao, Qing Tan, Zongliu Duan, Huan Wu, Rong Hua, Rui Guo, Zhaolian Wei, Ping Zhou, Yuping Xu, Yunxia Cao, Xiaojin He, Yanwei Sha, Mingrong Lv
Publikováno v:
Human Genomics, Vol 18, Iss 1, Pp 1-14 (2024)
Abstract Background Bi-allelic variants in DNAH11 have been identified as causative factors in Primary Ciliary Dyskinesia, leading to abnormal respiratory cilia. Nonetheless, the specific impact of these variants on human sperm flagellar and their in
Externí odkaz:
https://doaj.org/article/bcae212b4dd14b8780586dfa1438e051
Autor:
Baoyan Wu, Yuying Sheng, Wenwei Yu, Lewen Ruan, Hao Geng, Chuan Xu, Chao Wang, Dongdong Tang, Mingrong Lv, Rong Hua, Kuokuo Li
Publikováno v:
BMC Molecular and Cell Biology, Vol 25, Iss 1, Pp 1-9 (2024)
Abstract Background Hepatitis B virus (HBV) infection poses a substantial threat to human health, impacting not only infected individuals but also potentially exerting adverse effects on the health of their offspring. The underlying mechanisms drivin
Externí odkaz:
https://doaj.org/article/9d1bed3438174b83aab16b47030d2a94
Autor:
Chengjian He, Chuan Xu, Chen Chen, Jinmeng Tong, Tianya Zhou, Su Sun, Zhibo Liu, Hui-Ming Cheng, Wencai Ren
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract Two-dimensional semiconductors with high thermal conductivity and charge carrier mobility are of great importance for next-generation electronic and optoelectronic devices. However, constrained by the long-held Slack’s criteria, the report
Externí odkaz:
https://doaj.org/article/1e185394c1354d56aaaf299627f8c552
Autor:
Hong Wu, Qianshi Liu, Jingpei Li, Xuefeng Leng, Yazhou He, Yiqiang Liu, Xia Zhang, Yujie Ouyang, Yang Liu, Wenhua Liang, Chuan Xu
Publikováno v:
Advanced Science, Vol 11, Iss 41, Pp n/a-n/a (2024)
Abstract Few predictive biomarkers exist for identifying patients who may benefit from neoadjuvant therapy (NAT). The intratumoral microbial composition is comprehensively profiled to predict the efficacy and prognosis of patients with esophageal squ
Externí odkaz:
https://doaj.org/article/731ef54934284541ad249f7176df2a27
Publikováno v:
STAR Protocols, Vol 5, Iss 3, Pp 103267- (2024)
Summary: Bacillus Calmette-Guérin (BCG), the only licensed tuberculosis vaccine, provides non-specific protection against non-tuberculosis diseases that is mediated by trained immunity, a functional reprogramming mediated by innate immune memory. He
Externí odkaz:
https://doaj.org/article/8700c60ebeb54c249d0da943d433eefe
Publikováno v:
Nuclear Materials and Energy, Vol 40, Iss , Pp 101703- (2024)
This paper presents a dynamic analysis tool for evaluating the tritium inventory, tritium extraction and tritium losses for the Water Cooled Ceramic Breeder (WCCB) blanket system of Chinese Fusion Engineering Test Reactor (CFETR). We have developed a
Externí odkaz:
https://doaj.org/article/67454b69a95e43a384beb14626474fa7
Publikováno v:
Cancer Biology & Medicine, Vol 21, Iss 5, Pp 382-399 (2024)
Immune checkpoint inhibitors (ICIs) are used to relieve and refuel anti-tumor immunity by blocking the interaction, transcription, and translation of co-inhibitory immune checkpoints or degrading co-inhibitory immune checkpoints. Thousands of small m
Externí odkaz:
https://doaj.org/article/aa781a13d9664f5395153c422423ff77