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A gel-like condensation of Cidec generates lipid-permeable plates for lipid droplet fusion.

Autor: Lyu X; State Key Laboratory of Membrane Biology and Tsinghua-Peking Center for Life Sciences, Beijing Advanced Innovation Center for Structural Biology, School of Life Sciences, Tsinghua University, Beijing 100084, China., Wang J; State Key Laboratory of Membrane Biology and Tsinghua-Peking Center for Life Sciences, Beijing Advanced Innovation Center for Structural Biology, School of Life Sciences, Tsinghua University, Beijing 100084, China., Wang J; State Key Laboratory of Membrane Biology and Tsinghua-Peking Center for Life Sciences, Beijing Advanced Innovation Center for Structural Biology, School of Life Sciences, Tsinghua University, Beijing 100084, China., Yin YS; Shanghai Key Laboratory of Metabolic Remodeling and Health, Institute of Metabolism and Integrative Biology, Department of Endocrinology and Metabolism, Zhongshan Hospital, Fudan University, Shanghai 200032, China., Zhu Y; Biodynamic Optical Imaging Center (BIOPIC), School of Life Sciences, Peking University, Beijing 100871, China., Li LL; State Key Laboratory of Biomembrane and Membrane Biotechnology, College of Life Sciences, Peking University, Beijing 100871, China., Huang S; Departments of Biological Sciences and Chemistry and NUS Centre for Bio-Imaging Sciences, National University of Singapore, 14 Science Drive 4, Singapore 117557, Singapore., Peng S; Institute of Mechanics, Chinese Academy of Sciences, No.15 Beisihuanxi Road, Beijing 100190, China., Xue B; Biodynamic Optical Imaging Center (BIOPIC), School of Life Sciences, Peking University, Beijing 100871, China., Liao R; State Key Laboratory of Membrane Biology and Tsinghua-Peking Center for Life Sciences, Beijing Advanced Innovation Center for Structural Biology, School of Life Sciences, Tsinghua University, Beijing 100084, China., Wang SQ; State Key Laboratory of Biomembrane and Membrane Biotechnology, College of Life Sciences, Peking University, Beijing 100871, China., Long M; Institute of Mechanics, Chinese Academy of Sciences, No.15 Beisihuanxi Road, Beijing 100190, China., Wohland T; Departments of Biological Sciences and Chemistry and NUS Centre for Bio-Imaging Sciences, National University of Singapore, 14 Science Drive 4, Singapore 117557, Singapore., Chua BT; Shanghai Key Laboratory of Metabolic Remodeling and Health, Institute of Metabolism and Integrative Biology, Department of Endocrinology and Metabolism, Zhongshan Hospital, Fudan University, Shanghai 200032, China., Sun Y; Biodynamic Optical Imaging Center (BIOPIC), School of Life Sciences, Peking University, Beijing 100871, China., Li P; Beijing Advanced Innovation Center for Structural Biology, Tsinghua-Peking Joint Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing 100084, China., Chen XW; State Key Laboratory of Membrane Biology, Center for Life Sciences and Institute of Molecular Medicine, College of Future Technology, Peking University, Beijing 100101, China., Xu L; State Key Laboratory of Membrane Biology and Tsinghua-Peking Center for Life Sciences, Beijing Advanced Innovation Center for Structural Biology, School of Life Sciences, Tsinghua University, Beijing 100084, China; Shanghai Qi Zhi Institute, Shanghai 200030, China., Chen FJ; Shanghai Key Laboratory of Metabolic Remodeling and Health, Institute of Metabolism and Integrative Biology, Department of Endocrinology and Metabolism, Zhongshan Hospital, Fudan University, Shanghai 200032, China; Shanghai Qi Zhi Institute, Shanghai 200030, China. Electronic address: derrick_chen@fudan.edu.cn., Li P; State Key Laboratory of Membrane Biology and Tsinghua-Peking Center for Life Sciences, Beijing Advanced Innovation Center for Structural Biology, School of Life Sciences, Tsinghua University, Beijing 100084, China; Shanghai Qi Zhi Institute, Shanghai 200030, China. Electronic address: li-peng@tsinghua.edu.cn.

Publikováno v: Developmental cell [Dev Cell] 2021 Sep 27; Vol. 56 (18), pp. 2592-2606.e7. Date of Electronic Publication: 2021 Sep 10.

DFCP1 associates with lipid droplets.

Autor: Gao G; State Key Laboratory of Membrane Biology and Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, 100084, Beijing, China., Sheng Y; State Key Laboratory of Membrane Biology and Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, 100084, Beijing, China., Yang H; School of Biotechnology and Biomolecular Sciences, University of New South Wales, 2052 New South Wales, Sydney, Australia., Chua BT; The Institute of Metabolism and Integrative Biology, Fudan University, 200438, Shanghai, China., Xu L; State Key Laboratory of Membrane Biology and Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, 100084, Beijing, China.

Publikováno v: Cell biology international [Cell Biol Int] 2019 Dec; Vol. 43 (12), pp. 1492-1504. Date of Electronic Publication: 2019 Jul 23.

Identification of gene products that control lipid droplet size in yeast using a high-throughput quantitative image analysis.

Autor: Lv X; State Key Laboratory of Membrane Biology and Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing 100084, China., Liu J; State Key Laboratory of Membrane Biology and Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing 100084, China., Qin Y; MOE Key Laboratory of Bioinformatics and Centre for Synthetic and Systems Biology, School of Life Sciences, Tsinghua University, Beijing 100084, China., Liu Y; State Key Laboratory of Membrane Biology and Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing 100084, China., Jin M; State Key Laboratory of Membrane Biology and Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing 100084, China., Dai J; MOE Key Laboratory of Bioinformatics and Centre for Synthetic and Systems Biology, School of Life Sciences, Tsinghua University, Beijing 100084, China., Chua BT; Institute of Metabolism and Integrative Biology, Fudan University, Shanghai 200438, China., Yang H; School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, NSW 2052, Australia., Li P; State Key Laboratory of Membrane Biology and Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing 100084, China. Electronic address: li-peng@mail.tsinghua.edu.cn.

Publikováno v: Biochimica et biophysica acta. Molecular and cell biology of lipids [Biochim Biophys Acta Mol Cell Biol Lipids] 2019 Feb; Vol. 1864 (2), pp. 113-127. Date of Electronic Publication: 2018 Nov 07.

Autophagy Governs Protumorigenic Effects of Mitotic Slippage-induced Senescence.

Autor: Jakhar R; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore., Luijten MNH; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore., Wong AXF; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore., Cheng B; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore., Guo K; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore., Neo SP; Quantitative Proteomics Group, Institute of Molecular and Cell Biology, Agency for Science, Technology, and Research, Singapore., Au B; Translational Immunology Group, Institute of Molecular and Cell Biology, Agency for Science, Technology, and Research, Singapore., Kulkarni M; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore., Lim KJ; Acenzia Inc, Windsor, Ontario, Canada., Maimaiti J; Acenzia Inc, Windsor, Ontario, Canada., Chong HC; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore., Lim EH; Division of Medical Oncology, National Cancer Centre Singapore, Singapore., Tan TBK; Division of Surgical Oncology, National Cancer Centre Singapore, Singapore., Ong KW; Division of Surgical Oncology, National Cancer Centre Singapore, Singapore., Sim Y; Division of Surgical Oncology, National Cancer Centre Singapore, Singapore., Wong JSL; Division of Oncologic Imaging, National Cancer Centre Singapore, Singapore., Khoo JBK; Division of Oncologic Imaging, National Cancer Centre Singapore, Singapore., Ho JTS; Division of Oncologic Imaging, National Cancer Centre Singapore, Singapore., Chua BT; Singapore Oncogenome Program, Institute of Molecular and Cell Biology, Agency for Science, Technology, and Research, Singapore., Sinha I; Acenzia Inc, Windsor, Ontario, Canada., Wang X; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore.; Vascular Biology Group, Institute of Molecular and Cell Biology, Agency for Science, Technology, and Research, Singapore., Connolly JE; Translational Immunology Group, Institute of Molecular and Cell Biology, Agency for Science, Technology, and Research, Singapore.; Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.; Institute of Biomedical Studies, Baylor University, Waco, Texas., Gunaratne J; Quantitative Proteomics Group, Institute of Molecular and Cell Biology, Agency for Science, Technology, and Research, Singapore.; Department of Anatomy, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Crasta KC; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore. kccrasta@ntu.edu.sg.; School of Biological Sciences, Nanyang Technological University, Singapore.; Genomic Instability and Cancer Group, Institute of Molecular and Cell Biology, Agency for Science, Technology, and Research, Singapore.; Department of Medicine, Imperial College London, London, United Kingdom.

Publikováno v: Molecular cancer research : MCR [Mol Cancer Res] 2018 Nov; Vol. 16 (11), pp. 1625-1640. Date of Electronic Publication: 2018 Jul 23.