Zobrazeno 1 - 10
of 115
pro vyhledávání: '"Chu-Young Kim"'
Autor:
Qian Wang, Ning Liu, Yaming Deng, Yuze Guan, Hongli Xiao, Tara A. Nitka, Hui Yang, Anju Yadav, Lela Vukovic, Irimpan I. Mathews, Xi Chen, Chu-Young Kim
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Monensin A is a prototypical natural polyether polyketide antibiotic. It acts by binding a metal cation and facilitating its transport across the cell membrane. Biosynthesis of monensin A involves construction of a polyene polyketide backbon
Externí odkaz:
https://doaj.org/article/c3d2aacc4edf464c8b159b1038c6a154
Autor:
Priyanka Gade, Amanda Erlandson, Anwar Ullah, Xi Chen, Irimpan I. Mathews, Paola E. Mera, Chu-Young Kim
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Echinomycin is a natural product DNA bisintercalator antibiotic. The echinomycin biosynthetic gene cluster in Streptomyces lasalocidi includes a gene encoding the self-resistance protein Ecm16. Here, we present the 2.0 Å resolution crystal
Externí odkaz:
https://doaj.org/article/1809cae47a634d0b9c086c4f7c3184e5
Autor:
Bagde, Saket R., Chu-Young Kim
Publikováno v:
Natural Product Reports; Aug2024, Vol. 41 Issue 8, p1219-1234, 16p
Publikováno v:
Molecular microbiology. 117(6)
Bacteria use various strategies to become antibiotic resistant. The molecular details of these strategies are not fully understood. We can increase our understanding by investigating the same strategies found in antibiotic-producing bacteria. In this
II.SummaryBacteria use various strategies to become antibiotic resistant. The molecular details of these strategies are not fully understood. We can increase our understanding by investigating the same strategies found in antibiotic-producing bacteri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e23b2b250b5a1af11a3b695e32f9e64
https://doi.org/10.1101/2022.02.02.478902
https://doi.org/10.1101/2022.02.02.478902
Autor:
Xiaokang Li, Chu-Young Kim, Huiling Lin, Jian Li, Xi Chen, Bei Jiang, Chunquan Sheng, Ze-Lan Hu, Donglei Shi, Xinming Li, Yuan Guo, Guoqiang Dong, Jinwen Li, Ying Gao, Wenjing Qiu, Yulu Hu, Conglong Xia
Publikováno v:
Chemical Science
Human senescence-associated β-galactosidase (SA-β-gal), the most widely used biomarker of aging, is a valuable tool for assessing the extent of cell ‘healthy aging’ and potentially predicting the health life span of an individual. Human SA-β-g
Publikováno v:
Science
Type I modular polyketide synthases are homodimeric multidomain assembly line enzymes that synthesize a variety of polyketide natural products by performing polyketide chain extension and β-keto group modification reactions. We determined the 2.4-an
Autor:
Yuan Guo, Yulu Hu, Xiaokang Li, Tony D. James, Qimeng Liu, Jian Li, Xi Chen, Chu-Young Kim, Xinming Li, Ying Gao
Publikováno v:
Guo, Y, Gao, Y, Hu, Y, Liu, Q, Li, X, Li, X, Kim, C-Y, James, T D, Li, J & Chen, X 2021, ' Two-Dimensional Design Strategy to Construct Smart Fluorescent Probes for the Precise Tracking of Senescence ', Angewandte Chemie, vol. 133, no. 19, pp. 10851-10860 . https://doi.org/10.1002/ange.202101278
The tracking of cellular senescence usually depends on the detection of senescence‐associated β‐galactosidase (SA‐β‐gal). Previous probes for SA‐β‐gal with this purpose only cover a single dimension: the accumulation of this enzyme in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25d1aa4b22cb9e8f0609e7dfe9aefeba
https://purehost.bath.ac.uk/ws/files/218719773/manuscript_ACIE_26022021.pdf
https://purehost.bath.ac.uk/ws/files/218719773/manuscript_ACIE_26022021.pdf
Publikováno v:
ACS Chemical Biology. 13:3072-3077
During polyketide and fatty acid biosynthesis, the growing acyl chain is attached to the acyl carrier protein via a thioester linkage. The acyl carrier protein interacts with other enzymes that perform chain elongation and chain modification on the b
Publikováno v:
Journal of Propulsion and Power. 34:730-738
This paper reports exhaust measurements performed using a nonintrusive acoustic technique on a JT15D-1A turbofan research engine. Using multiple streamwise displaced microphones, the integrated exh...