Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Chu Yan Chan"'
Autor:
Dan Xie, Fang Ping Xu, Yanhui Liu, Wing Yin Li, Hsiang-Fu Kung, Yangchao Chen, Joseph J.Y. Sung, Hong Yao, Chi Man Cheung, Chu Yan Chan, Ching Yu Chan
Publikováno v:
Cancer Letters. 297:109-116
The function of EZH2 in tumorigenesis and liver metastasis of pancreatic cancer has never been elucidated in vivo. EZH2 was overexpressed in pancreatic carcinomas and its overexpression was associated with tumor differentiation and pT status. Suppres
Autor:
Chun-ling Meng, Ping-Chung Leung, Ming-Liang He, Chu-yan Chan, Jin-fang Zhang, Marie Chia-mi Lin, Yangchao Chen, Hsiang-Fu Kung, Guo Li
Publikováno v:
Molecular and Cellular Endocrinology. 314:70-74
Herba Epimedii is one of the most commonly used Chinese herbs for treating osteoporosis. In the present study, the flavonoids of Herba Epimedii (HEF) have shown to promote the osteogenic differentiation of human bone marrow-derived mesenchymal stem c
Autor:
Qing-Yu He, Yangchao Chen, Ka Fai To, Sai-Ming Ngai, Ming-Liang He, Minnie Y.Y. Go, Hua Wang, Sau-na Tsai, Joanna H.M. Tong, Henry Lik-Yuen Chan, Yan Ma, Chu-yan Chan, Hsiang-Fu Kung, Jun Yu, Christopher H.K. Cheng, Joseph J.Y. Sung, Ying Chen
Publikováno v:
Molecular & Cellular Proteomics
Hepatitis B virus (HBV) infection is a global public health problem that plays a crucial role in the pathogenesis of chronic hepatitis, cirrhosis, and hepatocellular carcinoma. However, the pathogenesis of HBV infection and the mechanisms of host-vir
Autor:
Shao-Chun Chen, Hua Wang, Hsiang-Fu Kung, Zhongtang Feng, Yangchao Chen, David T. Yew, Gang Lu, Chu-yan Chan
Publikováno v:
Journal of Molecular Neuroscience. 41:12-16
This study examined the protein expression profile changes in the brain of senescence-accelerated mice/prone 8 (SAMP8) model. Two approaches, namely microarray and RT-PCR, were used in the study. Four genes, which are orthologous to human, were found
Autor:
Guo Li, Jinfang Zhang, Xiao-ai Zhang, Hsiang-Fu Kung, Chu-yan Chan, Marie Chia-mi Lin, Ping-Chung Leung, David T. Yew, Ming-Liang He
Publikováno v:
Phytotherapy Research. 24:571-576
Fructus Ligustri Lucidi (FLL) has been used in traditional Chinese medicine for over 1000 years. The ethanol extract of FLL (EFLL) has been shown to be a potential candidate in the prevention and treatment of osteoporosis. The present study aimed to
Autor:
Ming-Liang He, Marie C. Lin, Henry Lik-Yuen Chan, Yangchao Chen, Hsiang-Fu Kung, Zheng Liu, Qingming Dong, Joseph J.Y. Sung, Chu-yan Chan
Publikováno v:
Journal of Virological Methods. 159:135-140
The present study aimed to construct a 1.5X hepatitis B virus (HBV) replication system in vitro that could generate high level of HBV viruses. This system would help compare the replication capacity among the virus strains associated with high and lo
Autor:
Dexian Zheng, Yangchao Chen, Xintao Shuai, Marie C. Lin, Yi Li, Hsiang-Fu Kung, Bing Liang, Chu-yan Chan, Ying Peng, Ming-Liang He, Xiang-Ping Li
Publikováno v:
Biomaterials. 30:4014-4020
Combined treatment using nonviral agent-mediated enzyme/prodrug therapy and immunotherapy had been proposed as a powerful alternative method of cancer therapy. The present study was aimed to evaluate the cytotoxicity in vitro and the therapeutic effi
Autor:
Ping-Chung Leung, Chu-yan Chan, Jin-fang Zhang, Guo Li, Yaou Zhang, Qi Dong, Chun-ling Meng, Ming-Liang He, Hsiang-Fu Kung
Publikováno v:
Phytomedicine. 16:521-529
Introduction In China Herba Epimedii is one of the most common herbs that could be prescribed for treating osteoporosis. It is known to increase the overall mineral content, therefore, to promote bone formation and to increase lumbar bone mineral den
Autor:
Zheng Liu, Christopher H.K. Cheng, Hong-Xi Xu, Xin Wang, Hua Wang, Yangchao Chen, David T. Yew, Quan-Bin Han, Joseph J.Y. Sung, Ming-Liang He, Hsiang-Fu Kung, Chu-yan Chan, Marie C.M. Lin
Publikováno v:
PROTEOMICS. 9:242-253
Gamboge has been developed as an injectable drug for cancer treatment in China. In this study, the inhibition ratio and their IC(50) values of two derivatives from Gamboge in hepatocellular carcinoma (HCC) were determined. Proteomic approach was empl
Autor:
Zhi Li, Hong Yao, Jian-Dong Huang, Yan Ma, Hsiang-Fu Kung, Ying Peng, Yangchao Chen, Marie C. Lin, Qingming Dong, Bo-Jian Zheng, Kwok Yun Yuen, Chu-yan Chan, Ming-Liang He, Joseph J.Y. Sung
Publikováno v:
The Journal of Gene Medicine
Background Interferon-α2 (IFNα2) is routinely used for anti-hepatitis B virus (HBV) treatment. However, the therapeutic efficiency is unsatisfactory, particularly in East Asia. Such inefficiency might be a result of the short half-life, relatively