Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Chu Wei Kuo"'
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-8 (2022)
A 29-amino acid sequence in the N-terminal domain of LAMP-1 promotes its Lewis X glycosylation and is embeddable to other proteins for Lewis X glycoengineering.
Externí odkaz:
https://doaj.org/article/8859b6183d7c47e39ccbd4e7cf971a14
Autor:
Gilormini, Pierre-André, Thota, V. Narasimharao, Fers-Lidou, Anthony, Ashmus, Roger A., Nodwell, Matthew, Brockerman, Jacob, Chu-Wei Kuo, Yang Wang, Gray, Taylor E., Nitin, McDonagh, Anthony W., Shih-Yun Guu, Ertunc, Nursah, Yeo, Dominick, Zandberg, Wesley F., Kay-Hooi Khoo, Britton, Robert, Vocadlo, David J.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 7/2/2024, Vol. 121 Issue 27, p1-10, 80p
Autor:
Fumiko Umezawa, Makoto Natsume, Shigeki Fukusada, Kazuki Nakajima, Fumiya Yamasaki, Hiroto Kawashima, Chu-Wei Kuo, Kay-Hooi Khoo, Takaya Shimura, Hirokazu Yagi, Koichi Kato
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 12, p 6662 (2022)
The dystrophin–glycoprotein complex connects the cytoskeleton with base membrane components such as laminin through unique O-glycans displayed on α-dystroglycan (α-DG). Genetic impairment of elongation of these glycans causes congenital muscular
Externí odkaz:
https://doaj.org/article/b4283df908144867b7894da60a7a2d22
Autor:
Jung-Mao Hsu, Weiya Xia, Yi-Hsin Hsu, Li-Chuan Chan, Wen-Hsuan Yu, Jong-Ho Cha, Chun-Te Chen, Hsin-Wei Liao, Chu-Wei Kuo, Kay-Hooi Khoo, Jennifer L. Hsu, Chia-Wei Li, Seung-Oe Lim, Shih-Shin Chang, Yi-Chun Chen, Guo-xin Ren, Mien-Chie Hung
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
PD-L1 accumulates on cancer stem cells and favours immune evasion but the mechanism underlying this accumulation are unknown. Here the authors show that epithelial-mesenchymal transition induces glycosylation and stabilisation of PD-L1; antagonising
Externí odkaz:
https://doaj.org/article/b6e5e0697fa048aeb6392035c75e7d85
Autor:
Alice L. Yu, John Yu, Li-Mei Pai, Kay-Hooi Khoo, Chu-Wei Kuo, Sheng-Hung Wang, Hui-Ling Yeo, Jung‐Tung Hung, Tan-Chi Fan, Wen-Der Lin
Supplementary figure S1-S5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::391ee53675c23ff053122051b6501302
https://doi.org/10.1158/2326-6066.22543816
https://doi.org/10.1158/2326-6066.22543816
Autor:
Alice L. Yu, John Yu, Li-Mei Pai, Kay-Hooi Khoo, Chu-Wei Kuo, Sheng-Hung Wang, Hui-Ling Yeo, Jung‐Tung Hung, Tan-Chi Fan, Wen-Der Lin
Altered glycosylations, which are associated with expression and activities of glycosyltransferases, can dramatically affect the function of glycoproteins and modify the behavior of tumor cells. ST3GAL1 is a sialyltransferase that adds sialic acid to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a0b3fc82b6bd451c552ec3d05a6ba19
https://doi.org/10.1158/2326-6066.c.6550417
https://doi.org/10.1158/2326-6066.c.6550417
Autor:
Chia-Wei Li, Seung-Oe Lim, Weiya Xia, Heng-Huan Lee, Li-Chuan Chan, Chu-Wei Kuo, Kay-Hooi Khoo, Shih-Shin Chang, Jong-Ho Cha, Taewan Kim, Jennifer L. Hsu, Yun Wu, Jung-Mao Hsu, Hirohito Yamaguchi, Qingqing Ding, Yan Wang, Jun Yao, Cheng-Chung Lee, Hsing-Ju Wu, Aysegul A. Sahin, James P. Allison, Dihua Yu, Gabriel N. Hortobagyi, Mien-Chie Hung
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
Programmed Death ligand-1 (PD-L1) protein mediates immune suppression in cancer. Here, the authors show that in breast cancer, PD-L1 expression can be up regulated post-translationally by glycosylation, which in turn acts through inhibiting GSK3β-me
Externí odkaz:
https://doaj.org/article/95bbbbb825d74f9a9d75ce9718db0cfa
Autor:
Uwe Möginger, Sonja Grunewald, René Hennig, Chu-Wei Kuo, Falko Schirmeister, Harald Voth, Erdmann Rapp, Kay-Hooi Khoo, Peter H. Seeberger, Jan C. Simon, Daniel Kolarich
Publikováno v:
Frontiers in Oncology, Vol 8 (2018)
The glycome of one of the largest and most exposed human organs, the skin, as well as glycan changes associated with non-melanoma skin cancers have not been studied in detail to date. Skin cancers such as basal cell carcinoma (BCC) and squamous cell
Externí odkaz:
https://doaj.org/article/861d7b34bf424f7ca4632517589bbdaf
Autor:
Jhon R. Enterina, Matthew S. Macauley, Chris D. St. Laurent, Kay-Hooi Khoo, Abhishek Bhattacherjee, Chu-Wei Kuo, Wesley F. Zandberg, Fahima Mozaneh, Emily Rodrigues, Parisa Raeisimakiani, Gour Chand Daskhan, Jaesoo Jung, H Nitin, Po-Han Lin, Xuefei Huang, Lara K. Mahal, Duong T Bui, John S. Klassen
Publikováno v:
ACS Chemical Biology. 16:2673-2689
The immunomodulatory family of Siglecs recognize sialic acid-containing glycans as ‘self’, which is exploited in cancer for immune-evasion. The biochemical nature of Siglec ligands remains incompletely understood with emerging evidence suggesting