Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Chu Lan Lao"'
Autor:
Matteo Puglisi, Chu Lan Lao, Gulzar Wani, Giacomo Masserdotti, Riccardo Bocchi, Magdalena Götz
Publikováno v:
Cells, Vol 13, Iss 17, p 1408 (2024)
Direct neuronal reprogramming is a promising approach to replace neurons lost due to disease via the conversion of endogenous glia reacting to brain injury into neurons. However, it is essential to demonstrate that the newly generated neurons origina
Externí odkaz:
https://doaj.org/article/c35688423d2d42bfb689491aa03e051d
Parkinson's disease motor symptoms rescue by CRISPRa‐reprogramming astrocytes into GABAergic neurons
Autor:
Jessica Giehrl‐Schwab, Florian Giesert, Benedict Rauser, Chu Lan Lao, Sina Hembach, Sandrine Lefort, Ignacio L Ibarra, Christina Koupourtidou, Malte Daniel Luecken, Dong‐Jiunn Jeffery Truong, Judith Fischer‐Sternjak, Giacomo Masserdotti, Nilima Prakash, Jovica Ninkovic, Sabine M Hölter, Daniela M Vogt Weisenhorn, Fabian J Theis, Magdalena Götz, Wolfgang Wurst
Publikováno v:
EMBO Molecular Medicine, Vol 14, Iss 5, Pp 1-20 (2022)
Abstract Direct reprogramming based on genetic factors resembles a promising strategy to replace lost cells in degenerative diseases such as Parkinson's disease. For this, we developed a knock‐in mouse line carrying a dual dCas9 transactivator syst
Externí odkaz:
https://doaj.org/article/d6d64f7bdd884a3b9299b97fa956cf9b
Autor:
Chu Lan Lao, 劉珠蘭
101
The neurotransmitter dopamine acts on the subventricular zone (SVZ) to regulate both prenatal and postnatal neurogenesis, in particular through D3 receptor (D3R) subtype. In this study, we explored the cellular mechanism(s) underlying D3R-me
The neurotransmitter dopamine acts on the subventricular zone (SVZ) to regulate both prenatal and postnatal neurogenesis, in particular through D3 receptor (D3R) subtype. In this study, we explored the cellular mechanism(s) underlying D3R-me
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/09230289041787875551
Autor:
Chu Lan Lao, 劉珠蘭
96
In the adult mammalian central nervous system, neural stem cells (NSCs) persist mainly in the subventricular zone (SVZ). Dopamine D3 receptors (D3R) are abundantly expressed in the SVZ during the brain development until adulthood, thereby sup
In the adult mammalian central nervous system, neural stem cells (NSCs) persist mainly in the subventricular zone (SVZ). Dopamine D3 receptors (D3R) are abundantly expressed in the SVZ during the brain development until adulthood, thereby sup
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/01138582102327842261
Autor:
Simon Chang, Federica Fermani, Chu-Lan Lao, Lianyun Huang, Mira Jakovcevski, Rossella Di Giaimo, Miriam Gagliardi, Danusa Menegaz, Alexander Adrian Hennrich, Michael Ziller, Matthias Eder, Rüdiger Klein, Na Cai, Jan M. Deussing
An adaptive stress response involves various mediators and circuits orchestrating a complex interplay of physiological, emotional and behavioural adjustments. We identified a population of corticotropin-releasing hormone (CRH) neurons in the lateral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc648b51bf4eff15280a972a8e7046a1
https://doi.org/10.1101/2022.03.15.484057
https://doi.org/10.1101/2022.03.15.484057
Autor:
Simon Chang, Federica Fermani, Chu-Lan Lao, Lianyun Huang, Mira Jakovcevski, Rossella Di Giaimo, Miriam Gagliardi, Danusa Menegaz, Alexandru Adrian Hennrich, Michael Ziller, Matthias Eder, Rüdiger Klein, Na Cai, Jan M. Deussing
Publikováno v:
Sci. Adv. 8:eabo1023 (2022)
Science advances 8(46), eabo1023 (2022). doi:10.1126/sciadv.abo1023
Science advances 8(46), eabo1023 (2022). doi:10.1126/sciadv.abo1023
Science advances 8(46), eabo1023 (2022). doi:10.1126/sciadv.abo1023
Published by American Association for the Advancement of Science, Washington, DC [u.a.]
Published by American Association for the Advancement of Science, Washington, DC [u.a.]
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db2cd50af4badce0d5b75bd6cea37e93
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=66764
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=66764
Autor:
Agne Vaiceliunaite, Milad Hobbi Mobarhan, Chu Lan Lao, Sinem Erisken, Felix A Schneider-Soupiadis, Gregory Born, Martin A. Spacek, Gaute T. Einevoll, Laura Busse
Publikováno v:
Nat. Neurosci., 1711–1720 (2021)
En route from the retina to the cortex, visual information passes through the dorsolateral geniculate nucleus (dLGN) of the thalamus, where extensive corticothalamic (CT) feedback has been suggested to modulate spatial processing. How this modulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39f657b894c89bc3dca9926a4d40f9f2
https://pubmed.ncbi.nlm.nih.gov/34764474
https://pubmed.ncbi.nlm.nih.gov/34764474
Autor:
Chu Lan Lao, Agne Klein, Gregory Born, Martin A. Spacek, Laura Busse, Sinem Erisken, Gaute T. Einevoll, Felix A. Schneider, Milad Hobbi Mobarhan
En route from retina to cortex, visual information passes through the dorsolateral geniculate nucleus of the thalamus (dLGN), where extensive corticothalamic (CT) feedback has been suggested to modulate spatial processing. How this modulation arises
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::591d516c456e01b751ccdce1daf5fd08
https://doi.org/10.1101/2020.05.19.104000
https://doi.org/10.1101/2020.05.19.104000
Autor:
Nicola Mattugini, Volker Scheuss, Chu Lan Lao, Olof Torper, Magdalena Götz, Riccardo Bocchi, Gianluca Luigi Russo
Publikováno v:
Neuron 103, 1086-1095.e5 (2019)
Neuron
Neuron
Summary Astrocytes are particularly promising candidates for reprogramming into neurons, as they maintain some of the original patterning information from their radial glial ancestors. However, to which extent the position of astrocytes influences th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dece376b0f29c67b9ce96dd54e21ddc9
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=56958
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=56958
Publikováno v:
Glia. 61:475-489
The neurotransmitter dopamine acts on the subventricular zone (SVZ) to regulate both prenatal and postnatal neurogenesis, in particular through D(3) receptor (D(3) R) subtype. In this study, we explored the cellular mechanism(s) underlying D(3) R-med
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::153c301e9886bc2dafcf720cd9c8135a
https://doi.org/10.1002/glia.22449
https://doi.org/10.1002/glia.22449