Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Chrysi Kanellopoulou"'
Autor:
Cecile Geuijen, Paul Tacken, Liang-Chuan Wang, Rinse Klooster, Pieter Fokko van Loo, Jing Zhou, Arpita Mondal, Yao-bin Liu, Arjen Kramer, Thomas Condamine, Alla Volgina, Linda J. A. Hendriks, Hans van der Maaden, Eric Rovers, Steef Engels, Floris Fransen, Renate den Blanken-Smit, Vanessa Zondag-van der Zande, Abdul Basmeleh, Willem Bartelink, Ashwini Kulkarni, Wilfred Marissen, Cheng-Yen Huang, Leslie Hall, Shane Harvey, Soyeon Kim, Marina Martinez, Shaun O’Brien, Edmund Moon, Steven Albelda, Chrysi Kanellopoulou, Shaun Stewart, Horacio Nastri, Alexander B. H. Bakker, Peggy Scherle, Ton Logtenberg, Gregory Hollis, John de Kruif, Reid Huber, Patrick A. Mayes, Mark Throsby
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
The anti-tumour effect of immune checkpoint inhibitors is potentiated by CD137 agonists in preclinical models, but translation of these results to the clinical practice is hampered by toxicity. Authors describe here a human CD137xPD-L1 bispecific ant
Externí odkaz:
https://doaj.org/article/4044cbbb9c1d4937ac08f857eba69b30
Autor:
Jing Zhou, Mark Throsby, Lex Bakker, Arpita Mondal, Wilfred Marissen, Paul Tacken, Steef Engels, Liang-Chuan Wang, Patrick Mayes, Cecile Geuijen, Rinse Klooster, Pieter Fokko Van Loo, Yao-Bin Liu, Arjen Kramer, Thomas Condamine, Alla Volgina, Linda Hendriks, Hans van der Maaden, Eric Rovers, Floris Fransen, Renate den Blanken-Smit, Vanessa Zondag-van der Zande, Abdul Basmeleh, Willem Bartelink, Ashwini Kulkarni, Cheng-Yen Huang, Leslie Hall, Shane Harvey, Chrysi Kanellopoulou, Shaun Stewart, Horacio Nastri, Ton Logtenberg, Simon Plyte
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/3ac9962628b4422ba42992da2d11038e
Autor:
Chrysi Kanellopoulou, Stefan A. Muljo
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
How a single genome can give rise to many different transcriptomes and thus all the different cell lineages in the human body is a fundamental question in biology. While signaling pathways, transcription factors, and chromatin architecture, to name a
Externí odkaz:
https://doaj.org/article/66b87d930804454f9ea74cd2fc8f5c1b
Autor:
Gregory Hollis, Wenqing Yao, Reid Huber, Peggy Scherle, Jeff Jackson, Swamy Yeleswaram, Cindy Marando, Ryan Geschwindt, Pramod Thekkat, Yue Zhang, Christina Stevens, Luping Lin, Darlise DiMatteo, Mark Rupar, Gengjie Yang, Chrysi Kanellopoulou, Stephen Rubin, Kevin O'Hayer, Maxim Soloviev, Sharon Diamond, Jingwei Li, Yan-ou Yang, Maryanne Covington, Elham Behshad, Kanishk Kapilashrami, Nina Zolotarjova, Alla Volgina, Hao Liu, Susan Spitz, Jonathan Rios-Doria, Richard Wynn, Phillip C.C. Liu, Liang-Chuan S. Wang, Liangxing Wu, Holly K. Koblish
Supplementary Table from Characterization of INCB086550: A Potent and Novel Small-Molecule PD-L1 Inhibitor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76bbcf100cd3199695d65a7a2d3df77e
https://doi.org/10.1158/2159-8290.22540981.v1
https://doi.org/10.1158/2159-8290.22540981.v1
Autor:
Gregory Hollis, Wenqing Yao, Reid Huber, Peggy Scherle, Jeff Jackson, Swamy Yeleswaram, Cindy Marando, Ryan Geschwindt, Pramod Thekkat, Yue Zhang, Christina Stevens, Luping Lin, Darlise DiMatteo, Mark Rupar, Gengjie Yang, Chrysi Kanellopoulou, Stephen Rubin, Kevin O'Hayer, Maxim Soloviev, Sharon Diamond, Jingwei Li, Yan-ou Yang, Maryanne Covington, Elham Behshad, Kanishk Kapilashrami, Nina Zolotarjova, Alla Volgina, Hao Liu, Susan Spitz, Jonathan Rios-Doria, Richard Wynn, Phillip C.C. Liu, Liang-Chuan S. Wang, Liangxing Wu, Holly K. Koblish
Supplementary Figure from Characterization of INCB086550: A Potent and Novel Small-Molecule PD-L1 Inhibitor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::170fab3f863c9be0aad6f9e19f25879b
https://doi.org/10.1158/2159-8290.22540984.v1
https://doi.org/10.1158/2159-8290.22540984.v1
Autor:
Gregory Hollis, Wenqing Yao, Reid Huber, Peggy Scherle, Jeff Jackson, Swamy Yeleswaram, Cindy Marando, Ryan Geschwindt, Pramod Thekkat, Yue Zhang, Christina Stevens, Luping Lin, Darlise DiMatteo, Mark Rupar, Gengjie Yang, Chrysi Kanellopoulou, Stephen Rubin, Kevin O'Hayer, Maxim Soloviev, Sharon Diamond, Jingwei Li, Yan-ou Yang, Maryanne Covington, Elham Behshad, Kanishk Kapilashrami, Nina Zolotarjova, Alla Volgina, Hao Liu, Susan Spitz, Jonathan Rios-Doria, Richard Wynn, Phillip C.C. Liu, Liang-Chuan S. Wang, Liangxing Wu, Holly K. Koblish
Blocking the activity of the programmed cell death protein 1 (PD-1) inhibitory receptor with therapeutic antibodies against either the ligand (PD-L1) or PD-1 itself has proven to be an effective treatment modality for multiple cancers. Contrasting wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6486db56a65286928bd5907136280e12
https://doi.org/10.1158/2159-8290.c.6549529
https://doi.org/10.1158/2159-8290.c.6549529
Autor:
Gregory Hollis, Wenqing Yao, Reid Huber, Peggy Scherle, Jeff Jackson, Swamy Yeleswaram, Cindy Marando, Ryan Geschwindt, Pramod Thekkat, Yue Zhang, Christina Stevens, Luping Lin, Darlise DiMatteo, Mark Rupar, Gengjie Yang, Chrysi Kanellopoulou, Stephen Rubin, Kevin O'Hayer, Maxim Soloviev, Sharon Diamond, Jingwei Li, Yan-ou Yang, Maryanne Covington, Elham Behshad, Kanishk Kapilashrami, Nina Zolotarjova, Alla Volgina, Hao Liu, Susan Spitz, Jonathan Rios-Doria, Richard Wynn, Phillip C.C. Liu, Liang-Chuan S. Wang, Liangxing Wu, Holly K. Koblish
Supplementary Data from Characterization of INCB086550: A Potent and Novel Small-Molecule PD-L1 Inhibitor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5739e2f7911a281a155113d1f5d765bd
https://doi.org/10.1158/2159-8290.22540987
https://doi.org/10.1158/2159-8290.22540987
Autor:
Han Myint, Satish Shah, Martin Gutierrez, Emese Zsiros, Megan Nelson, Stephanie Zeidan, Nadia Myrthil, Aaron Morawski, Alina Barbu, Jahangheer Shaik, Chelsea Zhou, Chrysi Kanellopoulou, Ron Copeland, Zachary Cusumano, Dallas Flies, Solomon Langermann, Patricia Lorusso, Kunle Odunsi
Publikováno v:
Regular and Young Investigator Award Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be4708048023744c3dd251b6bad8f59e
https://doi.org/10.1136/jitc-2022-sitc2022.0748
https://doi.org/10.1136/jitc-2022-sitc2022.0748
Autor:
Yikun Yao, Girak Kim, Samantha Shafer, Zuojia Chen, Satoshi Kubo, Yanlong Ji, Jialie Luo, Weiming Yang, Sebastian P. Perner, Chrysi Kanellopoulou, Ann Y. Park, Ping Jiang, Jian Li, Safa Baris, Elif Karakoc Aydiner, Deniz Ertem, Daniel J. Mulder, Neil Warner, Anne M. Griffiths, Chani Topf-Olivestone, Michal Kori, Lael Werner, Jodie Ouahed, Michael Field, Chengyu Liu, Benjamin Schwarz, Catharine M. Bosio, Sundar Ganesan, Jian Song, Henning Urlaub, Thomas Oellerich, Stacy A. Malaker, Lixin Zheng, Carolyn R. Bertozzi, Yu Zhang, Helen Matthews, Will Montgomery, Han-Yu Shih, Jiansheng Jiang, Marcus Jones, Aris Baras, Alan Shuldiner, Claudia Gonzaga-Jauregui, Scott B. Snapper, Aleixo M. Muise, Dror S. Shouval, Ahmet Ozen, Kuan-Ting Pan, Chuan Wu, Michael J. Lenardo
Publikováno v:
Cell
Intestinal mucus forms the first line of defense against bacterial invasion while providing nutrition to support microbial symbiosis. How the host controls mucus barrier integrity and commensalism is unclear. We show that terminal sialylation of glyc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e24c072df876973c21dcc6ca3d676e4c
https://europepmc.org/articles/PMC9088855/
https://europepmc.org/articles/PMC9088855/
Autor:
Musa Karakukcu, Ratnadeep Mukherjee, Lynne A. Wolfe, Aaron Morawski, Lixin Zheng, Niraj C. Patel, Samuel D. Chauvin, Helen F. Matthews, Brian Sellers, Julio C. Orrego-Arango, Tingyan He, Susan Price, Alexandre G. R. Day, Pankaj Mehta, Les R. Folio, Giulia Notarangelo, Jordan S. Orange, James T. Anibal, Evan M. Masutani, Pam Angelus, Chrysi Kanellopoulou, Claudia M. Trujillo-Vargas, Sally Hunsberger, David E. Kleiner, Suk See De Ravin, Jenna R.E. Bergerson, Michael J. Lenardo, Devika Kapuria, Matthew Biancalana, Gulbu Uzel, Mami Matsuda-Lennikov, Sebastian Gutierrez-Hincapie, Alex George, Camilo Toro, Jeffrey I. Cohen, Juan Zou, Ivan K. Chinn, Juan C. Ravell, Ping Jiang, Harry L. Malech, William A. Gahl, Ekrem Unal, Grégoire Altan-Bonnet, Matthias Mann, Kyle Binder, Turkan Patiroglu, Stefania Pittaluga, Astin Powers, Helen C. Su, Kimiyo Raymond, Marc G. Ghany, Sally J. Deeb, José Luis Franco, V. Koneti Rao
Publikováno v:
The Journal of clinical investigation, vol 130, iss 1
J Clin Invest
J Clin Invest
X-linked immunodeficiency with magnesium defect, EBV infection, and neoplasia (XMEN) disease are caused by deficiency of the magnesium transporter 1 (MAGT1) gene. We studied 23 patients with XMEN, 8 of whom were EBV naive. We observed lymphadenopathy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff10b75c10af59e6c310b4a286c63be4
https://doi.org/10.1172/jci131116
https://doi.org/10.1172/jci131116