Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Chronological ageing"'
Autor:
Shaun H. Speldewinde, Chris M. Grant
Publikováno v:
Microbial Cell, Vol 4, Iss 4, Pp 127-132 (2017)
Ageing involves a time-dependent decline in a variety of intracellular mechanisms and is associated with cellular senescence. This can be exacerbated by prion diseases which can occur in a sporadic manner, predominantly during the later stages of lif
Externí odkaz:
https://doaj.org/article/8c0be892dee94ae89c11cb2785cafcb6
Autor:
N. V. Gomyranova, V. A. Metelskaya, O. N. Tkacheva, I. N. Ozerova, N. V. Perova, O. V. Alexandrovitch
Publikováno v:
Кардиоваскулярная терапия и профилактика, Vol 14, Iss 3, Pp 65-69 (2015)
Aim. To study the relation of pulse wave velocity (PWV) as arterial stiffness index, and the level of biochemical factors elevation, that are involved in atherothrombogenesis and play role in determination of cardiovascular risk in various age patien
Externí odkaz:
https://doaj.org/article/52618c9c81ec4442b5d30ea39736d5a9
Autor:
Anindita Majumdar
Publikováno v:
Anthropology & Aging, Vol 42, Iss 1, Pp 49-65 (2021)
Through a mapping of field data collected from two parts of India: Hisar in North India and Hyderabad in South India, this paper looks at the ways in which reproductive decline and ageing have become part of the discourse on assisted reproduction in
Publikováno v:
Cells, Vol 8, Iss 1, p 54 (2019)
Telomeres with G-rich repetitive DNA and particular proteins as special heterochromatin structures at the termini of eukaryotic chromosomes are tightly maintained to safeguard genetic integrity and functionality. Telomerase as a specialized reverse t
Externí odkaz:
https://doaj.org/article/e854d5bc2a274053b2f0a0fda99de414
Autor:
Jonatan R. Ruiz, Francisco J. Amaro-Gahete, Manuel J. Castillo, Alejandro De-la-O, Lucas Jurado-Fasoli
Publikováno v:
Aging (Albany NY)
S-klotho, the shed form of α-klotho, is thought to be an ageing suppressor with functions related to the physiology of energy metabolism. However, it remains unknown whether ageing biomarkers such as S-klotho and/or chronological ageing are associat
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1865:1822-1830
Cellular senescence is the permanent cell cycle arrest induced either by chronological ageing or extrinsic stimuli. Recent researches have identified cellular senescence as an important mechanism for atherosclerosis, which is the essential pathophysi
Autor:
Chisa Okada, Ayumi Sasaki, Yu Kakimoto, Hideo Tsukamoto, Ryoko Nagao, Noboru Kawabe, Motoki Osawa
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-8 (2019)
Scientific Reports
Scientific Reports
Lipofuscin is an intracellular aggregate of highly oxidized proteins that cannot be digested in the ubiquitin-proteasome system and accumulate mainly in lysosomes, especially in aged cells and pathological conditions. However, no systematic study has
Autor:
Angela S. Koh, Jean-Paul Kovalik
Publikováno v:
ESC Heart Failure
ESC Heart Failure, Vol 8, Iss 3, Pp 1738-1750 (2021)
ESC Heart Failure, Vol 8, Iss 3, Pp 1738-1750 (2021)
The purpose of this review is to explore how metabolomics can help uncover new biomarkers and mechanisms for cardiovascular ageing. Cardiovascular ageing refers to cardiovascular structural and functional alterations that occur with chronological age
Publikováno v:
BMJ Global Health, Vol 5, Iss 4 (2020)
BMJ Global Health
BMJ Global Health
Although people are living longer, there is no discernible pattern about the quality of life in an increasing lifespan. This restricts our capacity to predict and prepare for the consequences of population ageing. Accordingly, we propose a population
Autor:
Tomasz Zegarski, Maciej Nowacki, Katarzyna Pietkun, Barbara Zegarska, Krystyna Romańska-Gocka, Paulina Giemza-Kucharska
Publikováno v:
Advances in Dermatology and Allergology, Vol 34, Iss 3, Pp 260-267 (2017)
Advances in Dermatology and Allergology/Postȩpy Dermatologii i Alergologii
Advances in Dermatology and Allergology/Postȩpy Dermatologii i Alergologii
Introduction : During the process of skin ageing, changes occur in all skin layers and all cells, including the Langerhans cells. Aim: To assess whether any quantitative difference in the number of CD1a+ LC cells/mm 2 and HLA-DR+ LC cells/mm 2 as wel