Zobrazeno 1 - 10
of 106
pro vyhledávání: '"Chronic mild stress (CMS)"'
Autor:
Yaling Fu, Xiangfei Guo, Rui Yang, Hao Feng, Xueyong Yin, Shuang Wang, Li Song, Xi Wang, Penghui Zhao, Sheng Wang, Yun Shi, Haishui Shi
Publikováno v:
Frontiers in Psychiatry, Vol 14 (2023)
BackgroundThe pathogenesis of depression is closely related to changes in hippocampal synaptic plasticity; however, the underlying mechanism is still unclear. Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAIAP2), a postsynaptic scaff
Externí odkaz:
https://doaj.org/article/597fc973a5724fdaa6ae79111fe82126
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 16 (2022)
Exposure to severe, uncontrollable and long-lasting stress is a strong risk factor for the development of numerous mental and somatic disorders. Animal studies document that chronic stress can alter neuronal morphology and functioning in limbic brain
Externí odkaz:
https://doaj.org/article/574b85e83fef4bd2b76183df03a25b3e
Akademický článek
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Publikováno v:
Saudi Pharmaceutical Journal, Vol 24, Iss 5, Pp 571-578 (2016)
Background: Fluoxetine, a selective serotonin re-uptake inhibitor (SSRI), has been proposed to be more effective as an antidepressive drug as compared to other SSRIs. After chronic SSRI administration, the increase in synaptic levels of 5-HT leads to
Externí odkaz:
https://doaj.org/article/c22e6e4d606a4700a427e882f19c7e16
Chronic mild stress paradigm as a rat model of depression: facts, artifacts, and future perspectives
Autor:
Tatyana Strekalova, Yanzhi Liu, Daniel Kiselev, Sharafuddin Khairuddin, Jennifer Lok Yu Chiu, Justin Lam, Ying-Shing Chan, Dmitrii Pavlov, Andrey Proshin, Klaus-Peter Lesch, Daniel C. Anthony, Lee Wei Lim
Publikováno v:
Psychopharmacology
Rationale The chronic mild stress (CMS) paradigm was first described almost 40 years ago and has become a widely used model in the search for antidepressant drugs for major depression disorder (MDD). It has resulted in the publication of almost 1700
Chronic mild stress paradigm as a rat model of depression: facts, artifacts, and future perspectives
Publikováno v:
Psychopharmacology. 239(3):663-693
Rationale The chronic mild stress (CMS) paradigm was first described almost 40 years ago and has become a widely used model in the search for antidepressant drugs for major depression disorder (MDD). It has resulted in the publication of almost 1700
Publikováno v:
Kaohsiung Journal of Medical Sciences, Vol 31, Iss 12, Pp 605-612 (2015)
Natural products have been widely reported as effective therapeutic alternatives for treatment of depression. Sanyuansan is a compound recipe composed of ginseng total saponins, fish oil, and valeriana. The aims of this study were to validate whether
Externí odkaz:
https://doaj.org/article/6f0b42a9cdad43538c1ecc41be3016ca
Publikováno v:
eLife, Vol 7 (2017)
Dopamine neurons in the ventral tegmental area (VTA) are powerful regulators of depression-related behavior. Dopamine neuron activity is altered in chronic stress-based models of depression, but the underlying mechanisms remain incompletely understoo
Externí odkaz:
https://doaj.org/article/4ffb1175c6bc4c5ea38a965036dc0b29
Autor:
Renata Pukło, Magdalena Łasoń, Władysława A. Daniel, Mariusz Papp, Ewa Bromek, Anna Haduch, Marta Rysz, Monika Niemczyk, Piotr Gruca
Publikováno v:
Pharmacological Reports
Background The aim of our research was to determine the effects of chronic treatment with the atypical antidepressant agomelatine on the expression and activity of liver cytochrome P450 (CYP) in the chronic mild stress (CMS) model of depression, and
Publikováno v:
Csabai, D, Sebők-Tornai, A, Wiborg, O & Czéh, B 2022, ' A Preliminary Quantitative Electron Microscopic Analysis Reveals Reduced Number of Mitochondria in the Infralimbic Cortex of Rats Exposed to Chronic Mild Stress ', Frontiers in behavioral neuroscience, vol. 16, 885849 . https://doi.org/10.3389/fnbeh.2022.885849
Exposure to severe, uncontrollable and long-lasting stress is a strong risk factor for the development of numerous mental and somatic disorders. Animal studies document that chronic stress can alter neuronal morphology and functioning in limbic brain