Zobrazeno 1 - 10
of 587
pro vyhledávání: '"Chromosome Structure and Function"'
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 13, Iss 5, p e1006776 (2017)
PLoS Genetics, Vol 13, Iss 5, p e1006776 (2017)
The posttranslational modifiers SUMO and ubiquitin critically regulate the DNA damage response (DDR). Important crosstalk between these modifiers at DNA lesions is mediated by the SUMO-targeted ubiquitin ligase (STUbL), which ubiquitinates SUMO chain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2d59577f578bce9f339204f91e92af9
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 12, p e1009669 (2021)
PLoS Computational Biology
PLoS Computational Biology
There is a growing realization that multi-way chromatin contacts formed in chromosome structures are fundamental units of gene regulation. However, due to the paucity and complexity of such contacts, it is challenging to detect and identify them usin
Autor:
Xiakun Chu, Jin Wang
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 11, p e1009596 (2021)
PLoS Computational Biology
PLoS Computational Biology
Cancer reflects the dysregulation of the underlying gene network, which is strongly related to the 3D genome organization. Numerous efforts have been spent on experimental characterizations of the structural alterations in cancer genomes. However, th
Autor:
William A. Scott, Erum Z. Dhanji, Grant S. Stewart, Mila Mirceta, Anne-Claude Gingras, Boris J. A. Dyakov, Christopher E. Pearson, Jonathon S. Asa, Ema S. Dreseris, Laura J. Grange, Eric I. Campos
Publikováno v:
PLoS Genetics, Vol 17, Iss 11, p e1009909 (2021)
PLoS Genetics
PLoS Genetics
The ATRX ATP-dependent chromatin remodelling/helicase protein associates with the DAXX histone chaperone to deposit histone H3.3 over repetitive DNA regions. Because ATRX-protein interactions impart functions, such as histone deposition, we used prox
Autor:
Cleusa Yoshiko Nagamachi, Ana Cristina Mendes-Oliveira, Patricia Caroline Mary O’Brien, Malcolm A. Ferguson-Smith, Lena Geise, Vergiana dos Santos Paixão, Rogério V. Rossi, Willam Oliveira da Silva, Julio Cesar Pieczarka, Pablo Suárez
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 10, p e0258474 (2021)
PLoS ONE, Vol 16, Iss 10, p e0258474 (2021)
Rhipidomys (Sigmodontinae, Thomasomyini) has 25 recognized species, with a wide distribution ranging from eastern Panama to northern Argentina. Cytogenetic data has been described for 13 species with 12 of them having 2n = 44 with a high level of aut
Autor:
Andrea Lukacs, Andreas W. Thomae, Peter Krueger, Rupam Choudhury, Natalia Y. Kochanova, Wasim Aftab, Ignasi Forné, Axel Imhof, Tamas Schauer, Anuroop Venkateswaran Venkatasubramani
Publikováno v:
Lukacs, A, Thomae, A W, Krueger, P, Schauer, T, Venkatasubramani, A V, Kochanova, N Y, Aftab, W, Choudhury, R, Forne, I & Imhof, A 2021, ' The integrity of the HMR complex is necessary for centromeric binding and reproductive isolation in Drosophila ', PLoS Genetics, vol. 17, no. 8, e1009744 . https://doi.org/10.1371/journal.pgen.1009744
PLoS Genetics
PLoS Genetics, Vol 17, Iss 8, p e1009744 (2021)
PLoS Genetics
PLoS Genetics, Vol 17, Iss 8, p e1009744 (2021)
Postzygotic isolation by genomic conflict is a major cause for the formation of species. Despite its importance, the molecular mechanisms that result in the lethality of interspecies hybrids are still largely unclear. The genus Drosophila, which cont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c27dc66275d1fd992ff4ccc96f01d57
https://www.pure.ed.ac.uk/ws/files/258552829/journal.pgen.1009744.pdf
https://www.pure.ed.ac.uk/ws/files/258552829/journal.pgen.1009744.pdf
Autor:
Letizia Li Piani, Marco Reschini, Edgardo Somigliana, Stefania Ferrari, Andrea Busnelli, Paola Viganò, Chiara Favero, Benedetta Albetti, Mirjam Hoxha, Valentina Bollati
Publikováno v:
PLoS ONE
PLoS ONE, Vol 17, Iss 1, p e0261591 (2022)
PLoS ONE, Vol 17, Iss 1 (2022)
PLoS ONE, Vol 17, Iss 1, p e0261591 (2022)
PLoS ONE, Vol 17, Iss 1 (2022)
Objective To evaluate whether telomere length (TL), mitochondrial-DNA (mt-DNA) or epigenetic age estimators based on DNA methylation (DNAm) pattern could be considered reliable predictors of in-vitro-fertilization (IVF) success in terms of live birth
Autor:
L. Vernizzi, Christian F. Lehner
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 17, Iss 10, p e1009870 (2021)
PLoS Genetics, Vol 17, Iss 10, p e1009870 (2021)
Reduction of genome ploidy from diploid to haploid necessitates stable pairing of homologous chromosomes into bivalents before the start of the first meiotic division. Importantly, this chromosome pairing must avoid interlocking of non-homologous chr
Publikováno v:
PLoS Genetics
PLoS Genetics, Public Library of Science, 2021, 17 (7), pp.e1009700. ⟨10.1371/journal.pgen.1009700⟩
PLoS Genetics, Vol 17, Iss 7, p e1009700 (2021)
PLoS Genetics, Public Library of Science, 2021, 17 (7), pp.e1009700. ⟨10.1371/journal.pgen.1009700⟩
PLoS Genetics, Vol 17, Iss 7, p e1009700 (2021)
Accurate chromosome segregation during meiosis is essential for reproductive success. Yet, many fundamental aspects of meiosis remain unclear, including the mechanisms regulating homolog pairing across species. This gap is partially due to our inabil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0e7f3fdc8dbe01d6d453bed5405bbcf
https://hal.sorbonne-universite.fr/hal-03335909
https://hal.sorbonne-universite.fr/hal-03335909
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 7, p e0254138 (2021)
PLoS ONE, Vol 16, Iss 7, p e0254138 (2021)
Parasitic lice demonstrate an unusual array of mitochondrial genome architectures and gene arrangements. We characterized the mitochondrial genome of Geomydoecus aurei, a chewing louse (Phthiraptera: Trichodectidae) found on pocket gophers (Rodentia: