Výsledky vyhledávání - "Chromosomal aberrations and cancer"

A null mutation in the cystatin M/E gene of ichq mice causes juvenile lethality and defects in epidermal cornification

Autor: Wiljan Hendriks, Gerard Merkx, Joost Schalkwijk, Ivonne M.J.J. van Vlijmen-Willems, Patrick L.J.M. Zeeuwen

Publikováno v: Human Molecular Genetics, 11, 2867-75
Human Molecular Genetics, 11, 23, pp. 2867-75

Item does not contain fulltext Cystatin M/E (CST6 ), a new member of the cystatin gene family, has a restricted expression pattern in humans, which is largely limited to cutaneous epithelia. Although cystatin M/E possesses two distinct biochemical pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0fd182be0db439676d4f061d9248934
https://doi.org/10.1093/hmg/11.23.2867

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Limitations of cytokeratin 20 RT-PCR to detect disseminated tumour cells in blood and bone marrow of patients with colorectal cancer: expression in controls and downregulation in tumour tissue

Autor: C.J.A. Punt, Th. Wobbes, F.A. Vlems, G.N.P. van Muijen, M.J.L. Ligtenberg, J. H. S. Diepstra, Theo J.M. Ruers, I. M. H. A. Cornelissen, J.H.J.M. van Krieken

Publikováno v: Molecular Pathology, 55, 156-63
Molecular Pathology, 55, 3, pp. 156-63
Molecular pathology, 55(3), 156-163. BMJ Publishing Group

Contains fulltext : 173875.pdf (Publisher’s version ) (Closed access) AIMS: Despite informative staging of patients with colorectal cancer, some patients with localised disease at diagnosis will develop recurrence or metastasis. Attempts to improve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37a0fda9f19301958f3e44a4899ba254
https://doi.org/10.1136/mp.55.3.156

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[Perinatal asphyxia as incorrect explanation for mental retardation]

Autor: Tuerlings, J.H.A.M., Smits, A.P.T., Berg, P.P. van den

Publikováno v: Nederlands Tijdschrift voor Geneeskunde, 146, 1765-8
Nederlands Tijdschrift voor Geneeskunde, 146, 38, pp. 1765-8

Item does not contain fulltext Three women, aged 21, 34 and 32 and with a family history of mental retardation said to be caused by perinatal asphyxia, each gave birth to a child with mental retardation. A chromosomal translocation, fragile X syndrom

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::0816a0bb63787c39915e970f1dc328cf
https://hdl.handle.net/2066/165285

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A simple technique for high-throughput screening of drugs that modulate normal and psoriasis-like differentiation in cultured human keratinocytes

Autor: Rolph Pfundt, Arno Pol, Fred van Ruissen, Joost Schalkwijk, Mieke Bergers

Publikováno v: Skin Pharmacology and Applied Skin Physiology, 15, 252-61
Skin Pharmacology and Applied Skin Physiology, 15, 4, pp. 252-61

Established treatments for psoriasis act ei-ther on hyperproliferation, inflammation, aberrant epidermal differentiation or a combination of these aspects of the disease. Potential new drugs for treatment of psoriasis or other disorders with abnormal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fe1938d8e71d83841f261012b89736c
https://hdl.handle.net/2066/223512

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Genomic organization, chromosomal localization, and 5' upstream region of the human DC-STAMP gene

Autor: Franca C. Hartgers, B. van der Woning, Gosse Jan Adema, Maaike W. G. Looman, Carl G. Figdor, G.F.M. Merkx

Publikováno v: Immunogenetics, 53, 2, pp. 145--9
Immunogenetics, 53, 145--9
Immunogenetics, 53, 2, pp. 145-149
Immunogenetics, 53, 145-149. Springer-verlag

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https://hdl.handle.net/2066/27300

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Molecular cytogenetic definition of three distinct chromosome arm 14q deletion intervals in gastrointestinal stromal tumors

Autor: Eric F.P.M. Schoenmakers, R. Sciot, P. Dal Cin, Maria Debiec-Rychter, Patrick Pauwels, Anne Hagemeijer

Publikováno v: Genes, Chromosomes & Cancer, 32, 26-3-32
Genes, Chromosomes & Cancer, 32, 1, pp. 26-3-32

Item does not contain fulltext Gastrointestinal stromal tumors (GISTs) are mesenchymal neoplasms characterized by frequent chromosome arm 14q losses. In this study, the 14q changes in a series of 39 histologically and immunohistochemically confirmed

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https://doi.org/10.1002/gcc.1163

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Histopathologic findings in explanted heart tissue from patients with end-stage idiopathic dilated cardiomyopathy

Autor: Jochem M. D. Galama, Aggie H.M.M. Balk, Willem J. G. Melchers, Dirk J. Ruiter, Nicolaas de Jonge, Nicole De Leeuw

Publikováno v: Transplant International, 14, 299-306. Wiley-Blackwell Publishing Ltd
Transplant International, 14, 299--306
Transplant International, 14, 5, pp. 299--306

Item does not contain fulltext Explanted hearts were examined to determine whether specific histopathologic features are present in the myocardium of patients with end-stage idiopathic dilated cardiomyopathy (IDC). Extensive histopathologic examinati

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https://doi.org/10.1007/s001470100339

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Specific steps in aneuploidization correlate with loss of heterozygosity of 9p21, 17p13 and 18q21 in the progression of pre-malignant laryngeal lesions

Autor: Joris A. Veltman, Johannes J. Manni, Anton H. N. Hopman, Fredrik J. Bot, Ingrid van Weert, Frans C. S. Ramaekers, Michaela Aubele

Publikováno v: International Journal of Cancer, 91, 2, pp. 193--9
International Journal of Cancer, 91, 193--9
International Journal of Cancer, 91, 193-199. Wiley

Item does not contain fulltext Laryngeal squamous-cell carcinoma is often preceded by pre-malignant lesions. In this study, pre-malignant as well as malignant laryngeal lesions were analyzed using p53 immunohistochemistry and in situ hybridization fo

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https://doi.org/10.1002/1097-0215(200002)9999:9999<::aid-ijc1029>3.3.co

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In situ demonstration of phosphorylated c-jun and p38 MAP kinase in epidermal keratinocytes following ultraviolet B irradiation of human skin

Autor: Pfundt, R., Vlijmen-Willems, I.M.J.J. van, Bergers, A.M.G., Wingens, M., Cloin, W.A.H., Schalkwijk, J.

Publikováno v: Journal of Pathology, 193, 2, pp. 248--55
Journal of Pathology, 193, 248--55

Item does not contain fulltext Ultraviolet B (UVB) irradiation is known to induce activation of cellular stress response pathways in cultured cells or intact human skin, as demonstrated by phosphorylation of MAP kinase family members and up- or down-

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https://hdl.handle.net/2066/272537

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Short stature as the only presenting feature in a patient with an isodicentric (Y)(q11.23) and gonadoblastoma. A clinical and molecular cytogenetic study

Autor: M.A. de Vroede, R.A. Zewald, Richard J. Sinke, I. van Seumeren, Margreet G. E. M. Ausems, Brigitte H. W. Faas, Jacques C. Giltay

Publikováno v: European Journal of Pediatrics, 160, 3, pp. 154--8
European Journal of Pediatrics, 160, 154--8

Item does not contain fulltext A 13-year-old phenotypically female patient presented with short stature (height SDS -2.6), but without any Turner stigmata or other dysmorphic features. Chromosome analysis showed mosaicism for an isodicentric (idic) (

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https://doi.org/10.1007/s004310000683

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