Zobrazeno 1 - 10
of 2 651
pro vyhledávání: '"Chromosomal Rearrangements"'
Autor:
Kaushal Parikh, MD, Faye R. Harris, MS, Giannoula Karagouga, MS, Amy Schrandt, CRA, Jay Mandrekar, PhD, Sarah Johnson, MS, Alexa McCune, BS, Dorsay Sadeghian, MD, Debarshi Roy, PhD, Katarzyna Polonis, PhD, Athanasios Gaitatzes, MS, Aaron O. Bungum, BS, Eric S. Edell, MD, Mitesh J. Borad, MD, Tobias Peikert, MD, Farhad Kosari, PhD, John Cheville, MD, George Vasmatzis, PhD, Aaron S. Mansfield, MD
Publikováno v:
JTO Clinical and Research Reports, Vol 5, Iss 12, Pp 100692- (2024)
Introduction: The spatially complex nature of mesothelioma and interventions like pleurodesis, surgery, and radiation often complicate imaging-based assessment. Further, cell-free DNA (cfDNA) based monitoring strategies are inadequate for mesotheliom
Externí odkaz:
https://doaj.org/article/aa57a27ee45d48ffae93e50fd75eed69
Publikováno v:
Ecology and Evolution, Vol 14, Iss 10, Pp n/a-n/a (2024)
ABSTRACT Natural selection is known to favor specific gene combinations, thereby shaping the evolution of recombination rates, often through epistatic interactions. However, the dynamics of these interacting factors within natural populations remain
Externí odkaz:
https://doaj.org/article/abc36c3ab5c8425f8db1249756be4c01
Autor:
Dun Liu, Chuangqi Chen, Qianwen Huang, Yunqiao Dong, Liqing Xu, Mei Dong, Zhenghong Zhu, Li Huang, Fang Wang, Lijia Zhang, Xiqian Zhang, Fenghua Liu
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
ObjectiveComplex chromosome rearrangements (CCR) are rare structural abnormalities involving at least three breakpoints, categorized into three types based on their structure: type A (three-way rearrangements), type B (double two-way translocations),
Externí odkaz:
https://doaj.org/article/2543a512f4a04667a97b2706840669e6
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Cancer chimeric, or fusion, transcripts are thought to most frequently appear due to chromosomal aberrations that combine moieties of unrelated normal genes. When being expressed, this results in chimeric RNAs having upstream and downstream parts rel
Externí odkaz:
https://doaj.org/article/baead3a859174dd691a5185c268c0a25
Autor:
Qing Liu, Lyuhan Ye, Mingzhi Li, Ziwei Wang, Gui Xiong, Yushi Ye, Tieyao Tu, Trude Schwarzacher, John Seymour (Pat) Heslop-Harrison
Publikováno v:
BMC Plant Biology, Vol 23, Iss 1, Pp 1-11 (2023)
Abstract Background The BOP (Bambusoideae, Oryzoideae, and Pooideae) clade of the Poaceae has a common ancestor, with similarities to the genomes of rice, Oryza sativa (2n = 24; genome size 389 Mb) and Brachypodium, Brachypodium distachyon (2n = 10;
Externí odkaz:
https://doaj.org/article/ac76cc23eb004cf9aea4e0602a24457a
Autor:
Vanessa Isabel Batista de Morais, Juliane Vida Lemos de Oliveira, Alessio Alesci, Mara Cristina de Almeida, Roberto Ferreira Artoni
Publikováno v:
Biology, Vol 13, Iss 9, p 708 (2024)
Chromosomal polymorphism is a significant aspect of population genetics, influencing the adaptation and evolution of species. In Rineloricaria lanceolata, a Neotropical fish species, chromosomal polymorphism has been observed, yet the underlying mech
Externí odkaz:
https://doaj.org/article/cf99d548a9054d9c9d7780f0879cecc4
Publikováno v:
Genetics and Molecular Biology, Vol 46, Iss 3 suppl 1 (2024)
Abstract Contrary to predictions from classical hybrid sterility models of chromosomal speciation, some organisms display high rates of karyotype variation. Ctenomys are the current mammals with the greatest interspecific and intraspecific chromosoma
Externí odkaz:
https://doaj.org/article/ac68ccbd97d74e9eb3e3a939ed02face
Autor:
Pablo Villarreal, Samuel O'Donnell, Nicolas Agier, Felipe Muñoz-Guzman, Jose Benavides-Parra, Kami Urbina, Tomas A. Peña, Mark Solomon, Roberto F. Nespolo, Gilles Fischer, Cristian Varela, Francisco A. Cubillos
Publikováno v:
mSystems, Vol 9, Iss 1 (2024)
ABSTRACTEvaluating domestication signatures beyond model organisms is essential for a thorough understanding of the genotype-phenotype relationship in wild and human-related environments. Structural variations (SVs) can significantly impact phenotype
Externí odkaz:
https://doaj.org/article/5d0e55c2cb304d0ca70fbbb52bba6c72
Autor:
Christopher W. Benson, Matthew R. Sheltra, Peter J. Maughan, Eric N. Jellen, Matthew D. Robbins, B. Shaun Bushman, Eric L. Patterson, Nathan D. Hall, David R. Huff
Publikováno v:
BMC Genomics, Vol 24, Iss 1, Pp 1-20 (2023)
Abstract Background Poa annua (annual bluegrass) is an allotetraploid turfgrass, an agronomically significant weed, and one of the most widely dispersed plant species on earth. Here, we report the chromosome-scale genome assemblies of P. annua’s di
Externí odkaz:
https://doaj.org/article/02d06319eac444b5a907ae92de456e1a
Autor:
Alejandra Damián, Gonzalo Núñez-Moreno, Claire Jubin, Alejandra Tamayo, Marta Rodríguez de Alba, Cristina Villaverde, Cédric Fund, Marc Delépine, Aurélie Leduc, Jean François Deleuze, Pablo Mínguez, Carmen Ayuso, Marta Corton
Publikováno v:
Human Genomics, Vol 17, Iss 1, Pp 1-12 (2023)
Abstract Background Haploinsufficiency of the transcription factor PAX6 is the main cause of congenital aniridia, a genetic disorder characterized by iris and foveal hypoplasia. 11p13 microdeletions altering PAX6 or its downstream regulatory region (
Externí odkaz:
https://doaj.org/article/d7b6bf8c425a4fb8968b32b2ebc4f0c9