Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Chromobodies"'
Autor:
Malini Rajan, Oliver Mortusewicz, Ulrich Rothbauer, Florian D. Hastert, Katrin Schmidthals, Alexander Rapp, Heinrich Leonhardt, M. Cristina Cardoso
Publikováno v:
FEBS Open Bio, Vol 5, Iss 1, Pp 779-788 (2015)
Post‐translational modifications are difficult to visualize in living cells and are conveniently analyzed using antibodies. Single‐chain antibody fragments derived from alpacas and called nanobodies can be expressed and bind to the target antigen
Externí odkaz:
https://doaj.org/article/ba209d7079364f15884bd6637543f620
Under the Microscope: Single-Domain Antibodies for Live-Cell Imaging and Super-Resolution Microscopy
Autor:
Bjoern Traenkle, Ulrich Rothbauer
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Single-domain antibodies (sdAbs) have substantially expanded the possibilities of advanced cellular imaging such as live-cell or super-resolution microscopy to visualize cellular antigens and their dynamics. In addition to their unique properties inc
Externí odkaz:
https://doaj.org/article/b04f4c8ad7f14bf688223b10b37acf58
Autor:
Fagbadebo, Funmilayo Opeyemi
Mitochondrial outer membrane (MOM) associated proteins are critical players in mitochondrial transport, dynamics, and quality control. The MOM-anchored GTPase, Miro1, is a key player in mitochondrial transport, homeostasis and mitophagy. Aberrant Mir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______707::f3e24d0d34a9e17149f68eab5775ca91
https://hdl.handle.net/10900/129792
https://hdl.handle.net/10900/129792
Autor:
Bettina-Maria Keller, Julia Maier, Melissa Weldle, Soeren Segan, Bjoern Traenkle, Ulrich Rothbauer
Publikováno v:
Antibodies, Vol 8, Iss 1, p 10 (2019)
Single-domain antibodies have emerged as highly versatile nanoprobes for advanced cellular imaging. For real-time visualization of endogenous antigens, fluorescently labelled nanobodies (chromobodies, CBs) are introduced as DNA-encoded expression con
Externí odkaz:
https://doaj.org/article/091293d1e48a4f2f922c31b40070c5e2
Autor:
Ulrich Rothbauer, Melissa Weldle, Bettina-Maria Keller, Bjoern Traenkle, Soeren Segan, Julia Maier
Publikováno v:
Antibodies
Volume 8
Issue 1
Antibodies, Vol 8, Iss 1, p 10 (2019)
Volume 8
Issue 1
Antibodies, Vol 8, Iss 1, p 10 (2019)
Single-domain antibodies have emerged as highly versatile nanoprobes for advanced cellular imaging. For real-time visualization of endogenous antigens, fluorescently labelled nanobodies (chromobodies, CBs) are introduced as DNA-encoded expression con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efe1386411b369b5596b2f644b856812
Autor:
Heinrich Leonhardt, Florian D. Hastert, Katrin Schmidthals, M. Cristina Cardoso, Oliver Mortusewicz, Malini Rajan, Ulrich Rothbauer, Alexander Rapp
Publikováno v:
FEBS Open Bio
FEBS Open Bio, Vol 5, Iss 1, Pp 779-788 (2015)
FEBS Open Bio, Vol 5, Iss 1, Pp 779-788 (2015)
Highlights • An alpaca-derived γ-H2AX nanobody was generated. • γ-H2AX chromobody was able to bind and precipitate phosphorylated H2AX peptide. • γ-H2AX chromobody could be produced in bacterial as well as mammalian cells. • Alternative ep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1823e9dd3b045c07ad18c6c97ff6e71d
https://doi.org/10.1016/j.fob.2015.09.005
https://doi.org/10.1016/j.fob.2015.09.005
Under the Microscope: Single-Domain Antibodies for Live-Cell Imaging and Super-Resolution Microscopy
Autor:
Traenkle, Bjoern, Rothbauer, Ulrich
Publikováno v:
Frontiers in Immunology
Single-domain antibodies (sdAbs) have substantially expanded the possibilities of advanced cellular imaging such as live-cell or super-resolution microscopy to visualize cellular antigens and their dynamics. In addition to their unique properties inc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::ff56bf6bd3938c2bae6b23d3b3a9a5ab
http://europepmc.org/articles/PMC5573807
http://europepmc.org/articles/PMC5573807
Akademický článek
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Autor:
Julia Maier, Bjoern Traenkle, Ulrich Rothbauer, Kenji Schorpp, Ina Rothenaigner, Kamyar Hadian
Publikováno v:
J. Biomol. Screen. 21, 965-977 (2016)
Many screening hits show relatively poor quality regarding later efficacy and safety. Therefore, small-molecule screening efforts shift toward high-content analysis providing more detailed information. Here, we describe a novel screening approach to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5836dc221de43922404d47ce632251fc
https://pubmed.ncbi.nlm.nih.gov/27044685
https://pubmed.ncbi.nlm.nih.gov/27044685
Kniha
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