Zobrazeno 1 - 10
of 11 438
pro vyhledávání: '"Chromatin Structure"'
Autor:
Kevin Qiu, Duc C. Vu, Leran Wang, Nicholas N. Nguyen, Anna K. Bookstaver, Katia Sol-Church, Hui Li, Thang N. Dinh, Adam N. Goldfarb, Daniel G. Tenen, Bon Q. Trinh
Publikováno v:
Epigenetics & Chromatin, Vol 17, Iss 1, Pp 1-15 (2024)
Abstract The precise spatiotemporal expression of the hematopoietic ETS transcription factor PU.1, a key determinant of hematopoietic cell fates, is tightly regulated at the chromatin level. However, how chromatin signatures are linked to this dynami
Externí odkaz:
https://doaj.org/article/6da514938aad45c5a8aea53a79f08749
Autor:
Yue Xue, Lu Liu, Ye Zhang, Yueying He, Jingyao Wang, Zicheng Ma, Tie-jun Li, Jianyun Zhang, Yanyi Huang, Yi Qin Gao
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-24 (2024)
Abstract Epigenetic alterations, such as those in chromatin structure and DNA methylation, have been extensively studied in a number of tumor types. But oral cancer, particularly oral adenocarcinoma, has received far less attention. Here, we combined
Externí odkaz:
https://doaj.org/article/0da54a8280514b258033a8ee0a4224d3
Autor:
Janardan Khadka, Vikas S. Trishla, Sasank Sannidhi, Jeevan R. Singiri, Rohith Grandhi, Anat Pesok, Nurit Novoplansky, Zachor Adler-Agmon, Gideon Grafi
Publikováno v:
BMC Plant Biology, Vol 24, Iss 1, Pp 1-14 (2024)
Abstract The H2B.8 variant has been diverged from other variants by its extended N-terminal region that possesses a conserved domain. We generated transgenic Arabidopsis plants expressing H2B.9 (class I), H2B.5 (class II) and H2B.8 (class III) fused
Externí odkaz:
https://doaj.org/article/725ae05a665541139231dfee7f8b347c
Publikováno v:
Molecular Systems Biology, Vol 20, Iss 7, Pp 799-824 (2024)
Abstract Transcription factor (TF) residence on chromatin translates into quantitative transcriptional or structural outcomes on genome. Commonly used formaldehyde crosslinking fixes TF-DNA interactions cumulatively and compromises the measured occup
Externí odkaz:
https://doaj.org/article/ef9159d029ef4f10a05f703ec9f7e814
Autor:
Anurag Kumar Singh, Kaivalya Walavalkar, Daniele Tavernari, Giovanni Ciriello, Dimple Notani, Radhakrishnan Sabarinathan
Publikováno v:
Molecular Oncology, Vol 18, Iss 5, Pp 1189-1208 (2024)
Human papillomavirus (HPV) infections are the primary drivers of cervical cancers, and often HPV DNA gets integrated into the host genome. Although the oncogenic impact of HPV encoded genes is relatively well known, the cis‐regulatory effect of int
Externí odkaz:
https://doaj.org/article/01261b876af14c5ab98346a530512cef
Autor:
Masatoshi OOGA
Publikováno v:
The Journal of Reproduction and Development, Vol 70, Iss 3, Pp 152-159 (2024)
Totipotency refers to the ability of a single cell to give rise to all the different cell types in the body. Terminally differentiated germ cells (sperm and oocytes) undergo reprogramming, which results in the acquisition of totipotency in zygotes. S
Externí odkaz:
https://doaj.org/article/b79238bbfb314d58a446893ae436d6dd
Autor:
Xiaomin Li, Ci Ren, Anni Huang, Yue Zhao, Liming Wang, Hui Shen, Chun Gao, Bingxin Chen, Tong Zhu, Jinfeng Xiong, Da Zhu, Yafei Huang, Jianlin Ding, Zan Yuan, Wencheng Ding, Hui Wang
Publikováno v:
Journal of Advanced Research, Vol 57, Iss , Pp 163-180 (2024)
Introduction: Human papillomavirus (HPV) integration can induce gene expression dysregulation by destroying higher-order chromatin structure in cervical cancer. Objectives: We established a 13q22 site-specific HPV16 gene knock-in cell model to interr
Externí odkaz:
https://doaj.org/article/bfe4e7d81c1042e1843c177e64ab471b
Autor:
Xavier Devos, Jean-Bernard Fiche, Marion Bardou, Olivier Messina, Christophe Houbron, Julian Gurgo, Marie Schaeffer, Markus Götz, Thomas Walter, Florian Mueller, Marcelo Nollmann
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-11 (2024)
Abstract Genome-wide ensemble sequencing methods improved our understanding of chromatin organization in eukaryotes but lack the ability to capture single-cell heterogeneity and spatial organization. To overcome these limitations, new imaging-based m
Externí odkaz:
https://doaj.org/article/71e8100ef7ff4548802e158a94de3b06
Autor:
Yan Li, Wei Xu, Juan Wang, Hong Liu, Jiawen Liu, Liang Zhang, Rong Hou, Fujun Shen, Yuliang Liu, Kailai Cai
Publikováno v:
BMC Zoology, Vol 9, Iss 1, Pp 1-11 (2024)
Abstract Background Behaviors in captive animals, including changes in appetite, activity level, and social interaction, are often seen as adaptive responses. However, these behaviors may become progressively maladaptive, leading to stress, anxiety,
Externí odkaz:
https://doaj.org/article/890a8269195c4d679224899899e93c2e
Publikováno v:
Cells, Vol 13, Iss 22, p 1896 (2024)
Structural maintenance of chromosomes (SMC) complexes play a crucial role in organizing the three-dimensional structure of chromatin, facilitating key processes such as gene regulation, DNA repair, and chromosome segregation. This review explores the
Externí odkaz:
https://doaj.org/article/483467d64c4c4336af4a6e49e3b97160