Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Chromatin 3D architecture"'
Autor:
Tongtong Yan, Kexin Wang, Kexin Feng, Xiangchen Gao, Yinghong Jin, Hongping Wu, Wenfei Zhang, Li Wei
Publikováno v:
Biotechnology for Biofuels and Bioproducts, Vol 16, Iss 1, Pp 1-20 (2023)
Abstract Background Genomic three-dimensional (3D) spatial organization plays a key role in shaping gene expression and associated chromatin modification, and it is highly sensitive to environmental stress conditions. In microalgae, exposure to nitro
Externí odkaz:
https://doaj.org/article/ab9b511cf8c44b9e9f78a7509d37078a
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
V(D)J recombination is an essential mechanism of the adaptive immune system, producing a diverse set of antigen receptors in developing lymphocytes via regulated double strand DNA break and subsequent repair. DNA cleavage is initiated by the recombin
Externí odkaz:
https://doaj.org/article/a0c06117416c44109451e262c57a4970
Autor:
Feifei Li, Danyang Wang, Ruigao Song, Chunwei Cao, Zhihua Zhang, Yu Wang, Xiaoli Li, Jiaojiao Huang, Qiang Liu, Naipeng Hou, Bingxiang Xu, Xiao Li, Xiaomeng Gao, Yan Jia, Jianguo Zhao, Yanfang Wang
Publikováno v:
Genome Biology, Vol 21, Iss 1, Pp 1-21 (2020)
Abstract Background Pigs are important animals for agricultural and biomedical research, and improvement is needed for use of the assisted reproductive technologies. Determining underlying mechanisms of epigenetic reprogramming in the early stage of
Externí odkaz:
https://doaj.org/article/5025e0547df244ba92888983ebad2ef6
Autor:
Andres M. Cardozo Gizzi
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
The genome tridimensional (3D) organization and its role towards the regulation of key cell processes such as transcription is currently a main question in biology. Interphase chromosomes are spatially segregated into “territories,” epigeneticall
Externí odkaz:
https://doaj.org/article/af305b700cbb40f297ce41bae2185e13
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/06cc2c7b810d4abebd8e764b6e94f79c
Autor:
Michael Mariani, Cosima Zimmerman, Princess Rodriguez, Ellie Hasenohr, Giulia Aimola, Diana Lea Gerrard, Alyssa Richman, Andrea Dest, Louis Flamand, Benedikt Kaufer, Seth Frietze
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Human herpesvirus -6A and 6B (HHV-6A/B) can integrate their genomes into the telomeres of human chromosomes. Viral integration can occur in several cell types, including germinal cells, resulting in individuals that harbor the viral genome in every c
Externí odkaz:
https://doaj.org/article/d85cc2ce8d264931b40061c711a25213
Autor:
Yuki Fujita, Toshihide Yamashita
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2021)
Microglia are resident immune cells in the central nervous system (CNS). Microglia exhibit diversity in their morphology, density, electrophysiological properties, and gene expression profiles, and play various roles in neural development and adultho
Externí odkaz:
https://doaj.org/article/ae31bc5f619142928e74d827618959f9
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
The principles and function of chromatin and nuclear architecture have been extensively studied in model organisms, such as Drosophila melanogaster. However, little is known about the role of these epigenetic processes in transcriptional regulation i
Externí odkaz:
https://doaj.org/article/1f365763c4af49ada30f33c70b2a470e
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Genome organization plays a crucial role in gene regulation, orchestrating multiple cellular functions. A meshwork of proteins constituting a three-dimensional (3D) matrix helps in maintaining the genomic architecture. Sequences of DNA that are invol
Externí odkaz:
https://doaj.org/article/51668801fc704de3bcda5ff149827326
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
The hereditary anemias are a relatively heterogeneous set of disorders that can show wide clinical and genetic heterogeneity, which often hampers correct clinical diagnosis. The classical diagnostic workflow for these conditions generally used to sta
Externí odkaz:
https://doaj.org/article/4c8f86b655a5461a85c02bf4f292d220