Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Chritica Lodder"'
Autor:
Chritica Lodder, Isabelle Scheyltjens, Ilie Cosmin Stancu, Pablo Botella Lucena, Manuel Gutiérrez de Ravé, Sarah Vanherle, Tim Vanmierlo, Niels Cremers, Hannah Vanrusselt, Bert Brône, Bernard Hanseeuw, Jean-Noël Octave, Astrid Bottelbergs, Kiavash Movahedi, Ilse Dewachter
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-21 (2021)
Abstract Alzheimer's disease (AD) is characterized by a sequential progression of amyloid plaques (A), neurofibrillary tangles (T) and neurodegeneration (N), constituting ATN pathology. While microglia are considered key contributors to AD pathogenes
Externí odkaz:
https://doaj.org/article/852fe2a6f7d24a1d8306a8d889edd584
Autor:
Ilie Cosmin Stancu, Chritica Lodder, Pablo Botella Lucena, Sarah Vanherle, Manuel Gutiérrez de Ravé, Dick Terwel, Astrid Bottelbergs, Ilse Dewachter
Publikováno v:
Glia. 70:1117-1132
An active role of neuroinflammation and the NLRP3 inflammasome in Alzheimer's disease and related tauopathies is increasingly identified, supporting NLRP3 as an interesting therapeutic target. However, its effect on tau-associated neurodegeneration,
Autor:
Pablo Botella Lucena, Sarah Vanherle, Chritica Lodder, Manuel Gutiérrez de Ravé, Ilie-Cosmin Stancu, Ivo Lambrichts, Riet Vangheluwe, Rose Bruffaerts, Ilse Dewachter
Publikováno v:
Acta neuropathologica
Acta Neuropathologica
Acta Neuropathologica
Blood-based (BB) biomarkers for A beta and tau can indicate pathological processes in the brain, in the early pathological, even pre-symptomatic stages in Alzheimer's disease. However, the relation between BB biomarkers and AD-related processes in th
Autor:
Astrid Bottelbergs, Pablo Botella Lucena, Chritica Lodder, Bernard Hanseeuw, Niels Cremers, Hannah Vanrusselt, Tim Vanmierlo, Ilse Dewachter, Jean-Noël Octave, Isabelle Scheyltjens, Sarah Vanherle, Bert Brône, Manuel Gutiérrez de Ravé, Ilie-Cosmin Stancu, Kiavash Movahedi
Publikováno v:
Acta neuropathologica communications, Vol. 9, no. 1, p. 108 [1-21] (2021)
Acta Neuropathologica Communications
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-21 (2021)
Acta Neuropathologica Communications
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-21 (2021)
Alzheimer's disease (AD) is characterized by a sequential progression of amyloid plaques (A), neurofibrillary tangles (T) and neurodegeneration (N), constituting ATN pathology. While microglia are considered key contributors to AD pathogenesis, their
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0575ed9d7cfe6b821e4eb06ba21dec36
https://doi.org/10.1186/s40478-021-01204-8
https://doi.org/10.1186/s40478-021-01204-8
Autor:
François Huaux, Ilse Dewachter, Dick Terwel, Sofie Kessels, Chritica Lodder, Ilie-Cosmin Stancu, Niels Cremers, Hannah Vanrusselt, Alexandre Vanoosthuyse, Julien Couturier, Jean-Noël Octave, Bert Brône
Publikováno v:
Acta neuropathologica, Vol. 137, no. 4, p. 599-617 (2019)
Acta Neuropathologica
Acta Neuropathologica
Brains of Alzheimer’s disease patients are characterized by the presence of amyloid plaques and neurofbrillary tangles, both invariably associated with neuroinfammation. A crucial role for NLRP3–ASC infammasome [NACHT, LRR and PYD domains-contain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::826f360a579ddf1c4a08a444a4d2309d
https://hdl.handle.net/2078.1/214418
https://hdl.handle.net/2078.1/214418