Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Christy-Lynn M. Cooke"'
Autor:
Mazhar Pasha, Raven Kirschenman, Amy Wooldridge, Floor Spaans, Christy-Lynn M. Cooke, Sandra T. Davidge
Publikováno v:
PLoS ONE, Vol 18, Iss 4 (2023)
Advanced maternal age (≥35 years) is associated with an increased risk of pregnancy complications such as fetal growth restriction and preeclampsia. We previously demonstrated poor pregnancy outcomes (reduced fetal body weight), altered vascular fu
Externí odkaz:
https://doaj.org/article/dc7fcaa13bf14cd38dc514ba2b3c88fd
Autor:
Nataliia Hula, Ricky Liu, Floor Spaans, Mazhar Pasha, Anita Quon, Raven Kirschenman, Christy-Lynn M. Cooke, Sandra T. Davidge
Publikováno v:
Biomedicines, Vol 10, Iss 12, p 3019 (2022)
Prenatal hypoxia predisposes the offspring to the development of cardiovascular (CV) dysfunction in adult life. Using a rat model, we assessed the effect of prenatal hypoxia on vasoconstrictive and vasodilative mechanisms in left anterior descending
Externí odkaz:
https://doaj.org/article/b241108c56b44c53a1ffd6f7206aa001
Autor:
Amy L. Wooldridge, Mazhar Pasha, Palehswan Chitrakar, Raven Kirschenman, Anita Quon, Floor Spaans, Tamara Sáez, Christy-Lynn M. Cooke, Sandra T. Davidge
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 16, p 9191 (2022)
Advanced maternal age (≥35 years) is associated with pregnancy complications. Aging impairs vascular reactivity and increases vascular stiffness. We hypothesized that uterine artery adaptations to pregnancy are impaired with advanced age. Uterine a
Externí odkaz:
https://doaj.org/article/a3ab61a98dd6439b8d25d9e21564eda6
Autor:
Mazhar Pasha, Amy L. Wooldridge, Raven Kirschenman, Floor Spaans, Sandra T. Davidge, Christy-Lynn M. Cooke
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Advanced maternal age (≥35 years old) increases the risk of pregnancy complications such as preeclampsia and fetal growth restriction. We previously demonstrated vascular dysfunction and abnormal pregnancy outcomes in a rat model of advanced matern
Externí odkaz:
https://doaj.org/article/619045011eb84ec0ad3c246d1aca3ab1
Autor:
Mazhar Pasha, Raven Kirschenman, Amy Wooldridge, Floor Spaans, Christy-Lynn M. Cooke, Sandra T. Davidge
Publikováno v:
Antioxidants, Vol 11, Iss 7, p 1275 (2022)
Advanced maternal age (≥35 years) increases the risk of vascular complications in pregnancy that can result in fetal growth restriction and preeclampsia. Endoplasmic reticulum (ER) stress has been linked to adverse pregnancy outcomes in these compl
Externí odkaz:
https://doaj.org/article/24e94f51bafd453cb013b4093a203477
Autor:
Esha Ganguly, Mais M. Aljunaidy, Raven Kirschenman, Floor Spaans, Jude S. Morton, Thomas E. J. Phillips, C. Patrick Case, Christy-Lynn M. Cooke, Sandra T. Davidge
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
Pregnancy complications associated with chronic fetal hypoxia have been linked to the development of adult cardiovascular disease in the offspring. Prenatal hypoxia has been shown to increase placental oxidative stress and impair placental function i
Externí odkaz:
https://doaj.org/article/87788c841e1e430ab9314ed7060693a1
Autor:
Amy L. Wooldridge, Nataliia Hula, Raven Kirschenman, Floor Spaans, Christy-Lynn M. Cooke, Sandra T. Davidge
Publikováno v:
Journal of Developmental Origins of Health and Disease. 13:794-799
Prenatal hypoxia is a common complication of pregnancy and is associated with detrimental health outcomes, such as impaired cardiac and vascular function, in adult offspring. Exposure to prenatal hypoxia reportedly impacts the reproductive system of
Autor:
Nataliia Hula, Jennie Vu, Anita Quon, Raven Kirschenman, Floor Spaans, Ricky Liu, Christy-Lynn M. Cooke, Sandra T. Davidge
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 322:H442-H450
We demonstrated that prenatal hypoxia (a common condition of pregnancy) can have profound differential effects on treatment strategies in adult cardiovascular disease. Our data using a rat model of prenatal hypoxia demonstrated that, as adults, altho
Autor:
Roberto Villalobos-Labra, Ricky Liu, Floor Spaans, Tamara Sáez, Anita Quon, Michael Wong, Desmond Pink, John Lewis, Manu Vatish, Sandra T. Davidge, Christy-Lynn M. Cooke
Publikováno v:
Bioscience reports. 42(12)
Preeclampsia (PE) is a pregnancy syndrome characterized by new-onset hypertension and end-organ dysfunction. The pathophysiology of PE remains undetermined, but it is thought that maternal vascular dysfunction plays a central role, potentially due, i
Autor:
Amy L. Wooldridge, Mazhar Pasha, Palehswan Chitrakar, Raven Kirschenman, Floor Spaans, Christy‐Lynn M. Cooke, Sandra T. Davidge
Publikováno v:
The FASEB Journal. 36