Výsledky vyhledávání - "Christy Xavier"

Akademický článek

The novel triterpenoid RTA 408 protects human retinal pigment epithelial cells against H2O2-induced cell injury via NF-E2-related factor 2 (Nrf2) activation

Autor: Xiaobin Liu, Keith Ward, Christy Xavier, Jamieson Jann, Abbot F. Clark, Iok-Hou Pang, Hongli Wu

Publikováno v: Redox Biology, Vol 8, Iss C, Pp 98-109 (2016)

Oxidative stress-induced retinal pigment epithelial (RPE) cell damage is an important factor in the pathogenesis of age-related macular degeneration (AMD). Previous studies have shown that RTA 408, a synthetic triterpenoid compound, potently activate

Externí odkaz: https://doaj.org/article/1c0f93f6320e42dabc7b56db70e2761a

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Health Disparities of Coronavirus Disease 2019 in Texas, March–July 2020

Autor: Rafia S. Rasu, Christy Xavier

Publikováno v: Southern Medical Journal

Despite the fact that the disparity in the prevalence of coronavirus disease 2019 (COVID-19) is well known, knowledge about the recent surge of COVID-19 in Texas and factors affecting fatality rate is limited. Clinicians and decision makers should be

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6766c6f34b169e1f36fef4a20a02e33b
https://doi.org/10.14423/smj.0000000000001308

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Cost of Traditional Herbal Medicines for Noncommunicable Diseases in Rural and Urban Communities in South Africa

Autor: Gail D Hughes, Rafia S. Rasu, Bobby L. Clark, Oluwaseyi M. Aboyade, Osaretin Christabel Okonji, Christy Xavier, Walter Agbor Bawa

Publikováno v: Value in health regional issues. 29

This study assessed traditional herbal medicine (THM) and conventional medicine (CM) utilization among participants with noncommunicable disease in South Africa.A cross-sectional study of the Prospective Urban and Rural Epidemiological study collecte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbac2b95e8ef6cb0311f1cc9498bb868
https://pubmed.ncbi.nlm.nih.gov/34839077

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Involvement of Nrf2 in Ocular Diseases

Autor: Shehzad Y. Batliwala, Hongli Wu, Christy Xavier, Yang Liu, Iok-Hou Pang

Publikováno v: Oxidative Medicine and Cellular Longevity, Vol 2017 (2017)
Oxidative Medicine and Cellular Longevity

The human body harbors within it an intricate and delicate balance between oxidants and antioxidants. Any disruption in this checks-and-balances system can lead to harmful consequences in various organs and tissues, such as the eye. This review focus

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8fb52e712bd2c3e05d51819675eb869
https://doi.org/10.1155/2017/1703810

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PIN124 Analysis of Race and Ethnicity of COVID-19 Deaths in the United States

Autor: Rafia S. Rasu, Christy Xavier

Publikováno v: Value in Health

Objectives: Coronavirus Disease 2019 (COVID-19) is an ongoing pandemic in certain populations and regions in the United States Understanding the health disparities associated with COVID-19 deaths can help determine the populations in most need of COV

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e060455f77b13dcb4c6dbf79d6383428
https://doi.org/10.1016/j.jval.2020.08.965

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The novel triterpenoid RTA 408 protects human retinal pigment epithelial cells against H2O2-induced cell injury via NF-E2-related factor 2 (Nrf2) activation

Autor: Jamieson Jann, Iok-Hou Pang, Hongli Wu, Christy Xavier, Keith W. Ward, Abbot F. Clark, Xiaobin Liu

Publikováno v: Redox Biology, Vol 8, Iss C, Pp 98-109 (2016)
Redox Biology

Graphical abstract
Oxidative stress-induced retinal pigment epithelial (RPE) cell damage is an important factor in the pathogenesis of age-related macular degeneration (AMD). Previous studies have shown that RTA 408, a synthetic triterpenoid com

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e222fbd5018d0f4ab1fced9e19b7f7d
https://doi.org/10.1016/j.redox.2015.12.005

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Salvianolic Acid B (Sal B) Protects Retinal Pigment Epithelial Cells from Oxidative Stress-Induced Cell Death by Activating Glutaredoxin 1 (Grx1)

Autor: Jamieson Jann, Hongli Wu, Xiaobin Liu, Christy Xavier

Publikováno v: International Journal of Molecular Sciences, Vol 17, Iss 11, p 1835 (2016)
International Journal of Molecular Sciences; Volume 17; Issue 11; Pages: 1835
International Journal of Molecular Sciences

Protein glutathionylation, defined as the formation of protein mixed disulfides (PSSG) between cysteine residues and glutathione (GSH), can lead to cell death. Glutaredoxin 1 (Grx1) is a thiol repair enzyme which catalyzes the reduction of PSSG. Ther

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f9f01c4069284f39cdcf91c53f82d76
http://www.mdpi.com/1422-0067/17/11/1835

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Glutaredoxin 1 (Grx1) Protects Human Retinal Pigment Epithelial Cells From Oxidative Damage by Preventing AKT Glutathionylation

Autor: Xiaobin Liu, Jamieson Jann, Christy Xavier, Hongli Wu

Publikováno v: Investigative ophthalmologyvisual science. 56(5)

Purpose Glutaredoxin 1 (Grx1) belongs to the oxidoreductase family and is a component of the endogenous antioxidant defense system. However, its physiological function remains largely unknown. In this study, we investigated whether and how Grx1 overe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb2d6d1b7adbbec04c471bea5ab11cb0
https://pubmed.ncbi.nlm.nih.gov/25788646

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