The novel triterpenoid RTA 408 protects human retinal pigment epithelial cells against H2O2-induced cell injury via NF-E2-related factor 2 (Nrf2) activation

Autor: Xiaobin Liu, Keith Ward, Christy Xavier, Jamieson Jann, Abbot F. Clark, Iok-Hou Pang, Hongli Wu

Publikováno v: Redox Biology, Vol 8, Iss C, Pp 98-109 (2016)

Oxidative stress-induced retinal pigment epithelial (RPE) cell damage is an important factor in the pathogenesis of age-related macular degeneration (AMD). Previous studies have shown that RTA 408, a synthetic triterpenoid compound, potently activate

Externí odkaz: https://doaj.org/article/1c0f93f6320e42dabc7b56db70e2761a

Cost of Traditional Herbal Medicines for Noncommunicable Diseases in Rural and Urban Communities in South Africa

Autor: Gail D Hughes, Rafia S. Rasu, Bobby L. Clark, Oluwaseyi M. Aboyade, Osaretin Christabel Okonji, Christy Xavier, Walter Agbor Bawa

Publikováno v: Value in health regional issues. 29

This study assessed traditional herbal medicine (THM) and conventional medicine (CM) utilization among participants with noncommunicable disease in South Africa.A cross-sectional study of the Prospective Urban and Rural Epidemiological study collecte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbac2b95e8ef6cb0311f1cc9498bb868
https://pubmed.ncbi.nlm.nih.gov/34839077

PIN124 Analysis of Race and Ethnicity of COVID-19 Deaths in the United States

Autor: Rafia S. Rasu, Christy Xavier

Publikováno v: Value in Health

Objectives: Coronavirus Disease 2019 (COVID-19) is an ongoing pandemic in certain populations and regions in the United States Understanding the health disparities associated with COVID-19 deaths can help determine the populations in most need of COV

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e060455f77b13dcb4c6dbf79d6383428
https://doi.org/10.1016/j.jval.2020.08.965

Salvianolic Acid B (Sal B) Protects Retinal Pigment Epithelial Cells from Oxidative Stress-Induced Cell Death by Activating Glutaredoxin 1 (Grx1)

Autor: Jamieson Jann, Hongli Wu, Xiaobin Liu, Christy Xavier

Publikováno v: International Journal of Molecular Sciences, Vol 17, Iss 11, p 1835 (2016)
International Journal of Molecular Sciences; Volume 17; Issue 11; Pages: 1835
International Journal of Molecular Sciences

Protein glutathionylation, defined as the formation of protein mixed disulfides (PSSG) between cysteine residues and glutathione (GSH), can lead to cell death. Glutaredoxin 1 (Grx1) is a thiol repair enzyme which catalyzes the reduction of PSSG. Ther

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f9f01c4069284f39cdcf91c53f82d76
http://www.mdpi.com/1422-0067/17/11/1835

Salvianolic Acid B (Sal B) Protects Retinal Pigment Epithelial Cells from Oxidative Stress-Induced Cell Death by Activating Glutaredoxin 1 (Grx1).

Autor: Xiaobin Liu¹ xiaobin.liu@unthsc.edu, Xavier, Christy¹ Christy.Xavier@unthsc.edu, Jann, Jamieson¹ jjann@uga.edu, Hongli Wu^1,2 hongli.wu@unthsc.edu

Publikováno v: International Journal of Molecular Sciences. Nov2016, Vol. 17 Issue 11, p1835. 15p. 1 Diagram, 7 Graphs.