Výsledky vyhledávání - "Christy M. Wilson"

Quinic acid derivative KZ-41 exhibits radiomitigating activity in preclinical models of radiation injury

Autor: Karin E, Thompson, Kui, Zeng, Christy M, Wilson, Mostafa W, Gaber, Duane D, Miller, Charles R, Yates

Publikováno v: Drug development research. 75(1)

Acute radiation syndrome is induced when a significant portion of the body receives high-dose, as well as high-dose rate, radiation. We have previously identified a quinic acid-based derivative, KZ-41, that protects from radiation injury. Further pre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0c747130e522f91884eb7666664fc319
https://pubmed.ncbi.nlm.nih.gov/24648047

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Effects of irradiation on brain vasculature using an in situ tumor model

Autor: Thomas E. Merchant, Janice A. Zawaski, Christy M. Wilson, M. Waleed Gaber, Omaima M. Sabek, Christopher Duntsch

Publikováno v: International journal of radiation oncology, biology, physics. 82(3)

Purpose Damage to normal tissue is a limiting factor in clinical radiotherapy (RT). We tested the hypothesis that the presence of tumor alters the response of normal tissues to irradiation using a rat in situ brain tumor model. Methods and Materials

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::002902a66a6e5916577b915ceaee52b2
https://pubmed.ncbi.nlm.nih.gov/22197233

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Radiation-induced astrogliosis and blood-brain barrier damage can be abrogated using anti-TNF treatment

Autor: Omaima M. Sabek, M. Waleed Gaber, Thomas E. Merchant, Janice A. Zawaski, Christy M. Wilson

Publikováno v: International journal of radiation oncology, biology, physics. 74(3)

Purpose In this article, we investigate the role of tumor necrosis factor-alpha (TNF) in the initiation of acute damage to the blood-brain barrier (BBB) and brain tissue following radiotherapy (RT) for CNS tumors. Methods and Materials Intravital mic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d050aaadfe9b7bae706d4e089a1f8d4
https://pubmed.ncbi.nlm.nih.gov/19480972

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Effects of fractionated radiation on the brain vasculature in a murine model: blood-brain barrier permeability, astrocyte proliferation, and ultrastructural changes

Autor: Christy M. Wilson, Hong Yuan, M. Waleed Gaber, Kelli L. Boyd, Mohammad F. Kiani, Thomas E. Merchant

Publikováno v: International journal of radiation oncology, biology, physics. 66(3)

Purpose: Radiation therapy of CNS tumors damages the blood–brain barrier (BBB) and normal brain tissue. Our aims were to characterize the short- and long-term effects of fractionated radiotherapy (FRT) on cerebral microvasculature in mice and to in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8363f951dee7569970f5311ba37e5082
https://pubmed.ncbi.nlm.nih.gov/17011458

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Volumetric analysis of tumors in rodents using the variable resolution x-ray (VRX) CT-scanner

Autor: Christopher Duntsch, Frank A. DiBianca, Lawrence M. Jordan, Christy M. Wilson, Sravanthi Vangalaa, Gary S. Keyes, M. Waleed Gaber, David A. Rendon, Janice A. Zawaski, Hemant Shukla

Publikováno v: SPIE Proceedings.

The Variable Resolution X-ray (VRX) CT system, developed at the UTHSC, Memphis, has the potential for use in animal imaging. Animal models of tumor progression and pharmacological impact are becoming increasingly important in understanding the molecu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a4291ac2a2c2a336c8c963f15759983a
https://doi.org/10.1117/12.595786

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