Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Christy L. Frankowski-McGregor"'
Autor:
Cara Abecunas, Christopher E. Whitehead, Elizabeth K. Ziemke, Douglas G. Baumann, Christy L. Frankowski-McGregor, Judith S. Sebolt-Leopold, Mohammad Fallahi-Sichani
Publikováno v:
Cancer Research. 83:316-331
Neurofibromin 1 (NF1) loss of function (LoF) mutations are frequent in melanoma and drive hyperactivated RAS and tumor growth. NF1LoF melanoma cells, however, do not show consistent sensitivity to individual MEK, ERK, or PI3K/mTOR inhibitors. To iden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6781e4ee9244fb69c2ce7f5d534bf7ec
https://doi.org/10.1158/0008-5472.can-22-0883
https://doi.org/10.1158/0008-5472.can-22-0883
Autor:
Judith S. Sebolt-Leopold, Diane M. Simeone, Armand Bankhead, Christy L. Frankowski-McGregor, Joel D. Maust
Effects of trametinib and palbociclib alone and in combination on growth and expression of various signaling proteins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05e0b7dbc35bc11261055c3a23dbbf82
https://doi.org/10.1158/1535-7163.22510138.v1
https://doi.org/10.1158/1535-7163.22510138.v1
Autor:
Judith S. Sebolt-Leopold, Diane M. Simeone, Armand Bankhead, Christy L. Frankowski-McGregor, Joel D. Maust
COX-2 expression at the RNA and protein levels
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8d0ad061a798e76eca6dca39f94868c
https://doi.org/10.1158/1535-7163.22510135.v1
https://doi.org/10.1158/1535-7163.22510135.v1
Autor:
Judith S. Sebolt-Leopold, Diane M. Simeone, Armand Bankhead, Christy L. Frankowski-McGregor, Joel D. Maust
Effect of combination treatment on COX-2 and Pdcd4 expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ed86789034e499989e4b2f6eb558b26
https://doi.org/10.1158/1535-7163.22510141
https://doi.org/10.1158/1535-7163.22510141
Autor:
Judith S. Sebolt-Leopold, Diane M. Simeone, Armand Bankhead, Christy L. Frankowski-McGregor, Joel D. Maust
Impact of drug concentration and kinase inhibitor selection on synergistic response (L3.6pl model)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f31e773aa87e4695efe02f98a68c7c9
https://doi.org/10.1158/1535-7163.22510150.v1
https://doi.org/10.1158/1535-7163.22510150.v1
Autor:
Judith S. Sebolt-Leopold, Diane M. Simeone, Armand Bankhead, Christy L. Frankowski-McGregor, Joel D. Maust
Effect of combination treatment on growth and protein expression in models eliciting high and low synergy scores
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::161e13f2bf8136effcae3e59b55048f9
https://doi.org/10.1158/1535-7163.22510147
https://doi.org/10.1158/1535-7163.22510147
Autor:
Judith S. Sebolt-Leopold, Diane M. Simeone, Armand Bankhead, Christy L. Frankowski-McGregor, Joel D. Maust
Evaluation of in vivo efficacy to the combination of trametinib and palbociclib in L3.6pl tumor-bearing animals
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::214c120d537aef28eeef58d89d6bd77c
https://doi.org/10.1158/1535-7163.22510144.v1
https://doi.org/10.1158/1535-7163.22510144.v1
Autor:
Judith S. Sebolt-Leopold, Diane M. Simeone, Armand Bankhead, Christy L. Frankowski-McGregor, Joel D. Maust
The ineffectiveness of chemotherapy in patients with pancreatic cancer highlights a critical unmet need in pancreatic cancer therapy. Two commonly mutated genes in pancreatic cancer, KRAS and CDKN2A, have an incidence exceeding 90%, supporting invest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d4b662e30eb9098e047cb4a906ab2a5
https://doi.org/10.1158/1535-7163.c.6539521
https://doi.org/10.1158/1535-7163.c.6539521
Autor:
Mohammad Fallahi-Sichani, Judith S. Sebolt-Leopold, Christy L. Frankowski-McGregor, Douglas G. Baumann, Elizabeth K. Ziemke, Christopher E. Whitehead, Cara Abecunas
Supplementary Dataset S5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9545be3427b76ce3a0c8de4dcc9901de
https://doi.org/10.1158/0008-5472.22432743.v1
https://doi.org/10.1158/0008-5472.22432743.v1
Autor:
Mohammad Fallahi-Sichani, Judith S. Sebolt-Leopold, Christy L. Frankowski-McGregor, Douglas G. Baumann, Elizabeth K. Ziemke, Christopher E. Whitehead, Cara Abecunas
Supplementary Dataset Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75d8769aed5c7229d2e4598daa645aa8
https://doi.org/10.1158/0008-5472.22432758.v1
https://doi.org/10.1158/0008-5472.22432758.v1