Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Christy Jurgens"'
Autor:
Ross W. B. Lindsay, Ivo C. Lorenz, Jaap Willem Back, Gavin Morrow, Christy Jurgens, Sanjay Phogat, Hanh T. Nguyen, Joanne DeStefano, Heather Arendt, Christopher L. Parks, Kevin J. Wright, Maoli Yuan, M Kemelman, Simon Hoffenberg, Timothy J. Zamb
Publikováno v:
AIDS Research and Human Retroviruses. 30:1130-1144
The structure of the HIV-1 envelope membrane-proximal external region (MPER) is influenced by its association with the lipid bilayer on the surface of virus particles and infected cells. To develop a replicating vaccine vector displaying MPER sequenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9e9c57711f3b67f8f0fa9361e0d546f
https://doi.org/10.1089/aid.2013.0206
https://doi.org/10.1089/aid.2013.0206
Autor:
Maria J. Chiuchiolo, Rebecca L.R. Powell, Gavin Morrow, A Ouattara, M Kemelman, Arban Domi, Christopher L. Parks, Michael J. Caulfield, John W. Coleman, Christy Jurgens, Maoli Yuan, M Panis, N Tamot, Martin Backer, Mary Lopez, CR King, Kevin J. Wright, S Iyer, Cesar Boggiano
Publikováno v:
Retrovirology, Vol 9, Iss Suppl 2, p P329 (2012)
Retrovirology
Retrovirology
Background Immunity elicited by live attenuated vaccines confers protection against viral pathogens causing measles, yellow fever, smallpox and others, but this approach is not well suited to HIV vaccine development. Accordingly, to develop a vaccine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f7c9011d5b7b25426e15023c9b3bd61
https://doaj.org/article/00b3484a54c84ca8b7439832c32d1bd4
https://doaj.org/article/00b3484a54c84ca8b7439832c32d1bd4
Autor:
Perry J. Tiberio, CR King, Christopher L. Parks, Michael J. Caulfield, Aaron J. Wilson, M Kemelman, Sanjay Phogat, Christy Jurgens, Maoli Yuan, Kevin J. Wright, Simon Hoffenberg, Ivo C. Lorenz, Cesar Boggiano
Publikováno v:
Retrovirology
Methods Using a combination of nucleotide sequence optimization and protein domain swapping, we have generated a panel of novel gene inserts for VSV vectors that encode chimeric HIV-1 and VSV glycoprotein immunogens (EnvG). A stable VERO cell line en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c90eaa380539c14796d3d80646e58035
https://doi.org/10.1186/1742-4690-9-s2-p342
https://doi.org/10.1186/1742-4690-9-s2-p342
Autor:
Christy Jurgens, M Panis, Christopher L. Parks, Michael J. Caulfield, Ryan D. King, Aaron J. Wilson, Ivo C. Lorenz, Maria J. Chiuchiolo, Maoli Yuan, M Kemelman
Publikováno v:
Retrovirology, Vol 9, Iss Suppl 2, p P327 (2012)
Retrovirology
Retrovirology
Background The HIV-neutralizing activity of monoclonal antibodies 2F5, 4E10, and Z13 have shown that the membrane-proximal external region (MPER) of HIV Env is an important vaccine target, but development of an immunogen that elicits similar virus-ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40ffa5340511c8351449badae58f57b5
https://doaj.org/article/b13b240be9f3461bbf383bc00188b669
https://doaj.org/article/b13b240be9f3461bbf383bc00188b669
Autor:
Martha Collier, Robert E. Johnston, Ande West, Chad Cecil, Ronald Swanstrom, Alan C. Whitmore, Nancy L. Davis, Dominic T. Moore, Victoria J. Madden, Christy Jurgens
Venezuelan equine encephalitis virus replicon particles (VRP) were engineered to express different forms of SIV Gag to compare expression in vitro, formation of intra- and extracellular structures and induction of humoral and cellular immunity in mic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29ac4b99a94176d238feae94cc865b90
Autor:
Wayne C. Koff, CR King, M Kemelman, Aaron J. Wilson, Gavin Morrow, Rebecca L.R. Powell, Christy Jurgens, MG Delboy, Maoli Yuan, Perry J. Tiberio, Svetlana Rabinovich, Ivo C. Lorenz, Simon Hoffenberg, Kevin J. Wright, Maria J. Chiuchiolo, Christopher L. Parks, Xinsheng Zhang, Michael J. Caulfield, Cesar Boggiano, Ross W. B. Lindsay
Publikováno v:
Retrovirology
Retrovirology, Vol 9, Iss Suppl 2, p P341 (2012)
Retrovirology, Vol 9, Iss Suppl 2, p P341 (2012)
Methods We are using vesicular stomatitis virus (VSV) as a vector platform for delivery of Env immunogens as transmembrane glycoproteins. We have investigated a variety of vector designs and Env modifications to identify combinations that balance the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::728dffbf8dfe4428211f7d00d0e580af
http://europepmc.org/articles/PMC3441608
http://europepmc.org/articles/PMC3441608