Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Christy Hsu"'
Autor:
Yifeng Xia, Xiaodong Ji, In Sock Jang, Christine Surka, Christy Hsu, Kai Wang, Mark Rolfe, Neil Bence, Gang Lu
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-7 (2021)
Xia et al. report the development and optimization of a high-throughput screening platform to systematically determine cancer cell sensitivity to pharmacological and genetic perturbations, BMS-PRISM, based on PRISM and high-throughput CRISPR/Cas9 los
Externí odkaz:
https://doaj.org/article/4d8d29c70bdc4a77a7632fc27bcf2dfd
Autor:
Christy Hsu, In Sock Jang, Kai Wang, Gang Lu, Neil Bence, Christine Surka, Yifeng Xia, Mark Rolfe, Xiaodong Ji
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-7 (2021)
Communications Biology
Communications Biology
The multiplexed cancer cell line screening platform PRISM demonstrated its utility in testing hundreds of cell lines in a single run, possessing the potential to speed up anti-cancer drug discovery, validation and optimization. Here we described the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9368448a5200398e37c99198f8b38226
https://doaj.org/article/4d8d29c70bdc4a77a7632fc27bcf2dfd
https://doaj.org/article/4d8d29c70bdc4a77a7632fc27bcf2dfd
Autor:
Joshua Hansen, John E. Dick, Philip P Chamberlain, Emily Rychak, Gang Lu, In Sock Jang, Jean C.Y. Wang, Thomas Clayton, Celia Fontanillo, Derek Mendy, Michael Pourdehnad, Jinhong Fan, Stanley W.K. Ng, Eileen Tran, Mark Rolfe, Nathan Mbong, Kai Wang, Chin-Chun Lu, James Carmichael, Christine Surka, Mary E Matyskiela, Daniel W. Pierce, Mark D. Minden, Liqing Jin, Antonia Lopez-Girona, Brian E. Cathers, Elizabeth Anne Tindall, Adrian Contreras, Christy Hsu
Publikováno v:
Blood. 137:661-677
A number of clinically validated drugs have been developed by repurposing the CUL4-DDB1-CRBN-RBX1 (CRL4CRBN) E3 ubiquitin ligase complex with molecular glue degraders to eliminate disease-driving proteins. Here, we present the identification of a fir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::390854bdb0e3f67bbd5f3627b5b5ffe5
https://doi.org/10.1182/blood.2020008676
https://doi.org/10.1182/blood.2020008676