Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Christy A Comeaux"'
Autor:
Ann R. Falsey, Kristi Williams, Efi Gymnopoulou, Stephan Bart, John Ervin, Arangassery R. Bastian, Joris Menten, Els De Paepe, Sjouke Vandenberghe, Eric K.H. Chan, Jerald Sadoff, Macaya Douoguih, Benoit Callendret, Christy A. Comeaux, Esther Heijnen
Publikováno v:
New England Journal of Medicine. 388:609-620
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b1bf58720dcf2e3826f11d3a8fdc85ce
https://doi.org/10.1056/nejmoa2207566
https://doi.org/10.1056/nejmoa2207566
Autor:
Christy A Comeaux, Ann R Falsey, Kristi Williams, Stephan Bart, John E Ervin, Arangassery R Bastian, Joris Menten, Els De Paepe, Sjouke Vandenberghe, Eric K H Chan, Jerald Sadoff, Macaya Douoguih, Benoit Callendret, Esther Heijnen
Publikováno v:
Open Forum Infectious Diseases. 9
Background Respiratory syncytial virus (RSV) can cause serious lower respiratory tract disease (LRTD) among older adults. There is no licensed RSV vaccine. In CYPRESS (a randomized, double-blind, placebo-controlled, phase 2b proof-of concept trial; N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b4d88135bde6bb50c077017125381d8b
https://doi.org/10.1093/ofid/ofac492.152
https://doi.org/10.1093/ofid/ofac492.152
Publikováno v:
Molecular Microbiology. 80:378-390
The Plasmodium RhopH complex is a high molecular weight antigenic complex consisting of three subunits - RhopH1/clag, RhopH2 and RhopH3 - located in the rhoptry secretory organelles of the invasive merozoite. In Plasmodium falciparum RhopH1/clag is e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0cc327cce0a7c249b985a27335eba648
https://doi.org/10.1111/j.1365-2958.2011.07572.x
https://doi.org/10.1111/j.1365-2958.2011.07572.x
Autor:
Janine Stubbs, Alan F. Cowman, Tony Triglia, Manoj T. Duraisingh, Cameron V. Jennings, Tiffany M. DeSimone, Christy A. Comeaux, Amy K. Bei, Philippe Refour, Bradley I. Coleman
Publikováno v:
Molecular Microbiology. 72:578-589
Plasmodium falciparum is the most virulent of the Plasmodium species infective to humans. Different P. falciparum strains vary in their dependence on erythrocyte receptors for invasion and their ability to switch in their utilization of different rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4156361f3678b6f198367ad794efec21
https://doi.org/10.1111/j.1365-2958.2009.06667.x
https://doi.org/10.1111/j.1365-2958.2009.06667.x
Publikováno v:
Molecular and Biochemical Parasitology. 157:117-126
The complex life cycles of many protozoan parasites require the ability to respond to environmental and developmental cues through regulated gene expression. Traditionally, parasitologists have investigated these mechanisms by identifying and charact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::feae764fcfe4ead78a7f37b8d1f5d394
https://doi.org/10.1016/j.molbiopara.2007.10.004
https://doi.org/10.1016/j.molbiopara.2007.10.004
Autor:
Hidde L. Ploegh, Manoj T. Duraisingh, Shahram Misaghi, Eric Spooner, Katerina Artavanis-Tsakonas, Christy A. Comeaux, Andre Catic
Publikováno v:
Molecular Microbiology
Summary Ubiquitination is a post‐translational modification implicated in a variety of cellular functions, including transcriptional regulation, protein degradation and membrane protein trafficking. Ubiquitin and the enzymes that act on it, althoug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7abd35f585a11d507e6a16e63016f1c9
https://doi.org/10.1111/j.1365-2958.2006.05307.x
https://doi.org/10.1111/j.1365-2958.2006.05307.x
Publikováno v:
Developmental Biology. 287(1):19-34
Positioning an organ with respect to other tissues is a complex process necessary for proper anatomical development and organ function. The local environment surrounding an organ can serve both as a substrate for migration and as a source of guidance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc276f6ac186500f60f9d0c4f91f5567
Publikováno v:
Molecular microbiology. 80(2)
The Plasmodium RhopH complex is a high molecular weight antigenic complex consisting of three subunits – RhopH1/clag, RhopH2 and RhopH3 – located in the rhoptry secretory organelles of the invasive merozoite. In Plasmodium falciparum RhopH1/clag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e57f6ed99ffce4182c589c69a1447990
https://pubmed.ncbi.nlm.nih.gov/21320181
https://pubmed.ncbi.nlm.nih.gov/21320181
Autor:
Hidde L. Ploegh, Manoj T. Duraisingh, Bradley I. Coleman, Rachelle Gaudet, Wilhelm A. Weihofen, John M. Antos, Katerina Artavanis-Tsakonas, Christy A. Comeaux
Like their human hosts, Plasmodium falciparum parasites rely on the ubiquitin-proteasome system for survival. We previously identified PfUCHL3, a deubiquitinating enzyme, and here we characterize its activity and changes in active site architecture u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0f7d8e54769726ef0da84f49af37008
https://europepmc.org/articles/PMC2825479/
https://europepmc.org/articles/PMC2825479/
Publikováno v:
Molecular Microbiology. :071120025032003
Summary Epigenetic phenomena have been shown to play a role in the regulated expression of virulence genes in several pathogenic organisms, including the var gene family in Plasmodium falciparum. A better understanding of how P. falciparum can both m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e43761eabce509c9d0f6789448e774b0
https://doi.org/10.1111/j.1365-2958.2007.06038.x
https://doi.org/10.1111/j.1365-2958.2007.06038.x