Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Christos Vaklavas"'
Autor:
John Marsiglio, Jordan P. McPherson, Magdalena Kovacsovics-Bankowski, Joanne Jeter, Christos Vaklavas, Umang Swami, Douglas Grossmann, Alyssa Erickson-Wayman, Heloisa P. Soares, Katie Kerrigan, Berit Gibson, Jennifer Anne Doherty, John Hyngstrom, Sheetal Hardikar, Siwen Hu-Lieskovan
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundType 1 diabetes mellitus (T1DM) is a rare, but serious immune-related adverse event (irAE) of immune checkpoint inhibitors (ICIs). Our goal was to characterize treatment outcomes associated with ICI-induced T1DM through analysis of clinical
Externí odkaz:
https://doaj.org/article/33e51152bcc24a469b71e51e480b2741
Autor:
Jeffrey P. Leal, Steven P. Rowe, Vered Stearns, Roisin M. Connolly, Christos Vaklavas, Minetta C. Liu, Anna Maria Storniolo, Richard L. Wahl, Martin G. Pomper, Lilja B. Solnes
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Applications based on artificial intelligence (AI) and deep learning (DL) are rapidly being developed to assist in the detection and characterization of lesions on medical images. In this study, we developed and examined an image-processing workflow
Externí odkaz:
https://doaj.org/article/6602353622f148f4af0f80f202dac714
Autor:
Erica M. Stringer-Reasor, Jori E. May, Eva Olariu, Valerie Caterinicchia, Yufeng Li, Dongquan Chen, Deborah L. Della Manna, Gabrielle B. Rocque, Christos Vaklavas, Carla I. Falkson, Lisle M. Nabell, Edward P. Acosta, Andres Forero-Torres, Eddy S. Yang
Publikováno v:
Breast Cancer Research, Vol 23, Iss 1, Pp 1-12 (2021)
Abstract Background Poly (ADP-ribose)-polymerase inhibitors (PARPi) have been approved for cancer patients with germline BRCA1/2 (gBRCA1/2) mutations, and efforts to expand the utility of PARPi beyond BRCA1/2 are ongoing. In preclinical models of tri
Externí odkaz:
https://doaj.org/article/73538d58c45c449bae948e795b13f120
Autor:
Christos Vaklavas, Brian S. Roberts, Katherine E. Varley, Nancy U. Lin, Minetta C. Liu, Hope S. Rugo, Shannon Puhalla, Rita Nanda, Anna Maria Storniolo, Lisa A. Carey, Mansoor N. Saleh, Yufeng Li, Jennifer F. Delossantos, William E. Grizzle, Albert F. LoBuglio, Richard M. Myers, Andres Forero-Torres, on behalf of the Translational Breast Cancer Research Consortium (TBCRC)
Publikováno v:
Breast Cancer Research, Vol 22, Iss 1, Pp 1-15 (2020)
Abstract Background In preclinical studies, the expression of vascular endothelial growth factor (VEGF) in hormone receptor-positive breast cancer is associated with estrogen-independent tumor growth and resistance to endocrine therapies. This study
Externí odkaz:
https://doaj.org/article/5584ed790988432a9d02c709cacd449f
Publikováno v:
Translational Oncology, Vol 13, Iss 2, Pp 452-470 (2020)
Gene expression is extensively and dynamically modulated at the level of translation. How cancer cells prioritize the translation of certain mRNAs over others from a pool of competing mRNAs remains an open question. Here, we analyze translation in ce
Externí odkaz:
https://doaj.org/article/d14342c7e4ce4790ae8a0aa44cb52b78
Publikováno v:
APL Bioengineering, Vol 5, Iss 2, Pp 029901-029901-1 (2021)
Externí odkaz:
https://doaj.org/article/dfdb34176d4a4fdebc71b818ec438fba
Publikováno v:
APL Bioengineering, Vol 5, Iss 1, Pp 010901-010901-4 (2021)
Human cancer is a complex and heterogeneous collection of diseases that kills more than 18 million people every year worldwide. Despite advances in detection, diagnosis, and treatments for cancers, new strategies are needed to combat deadly cancer
Externí odkaz:
https://doaj.org/article/b02723fc989a45c395ca5f612404f280
Autor:
Adriana M Coletta, Mary C Playdon, Kelly G Baron, Mei Wei, Kristen Kelley, Christos Vaklavas, Anna Beck, Saundra S Buys, Jonathan Chipman, Cornelia M Ulrich, Darren Walker, Shelley White, Sonal Oza, Rebecca W Zingg, Pamela A Hansen
Publikováno v:
PLoS ONE, Vol 16, Iss 10, p e0258135 (2021)
ObjectiveTo assess the relationship between time-of-day of exercise training and changes in relevant cancer health outcomes among cancer survivors.MethodsRetrospective analysis of data collected from 2016-2019 from a hospital-based exercise oncology
Externí odkaz:
https://doaj.org/article/71d84dd94a374ca98613c0b9dc0b7ada
Publikováno v:
Frontiers in Oncology, Vol 7 (2017)
Although transcript levels have been traditionally used as a surrogate measure of gene expression, it is increasingly recognized that the latter is extensively and dynamically modulated at the level of translation (messenger RNA to protein). Over the
Externí odkaz:
https://doaj.org/article/c9e66e3ac23f4ab1b91fcc0c9ac348fe
Autor:
Katherine E. Varley, Albert F. LoBuglio, Richard M. Myers, Donald J. Buchsbaum, Christos Vaklavas, Todd C. Burwell, Erinn Downs-Kelly, Natalie D. Merz, Katherine L. Updike, William E. Grizzle, Dongquan Chen, Yufeng Li, Andres Forero
This file contains: Supplementary Methods for Tissue Processing, RNA-seq, RNA-seq analysis, and Immunohistochemistry. Supplementary Figure 1: Overlap between clusters identified in our data and TNBC subtypes described in previous studies. Supplementa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fc0ebc556aafb5e0bffd7f3a5ecaae1
https://doi.org/10.1158/2326-6066.22537210.v1
https://doi.org/10.1158/2326-6066.22537210.v1